Manifestation of acute monocytic leukemia in the oral cavity: a case report

ABSTRACTAcute Myeloblastic Leukemia (AML) is a malignant disease of bone marrow. Due to its high morbidity rate, early diagnosis and appropriate medical therapy is essential. Rapidly forming gingival hyperplasia is usually the first sign of this disease. This case report describes a 17-year-old female who presented rapid gingival overgrowth together with gingival bleeding in only two weeks time. A medical consultation was asked from hematology clinics and after a detailed medical examination Acute Monocytic Leukemia (FAB M5) was rendered. Chemotherapy was the choice of treatment. The patient responded well to chemotherapeutic induction regimen and after two months of medical therapy disease remised and gingival hyperplasia regressed. This case report shows that the gingival hyperplasia may represent an initial manifestation of an underlying systemic disease. Also, early medical therapy in acute monocytic leukemia may resolve the gingival hyperplasia that companies the disease progression. (Eur J Dent 2007;2:111-114)

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Apparent Isolated Skin Relapse in Acute Monocytic Leukemia. A Case Report

Tumori Journal ◽

10.1177/030089169107700218 ◽

1991 ◽

Vol 77 (2) ◽

pp. 172-174 ◽

Cited By ~ 2

Author(s):

Livio Pagano ◽

Luigi Maria Larocca ◽

Marcella Zollino ◽

Simona Sica ◽

Sergio Storti ◽

...

Keyword(s):

Case Report ◽

Acute Monocytic Leukemia ◽

Monocytic Leukemia

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Fatal spleen rupture during induction chemotherapy with RH GM-CSF priming for acute monocytic leukemia. Clinical case report and in vitro studies

Leukemia Research ◽

10.1016/0145-2126(93)90012-a ◽

1993 ◽

Vol 17 (3) ◽

pp. 277-283 ◽

Cited By ~ 24

Author(s):

B.M. Zimmer ◽

W.E. Berdel ◽

W.-D. Ludwig ◽

M. Notter ◽

B. Reufi ◽

...

Keyword(s):

Case Report ◽

Induction Chemotherapy ◽

Clinical Case ◽

In Vitro Studies ◽

Acute Monocytic Leukemia ◽

Monocytic Leukemia ◽

Gm Csf ◽

Spleen Rupture

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Invasive Mycotic Infections in the Immunocompromised Child

Otolaryngology ◽

10.1177/019459987908700110 ◽

1979 ◽

Vol 87 (1) ◽

pp. 32-34 ◽

Cited By ~ 5

Author(s):

Mark I. Singer ◽

Jerome L. House

Keyword(s):

Case Report ◽

Infectious Diseases ◽

Acute Monocytic Leukemia ◽

Natural Immunity ◽

Monocytic Leukemia ◽

Vulnerable Group ◽

Immunocompromised Child ◽

Mycotic Infections ◽

Oncologic Therapy

Oncologic therapy creates a highly vulnerable group of children with little or no natural immunity. In addition to the problems of coagulopathies, these children are prone to unusual infectious diseases. One group of saprophytic infections, the mycotic organisms, represents stubborn and often lethal diseases challenging present diagnostic and therapeutic skils. This is a case report of invasive Aspergillus organisms in the nose and premaxilla in a 9-year-old child suffering from acute monocytic leukemia.

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Secondary Acute Monocytic Leukemia with a Translocation t(8;16)(p11;p13): Case Report and Review of the Literature

Leukemia & Lymphoma ◽

10.1080/10428190310001593058 ◽

2004 ◽

Vol 45 (3) ◽

pp. 621-625 ◽

Cited By ~ 15

Author(s):

Taizo Tasaka ◽

Yoshiko Matsuhashi ◽

Eisuke Uehara ◽

Takahiro Tamura ◽

Naoki Kakazu ◽

...

Keyword(s):

Case Report ◽

Acute Monocytic Leukemia ◽

Review Of The Literature ◽

Monocytic Leukemia

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Brief Case Report: Syndrome of Erythremia di Guglielmo after Lightning Injury with Autoimmune Antibodies and Terminating in Acute Monocytic Leukemia

Blood ◽

10.1182/blood.v25.5.845.845 ◽

1965 ◽

Vol 25 (5) ◽

pp. 845-849 ◽

Cited By ~ 8

Author(s):

LIE-INJO LUAN ENG ◽

C. SINNADURAI

Keyword(s):

Bone Marrow ◽

Folic Acid ◽

Case Report ◽

Peripheral Blood ◽

Acute Monocytic Leukemia ◽

Monocytic Leukemia ◽

Autoimmune Antibodies ◽

Lightning Injury ◽

High Doses ◽

Hemopoietic System

Abstract A case of lightning injury is described associated with changes of the hemopoietic system resembling di Guglielmo’s syndrome. Megaloblasts were found in the peripheral blood and bone marrow, resistant to folic acid and vitamin B12 treatment. The presence of auto-immune antibodies in this patient was accompanied by a hemolytic condition not responding to treatment with high doses of prednisolone. Towards the end of the disease the most bizarre-looking erythroblasts were seen in the peripheral blood. Shortly before death the condition suddenly changed into an acute monocytic leukemia. Although it was not proved that the lightning injury caused or precipitated the blood changes, it is thought not to be improbable.

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