scholarly journals Patch Testing in Lao medical students

2019 ◽  
Author(s):  
Catriona I. Wootton ◽  
Mick Soukavong ◽  
Sonexai Kidoikhammouan ◽  
Bounthome Samountry ◽  
John S.C. English ◽  
...  
Keyword(s):  
Medical Students ◽  
Patch Test ◽  
Patch Testing ◽  
Contact Allergy ◽  
Background Level ◽  
Future Research ◽  
Formaldehyde Resin ◽  
Test Results ◽  
Positive Patch Test ◽  
Cobalt Dichloride

AbstractBackgroundDermatological services in Laos, South East Asia are limited to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population.ObjectivesThe aim of this study was to document common allergens in medical students in Laos. Patients/Materials/MethodsOne hundred and fifty medical students were patch tested using TRUE Test® panels 1 to 3 (35 allergens). Readings were taken at Days 2 and 4.ResultsThirty-eight students (25.3%) had a positive reaction to at least one allergen, accounting for 52 reactions in total. The proportion of the students with positive patch test reading was significantly higher in the female [33/96 (34%)] than in the male [5/54 (9%)], p<0.001. The most common allergens were: nickel (10%), gold (6.6%), thiomersal (6.6%), cobalt dichloride (2%) and p-tert-Butylphenol formaldehyde resin (2%). Balsam of Peru (0.66%), black rubber mix (0.66%), Cl+Me-Isothiazolinone (0.66%), fragrance mix 1 (0.66%), quinolone mix (0.66%), methyldibromo glutaronitrile (0.66%), mercapto mix (0.66%), epoxy resin (0.66%), paraben mix (0.66%), thiuram (0.66%) and wool alcohols (0.66%) accounted for all of the other positive reactions.ConclusionThis study represents the first documented patch test results in Lao medical students and in the adult Lao population. The results of this study will inform any future research into contact allergy in Laos and give an insight into the background level of contact sensitivity in this population.

scholarly journals Relevance of patch testing in patients of chronic spontaneous urticaria and its correlation with serum IgE level

2022 ◽  
Vol 1 ◽  
pp. 17-20
Author(s):  
Trupti Desale ◽  
Abhishek De ◽  
S. K. Shahriar Ahmed ◽  
Aarti Sarda ◽  
Kiran Godse ◽  
...  
Keyword(s):  
Patch Test ◽  
Patch Testing ◽  
Potassium Dichromate ◽  
Contact Allergy ◽  
Chronic Spontaneous Urticaria ◽  
Test Reaction ◽  
Serum Ige ◽  
Positive Patch Test ◽  
Lost To Follow Up

Objectives: Chronic spontaneous urticaria (CSU) is defined as short lived (< 24h) wheals occurring spontaneously without any triggering factors, daily or almost daily for at least 6 weeks. Though CSU is mainly a Type 1 hypersensitivity reaction, earlier studies suggested contact allergy may have some role to play an important role in the etiopathogenesis of CSU. The objective of the study is to find out the relevance of patch test in the etiopathogenesis of and its correlation with serum IgE level. Materials and Methods: Thirty-one patients of CSU were thoroughly evaluated for clinical and laboratory parameters. We conducted patch testing with Indian Standard Series (ISS) in all of them and tried to find out the relevance of every positive reaction. Relevant positive cases were asked to avoid exposure for 2 months and were maintained only in breakthrough antihistamines. Furthermore, correlation of positive patch test reaction with high IgE and eosinophil count were studied. Results: Seventeen (55%) cases came positive for patch test. Potassium dichromate, lanolin, benzocaine, and fragrance mix were the most common offenders. Patients with very high IgE count had patch test positivity with multiple allergens. Seven of the fifteen patients who had relevant positive patch results could be followed up to remission; three were lost to follow-up. Conclusion: Patch test with ISS may give important clue to in a subset of patients of CSU and thus may be considered an important part of routine investigations of CSU.

