Contact allergy to (meth)acrylates in the dental series in southern Sweden: simultaneous positive patch test reaction patterns and possible screening allergens

Objectives: Chronic spontaneous urticaria (CSU) is defined as short lived (< 24h) wheals occurring spontaneously without any triggering factors, daily or almost daily for at least 6 weeks. Though CSU is mainly a Type 1 hypersensitivity reaction, earlier studies suggested contact allergy may have some role to play an important role in the etiopathogenesis of CSU. The objective of the study is to find out the relevance of patch test in the etiopathogenesis of and its correlation with serum IgE level. Materials and Methods: Thirty-one patients of CSU were thoroughly evaluated for clinical and laboratory parameters. We conducted patch testing with Indian Standard Series (ISS) in all of them and tried to find out the relevance of every positive reaction. Relevant positive cases were asked to avoid exposure for 2 months and were maintained only in breakthrough antihistamines. Furthermore, correlation of positive patch test reaction with high IgE and eosinophil count were studied. Results: Seventeen (55%) cases came positive for patch test. Potassium dichromate, lanolin, benzocaine, and fragrance mix were the most common offenders. Patients with very high IgE count had patch test positivity with multiple allergens. Seven of the fifteen patients who had relevant positive patch results could be followed up to remission; three were lost to follow-up. Conclusion: Patch test with ISS may give important clue to in a subset of patients of CSU and thus may be considered an important part of routine investigations of CSU.

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Contact Sensitization to the Allergens of European Baseline Series in Patients With Chronic Leg Ulcers

Medicina ◽

10.3390/medicina47090072 ◽

2011 ◽

Vol 47 (9) ◽

pp. 480 ◽

Cited By ~ 12

Author(s):

Aistė Beliauskienė ◽

Skaidra Valiukevičienė ◽

Brigita Šitkauskienė ◽

Axel Schnuch ◽

Wolfgang Uter

Keyword(s):

Patch Test ◽

Contact Allergy ◽

Lower Leg ◽

Leg Ulcers ◽

Contact Sensitization ◽

Test Reaction ◽

Data Set ◽

Positive Patch Test ◽

Test Reactions ◽

Chronic Leg Ulcers

Background and Objective. The pattern of contact sensitization among patients with chronic leg ulcers depends on the local practice of wound treatment along with demographic and clinical confounders. The study was aimed at revealing the associations between chronic leg ulcers and contact sensitization. Material and Methods. Between 2006 and 2008, 35 patients with chronic leg ulcers and surrounding dermatitis and 59 patients with contact dermatitis of the lower leg or foot were prospectively recruited at the Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences. Demographic and clinical data were collected in accordance with the “minimal data set” of the European Surveillance System on Contact Allergy. Patch testing was performed with the allergens of the European baseline series. Results. At least one positive patch test reaction was found in 28 (80%) of the patients with chronic leg ulcers and in 24 (41%) of the patients with dermatitis of the lower leg or foot (P<0.001). Sensitization to some of the most common allergens, namely colophony, Myroxylon pereirae resin, and methyldibromo glutaronitrile, was prevalent in both the groups of patients, whereas sensitization to benzocaine, p-phenylenediamine, and lanolin alcohol was associated with the presence of chronic leg ulcers. Benzocaine was found to be the leading allergen among patients with chronic leg ulcers (positive patch test reactions in 34.4% of the patients). Conclusions. Contact sensitization to benzocaine, p-phenylenediamine, and lanolin was found to be associated with the presence of chronic leg ulcers.

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First case of skin allergy to pregabalin with positive patch test reaction

Contact Dermatitis ◽

10.1111/cod.13249 ◽

2019 ◽

Vol 81 (1) ◽

pp. 78-78 ◽

Cited By ~ 5

Author(s):

Elisa Gómez Torrijos ◽

Lucía Moreno Lozano ◽

Alba Mª Extrmera Ortega ◽

Oscar Gonzalez Jimenez ◽

Alejandro R. Gratacós Gómez ◽

...

Keyword(s):

Patch Test ◽

Test Reaction ◽

Positive Patch Test ◽

First Case ◽

Skin Allergy

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Positive patch test reaction against pityrosporum orbiculare in atopic dermatitis patients

Journal of Dermatological Science ◽

10.1016/s0923-1811(98)84016-4 ◽

1998 ◽

Vol 16 ◽

pp. S170

Author(s):

Maria Tengvall Linder ◽

Carl-Fredrik Wahlgren ◽

Catharina Johansson ◽

Annika Scheynius

Keyword(s):

Atopic Dermatitis ◽

Patch Test ◽

Test Reaction ◽

Positive Patch Test ◽

Pityrosporum Orbiculare

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Using Patch Testing to Improve Therapeutic Outcome in the Treatment of Hand Eczema in Vietnamese Patients

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.051 ◽

2019 ◽

Vol 7 (2) ◽

pp. 204-207 ◽

Cited By ~ 1

Author(s):

Phuong Pham Thi Minh ◽

Trang Thi Minh ◽

Doanh Le Huu ◽

Thuong Nguyen Van ◽

Sau Nguyen Huu ◽

...

