Identifying children at high somatic risk (?1antitrypsin deficiency): possible long-term effects on parents' reproduction, marital status and social class level

1985 ◽  
Vol 71 (6) ◽  
pp. 636-643 ◽  
Author(s):  
T. Thelin ◽  
T. F. McNeil ◽  
T. Sveger
Keyword(s):  
Social Class ◽  
Marital Status ◽  
Long Term Effects ◽  
Class Level

Housing Pathways and Stratification: Some Evidence from a British National Survey

1984 ◽  
Vol 13 (2) ◽  
pp. 147-165 ◽  
Author(s):  
O. Sullivan ◽  
M. J. Murphy
Keyword(s):  
Social Class ◽  
Large Scale ◽  
National Level ◽  
Small Scale ◽  
Long Term Effects ◽  
Nationally Representative ◽  
Changes Over Time ◽  
Housing Pathways ◽  
Socio Economic Factors

AbstractFive principles determining movement in the housing market relating to tenure, social class and fertility status were suggested by Payne and Payne (1977) on the basis of a small-scale study in Aberdeen. Analysis of a large-scale nationally-representative survey containing full housing and maternity histories suggests that some of these principles require modification at the national level. For example, movement into and between tenures, although heavily influenced by demographic and socio-economic factors, is not as rigid as the Aberdeen study suggested. The interaction of social class, age at marriage and childbearing patterns is assessed. Finally, changes over time in these relationships and the long-term effects on final family size and tenure are discussed.

MOTIVATION AND CLASS MOBILITY IN ENGLAND: LONGITUDINAL EVIDENCE OF A CAUSAL RELATIONSHIP

1990 ◽  
Vol 18 (1) ◽  
pp. 81-86
Author(s):  
Lawrence W. Littig
Keyword(s):  
Social Class ◽  
Causal Relationship ◽  
Test Anxiety ◽  
Occupational Attainment ◽  
Early Age ◽  
Occupational Class ◽  
Class Mobility ◽  
Class Level ◽  
Occupational Social Class

Relationships between motive to avoid failure and long-term occupational social class mobility were examined. Individuals low in motive to avoid failure, operationalized as test anxiety, were upwardly mobile in social class level of occupational attainment from 1966 to 1985; individuals high in motive to avoid failure were not. A cause-effect relationship was inferred; a strong avoidance motive inhibited upward occupational class mobility. The data suggest that individuals with high motive to avoid failure reach a ceiling occupational class level at a relatively early age whereas individuals with low motive to avoid failure continue longer to achieve further upward mobility. Implications of motive causality are discussed.

scholarly journals Long-term medical and social consequences of underage labor

2020 ◽  
Vol 14 (5) ◽  
pp. 630-633
Author(s):  
E. S. Mikhaylin
Keyword(s):  
Marital Status ◽  
Pregnancy Rate ◽  
Educational Program ◽  
Educational Programs ◽  
Social Consequences ◽  
Long Term Effects ◽  
Significant Difference

The long-term effects (marital status, attitude to breastfeeding, re-pregnancy rate) underage (aged 13-17 years) labor who gave birth within and outside the specialized educational program were studied. It was revealed that the girls who attended program classes, continued breastfeeding significantly longer. At the same time, no significant difference in the frequency of early re-pregnancy was found. Apparently, educational programs are not effective enough and require revision.

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

Long-Term Effects of Head Lice Tx Unknown

2012 ◽  
Vol 43 (3) ◽  
pp. 42
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  
Head Lice ◽  
Long Term Effects

The response of skin perfusion and of rheological and immunological variables to intravenous prostanoid administration in Raynaud’s phenomenon secondary to collagenosis

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Plasma Viscosity ◽  
Laser Doppler ◽  
Erythrocyte Aggregation ◽  
Control Group ◽  
Long Term Effects ◽  
Doppler Flowmetry

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.

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