scholarly journals Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Hai-yan Cheng ◽  
Lin-feng Li
Keyword(s):  
Contact Dermatitis ◽  
Patch Test ◽  
Contact Allergy ◽  
Nickel Sulfate ◽  
Tibetan Medicine ◽  
Control Group ◽  
Irritant Contact Dermatitis ◽  
Test Results ◽  
Biophysical Parameters ◽  
Nickel Allergy

Background. Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact dermatitis (ICD) caused by XTT is very common. It is still unclear why some people are more prone to develop ICD. The aim of this study is to study the baseline skin biophysical parameters and patch test results in individuals predisposing to XTT induced ICD. Methods. During a four-month period, 149 healthy volunteers with ICD and 50 volunteers without ICD after applying XTT were recruited. The skin biophysical parameters were measured, and contact allergy to 20 common allergens was patch tested, at two weeks after the ICD was recovered. Results. There were no significant differences in age and sex between ICD and control groups. It was found that skin median melanin value (176.50 vs 189.50, P < 0.05, Mann-Whitney U-test) and erythema value (319.90 ± 70.49 vs 347.93 ± 84.55, P < 0.05, Independent-Samples T test) were much lower in ICD than control group. Overall patch test results were not different, but the positivity rate of nickel sulfate (15.44% vs 4.00%, P < 0.05, Fisher’s exact test) was significantly higher in ICD group. Conclusions. In conclusion, people with nickel allergy, lower values of skin melanin, and erythema are predisposing to develop ICD.

scholarly journals Impact of Patch Testing on Quality of Life in Patients with Hand Eczema: A Follow-up Study

2015 ◽  
Vol 11 (3) ◽  
pp. 216-220 ◽  
Author(s):  
S Agrawal ◽  
A Rijal ◽  
S Bhattarai
Keyword(s):  
Quality Of Life ◽  
Patch Test ◽  
Patch Testing ◽  
Life Quality ◽  
Hand Eczema ◽  
Patch Tests ◽  
Positive Patch Test ◽  
Sum Score ◽  
The Impact

Background Patch testing has previously been shown to influence the quality of life, although a very few studies have shown if this is dependent on the result of the patch tests. Objective To assess the impact of patch testing on the quality of life (QOL) in patients with hand eczema (HE). Methods A total of 50 patients diagnosed of hand eczema at the time of patch testing, aged 16 years and above participated in this study. Detailed demographic information and diagnosis of hand eczema were collected on the day of the patch test. After six weeks, the patients were asked about the hand eczema, knowledge of their allergies and change in their life style to avoid the relevant allergens demonstrated on the patch test. Dermatology Life Quality Index (DLQI) was used to measure the QOL on both occasions. Results The patch test positivity was found in 68% of patients to one or more allergens. The sum score of DLQI at baseline was 12.16 ± 5.58 with median 12.0. HE had most impact on symptoms and feelings. Patients with both positive patch test (mean baseline= 11.94± 5.88; mean at six weeks=2.81± 2.01; P<0.001) and negative patch test (mean baseline=12.63± 5.03; mean at 6 weeks=5.4± 3.56; P=0.001) showed significant improvement in DLQI scores, however it was more improved in patients with positive patch test than in patients with negative patch test. Conclusions Hand eczema had an appreciable impact on the QOL. Patch testing had been beneficial to most patients in improving patient quality of life considerably. DOI: http://dx.doi.org/10.3126/kumj.v11i3.12506 Kathmandu Univ Med J 2013; 43(3):216-220

Red scrotum syndrome: idiopathic neurovascular phenomenon or steroid addiction?

