Magnetic resonance imaging, evoked responses and cerebrospinal fluid findings in a follow-up study of children with optic neuritis

1988 ◽  
Vol 77 (1) ◽  
pp. 44-49 ◽  
Author(s):  
Dr.R. Riikonen ◽  
L. Ketonen ◽  
J. Sipponen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Optic Neuritis ◽  
Evoked Responses ◽  
Resonance Imaging ◽  
Follow Up Study

Multiple sclerosis-associated retrovirus and optic neuritis

2006 ◽  
Vol 12 (3) ◽  
pp. 357-359 ◽  
Author(s):  
S Sotgiu ◽  
G Arru ◽  
M Söderström ◽  
G Mameli ◽  
C Serra ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Prognostic Factor ◽  
Optic Neuritis ◽  
Resonance Imaging ◽  
Specific Study ◽  
Magnetic Resonance Imaging Mri

One prognostic factor for early multiple sclerosis (MS) patients to develop a definite MS may be the presence of the MS-associated retrovirus (MSRV) in the cerebrospinal fluid (CSF). We designed a specific study on a cohort of optic neuritis (ON) patients to evaluate the MSRV-dependent conversion to MS relative to the prediction conferred by magnetic resonance imaging (MRI) and CSF abnormalities. At follow-up, 33.3% MSRV+ and 0% MSRV− ON patients developed MS ( P=0.03). The prediction value is lower than that given by CSF and MRI abnormalities (42.3%). This intriguing finding is discussed in the light of the abundant discrepancies observed in the MSRV literature.

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