First outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a Norwegian neonatal intensive care unit; associated with contaminated breast milk and resolved by strict cohorting

Apmis ◽  
2012 ◽  
Vol 120 (8) ◽  
pp. 612-621 ◽  
Author(s):  
Siren Rettedal ◽  
Iren H. Löhr ◽  
Olav Natås ◽  
Christian G. Giske ◽  
Arnfinn Sundsfjord ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Breast Milk ◽  
Klebsiella Pneumoniae ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Extended Spectrum

scholarly journals Characterization of an outbreak due to extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit

2021 ◽  
Author(s):  
Paola Pidal ◽  
Erna Cona ◽  
Carolina Torrejón ◽  
Contanza Airola ◽  
Javier Cifuentes ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Breast Milk ◽  
Klebsiella Pneumoniae ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Control Measures ◽  
Effective Control ◽  
Contact Precautions ◽  
Extended Spectrum

Background: The epidemiological–microbiological characteristics and effective intervention measures in an outbreak due to extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae in a neonatal intensive care unit are described. Materials and methods: Cases from June 22, 2018 to February 11, 2019 were analyzed. Microbiological analysis of intestinal carriage of ESBL-producing K. pneumoniae and environmental samples was conducted. Strain relationships were studied by pulsed-field gel electrophoresis (PFGE). Results: A 35-week outbreak affecting 41 patients, with eight infected, 33 colonized, and two deceased patients occurred. Two stages of the outbreak were observed with differences in the frequency of intestinal carriage of ESBL-producing K. pneumoniae. The same genetic subtype was seen in patient strains and was different from strains isolated from the environment. Deficiencies in contact precautions, hand hygiene, and handling of breast milk were observed. Conclusions: A monoclonal outbreak by ESBL-producing K. pneumoniae that occurred in two phases and the different control measures in each of the stages is described. Effective control measures are mainly based on improving compliance with standard precautions and contact precautions, and other complementary measures are described such as proper handling of breast milk, periodic carriage studies, and the generation of three patient cohorts.

An Outbreak of Extended-Spectrum β-Lactamase–Producing Klebsiella pneumoniae in a Neonatal Intensive Care Unit

2012 ◽  
Vol 33 (6) ◽  
pp. 631-634 ◽  
Author(s):  
Pranita D. Tamma ◽  
Patrice Savard ◽  
Tibor Pál ◽  
Ágnes Sonnevend ◽  
Trish M. Perl ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Source Of Infection ◽  
Extended Spectrum ◽  
Large Outbreak ◽  
Invasive Infections

We present a large outbreak of ESBL-producing Klebsiella pneumoniae in a neonatal intensive care unit that resulted in 31 colonized infants, 10 invasive infections, and 5 attributable deaths over a 5-month period. Although the source of infection was unknown, overcrowding and understaffing appeared to have been aggravating factors.

Prompt Control of an Outbreak Caused by Extended-Spectrum β-Lactamase–Producing Klebsiella pneumoniae in a Neonatal Intensive Care Unit

2013 ◽  
Vol 163 (3) ◽  
pp. 672-679.e3 ◽  
Author(s):  
Joseph B. Cantey ◽  
Pranavi Sreeramoju ◽  
Mambarambath Jaleel ◽  
Sylvia Treviño ◽  
Rita Gander ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Extended Spectrum

Extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a Neonatal Intensive Care Unit in León, Nicaragua

2009 ◽  
Vol 33 (4) ◽  
pp. 386-387 ◽  
Author(s):  
Erick Amaya ◽  
Mercedes Caceres ◽  
Hong Fang ◽  
Angel Torres Ramirez ◽  
Ann Cathrin Palmgren ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Extended Spectrum
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