Sexual Health ◽  
2013 ◽  
Vol 10 (5) ◽  
pp. 452 ◽  
Author(s):  
Tarun Narang ◽  
Muthu Sendhil Kumaran ◽  
Sunil Dogra ◽  
Uma Nahar Saikia ◽  
Bhushan Kumar
Keyword(s):  
Skin Biopsy ◽  
Patch Test ◽  
Patch Testing ◽  
Average Duration ◽  
Topical Steroid ◽  
Burning Sensation ◽  
Treatment Modalities ◽  
Test Results ◽  
Steroid Use ◽  
Duration Of Illness

Background Red scrotum syndrome (RSS) is not infrequent but is often misdiagnosed or underdiagnosed, and seldom reported. The exact etiopathogeneis is still unknown but it almost always follows the prolonged application of topical corticosteroids and is characterised by persistent erythema of the scrotum, associated with severe itching, hyperalgesia and a burning sensation. Objective: To evaluate the clinicoepidemiological profile and assess the efficacy of various treatment modalities in addition to corticosteroid abstinence in the treatment of RSS. Methods: Twelve patients with RSS, who presented to us during 2010 and 2011, were identified, and various aspects of their illness and treatment were studied. Patch testing was performed in all patients. A skin biopsy was done in seven patients. Results: The average age of the patients was 45.83 years (26–62 years). The average duration of illness or the duration of topical steroid use was 27.41 months (6–56 months). Psychiatric comorbidities were seen in 9 (75%) out of 12 patients. Histopathology revealed features resembling erythematotelengiectatic rosacea in four of the biopsied patients. Patch test results were negative. All patients reported improvement of their symptoms within 4 weeks of starting doxycycline with amitriptyline or pregabalin; the treatment had to be continued for 3–4 months. Conclusions: RSS appears to be a manifestation of corticosteroid misuse rather than a primary disease. We suggest that RSS is a rosacea-like dermatosis or steroid-induced rebound vasodilation based on clinical and histopathological features. Our patients responded to cessation of steroids and doxycycline in combination with amitryptaline or pregabalin.

Increase in contact allergy to fragrances: patch-test results 1989-1998

2000 ◽  
Vol 43 (2) ◽  
pp. 107-109 ◽  
Author(s):  
Tomaž Lunder ◽  
Aleksej Kansky
Keyword(s):  
Patch Test ◽  
Contact Allergy ◽  
Test Results

scholarly journals Contact Sensitization to the Allergens of European Baseline Series in Patients With Chronic Leg Ulcers

Medicina ◽  
2011 ◽  
Vol 47 (9) ◽  
pp. 480 ◽  
Author(s):  
Aistė Beliauskienė ◽  
Skaidra Valiukevičienė ◽  
Brigita Šitkauskienė ◽  
Axel Schnuch ◽  
Wolfgang Uter
Keyword(s):  
Patch Test ◽  
Contact Allergy ◽  
Lower Leg ◽  
Leg Ulcers ◽  
Contact Sensitization ◽  
Test Reaction ◽  
Data Set ◽  
Positive Patch Test ◽  
Test Reactions ◽  
Chronic Leg Ulcers

Background and Objective. The pattern of contact sensitization among patients with chronic leg ulcers depends on the local practice of wound treatment along with demographic and clinical confounders. The study was aimed at revealing the associations between chronic leg ulcers and contact sensitization. Material and Methods. Between 2006 and 2008, 35 patients with chronic leg ulcers and surrounding dermatitis and 59 patients with contact dermatitis of the lower leg or foot were prospectively recruited at the Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences. Demographic and clinical data were collected in accordance with the “minimal data set” of the European Surveillance System on Contact Allergy. Patch testing was performed with the allergens of the European baseline series. Results. At least one positive patch test reaction was found in 28 (80%) of the patients with chronic leg ulcers and in 24 (41%) of the patients with dermatitis of the lower leg or foot (P<0.001). Sensitization to some of the most common allergens, namely colophony, Myroxylon pereirae resin, and methyldibromo glutaronitrile, was prevalent in both the groups of patients, whereas sensitization to benzocaine, p-phenylenediamine, and lanolin alcohol was associated with the presence of chronic leg ulcers. Benzocaine was found to be the leading allergen among patients with chronic leg ulcers (positive patch test reactions in 34.4% of the patients). Conclusions. Contact sensitization to benzocaine, p-phenylenediamine, and lanolin was found to be associated with the presence of chronic leg ulcers.

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