No Association of C677T Methylenetetrahydrofolate Reductase and an Endothelial Nitric Oxide Synthase Polymorphism with Recurrent Pregnancy Loss

2004 ◽  
Vol 52 (1) ◽  
pp. 60-66 ◽  
Author(s):  
Aiko Makino ◽  
Tamao Nakanishi ◽  
Mayumi Sugiura-Ogasawara ◽  
Yasuhiko Ozaki ◽  
Nobuhiro Suzumori ◽  
...  
2005 ◽  
Vol 274 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Venkata Suryanarayana ◽  
Lakshmi Rao ◽  
Murthy Kanakavalli ◽  
Venkata Padmalatha ◽  
Mamata Deenadayal ◽  
...  

Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).


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