Keyword(s):

Contact Dermatitis ◽

Patch Test ◽

Clinical Features ◽

Potassium Dichromate ◽

Nickel Sulfate ◽

Hand Eczema ◽

Test Reaction ◽

Positive Patch Test ◽

Causative Agents ◽

Allergic Contact

BACKGROUND: Hand eczema is a common chronic and relapsing skin disease with various clinical features. Hand eczema aetiology can be allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), atopic dermatitis (AD) and unknown or combination causes. If the causative agents are not detected treatment of hand eczema will be a failure. A patch test can be useful to detect causative agents in suspected allergic contact hand eczema. Then patients will avoid contacting them. This results in the improvement of hand eczema. In Vietnam, patch test has not been used before, so we conduct this study. AIM: To identify causative allergens by using patch test with 28 standard allergens in consecutive patients. METHODS: A group of 300 HE patients from the National Hospital of Dermatology and Venereology (NHDV) in Vietnam were enrolled in this study. They were divided into 4 groups-ACD, ICD, AD and unknown aetiology. The patient was patch tested with 28 standard allergens to identify the causative agents. RESULTS: Among the 300 HE enrolled patients, ACD accounted for 72.7%, AD and ICD had the same rate of 12.7%. 39.3% of the patients had a positive patch test. Reaction to nickel sulfate was the most common (10.3%), followed by potassium dichromate (9.7%), cobalt (4%) and fragrance mix (3.1%). About one-third of the cases had relevant clinical reactions correlated with the contact agents and clinical history. Males reacted to cement, thiuram mix and formaldehyde more than females, while females reacted to a nickel more than males. CONCLUSIONS: Hand eczema has variable clinical features and diverse aetiology. ACD is an important cause of hand eczema that can be managed with a patch test to detect causative allergens. Nearly 40% of HE cases had positive patch test. Relevant patch test reactions were seen in one-third of the patients. We propose using patch test detect causative agents in suspected allergic contact hand eczema. Then patients will avoid contacting them. This results in the improvement of hand eczema.

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Tiopronin-induced Lichenoid Eruption in a Patient with Liver Disease and Positive Patch Test Reaction to Drugs with Sulfhydryl Group

The Journal of Dermatology ◽

10.1111/j.1346-8138.1990.tb01621.x ◽

1990 ◽

Vol 17 (3) ◽

pp. 176-181 ◽

Cited By ~ 16

Author(s):

Yuko Kurumaji ◽

Kazuhiro Miyazaki

Keyword(s):

Liver Disease ◽

Patch Test ◽

Sulfhydryl Group ◽

Test Reaction ◽

Positive Patch Test ◽

Lichenoid Eruption

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Patch Testing in Lao medical students

10.1101/631903 ◽

2019 ◽

Author(s):

Catriona I. Wootton ◽

Mick Soukavong ◽

Sonexai Kidoikhammouan ◽

Bounthome Samountry ◽

John S.C. English ◽

...

Keyword(s):

Medical Students ◽

Patch Test ◽

Patch Testing ◽

Contact Allergy ◽

Background Level ◽

Future Research ◽

Formaldehyde Resin ◽

Test Results ◽

Positive Patch Test ◽

Cobalt Dichloride

AbstractBackgroundDermatological services in Laos, South East Asia are limited to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population.ObjectivesThe aim of this study was to document common allergens in medical students in Laos. Patients/Materials/MethodsOne hundred and fifty medical students were patch tested using TRUE Test® panels 1 to 3 (35 allergens). Readings were taken at Days 2 and 4.ResultsThirty-eight students (25.3%) had a positive reaction to at least one allergen, accounting for 52 reactions in total. The proportion of the students with positive patch test reading was significantly higher in the female [33/96 (34%)] than in the male [5/54 (9%)], p<0.001. The most common allergens were: nickel (10%), gold (6.6%), thiomersal (6.6%), cobalt dichloride (2%) and p-tert-Butylphenol formaldehyde resin (2%). Balsam of Peru (0.66%), black rubber mix (0.66%), Cl+Me-Isothiazolinone (0.66%), fragrance mix 1 (0.66%), quinolone mix (0.66%), methyldibromo glutaronitrile (0.66%), mercapto mix (0.66%), epoxy resin (0.66%), paraben mix (0.66%), thiuram (0.66%) and wool alcohols (0.66%) accounted for all of the other positive reactions.ConclusionThis study represents the first documented patch test results in Lao medical students and in the adult Lao population. The results of this study will inform any future research into contact allergy in Laos and give an insight into the background level of contact sensitivity in this population.

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