Association of preservative‐free versus glaucoma eye drops with preservatives and further glaucoma surgery. A retrospective study based on the French national health insurance information system, 2008‐2016

Objective: Epidemiological surveillance of malaria in France is based on a hospital laboratory sentinel surveillance network. There is no comprehensive population surveillance. The objective of this study was to assess the ability of the French National Health Insurance Information System to support nationwide malaria surveillance in continental France. Materials and methods: A case identification algorithm was built in a 2-step process. First, inclusion rules giving priority to sensitivity were defined. Then, based on data description, exclusion rules to increase specificity were applied. To validate our results, we compared them to data from the French National Reference Center for Malaria on case counts, distribution within subgroups, and disease onset date trends. Results: We built a reusable automatized tool. From July 1, 2013, to June 30, 2014, we identified 4077 incident malaria cases that occurred in continental France. Our algorithm provided data for hospitalized patients, patients treated by private physicians, and outpatients for the entire population. Our results were similar to those of the National Reference Center for Malaria for each of the outcome criteria. Discussion: We provided a reliable algorithm for implementing epidemiological surveillance of malaria based on the French National Health Insurance Information System. Our method allowed us to work on the entire population living in continental France, including subpopulations poorly covered by existing surveillance methods. Conclusion: Traditional epidemiological surveillance and the approach presented in this paper are complementary, but a formal validation framework for case identification algorithms is necessary.

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10-year trends in statin utilization in Taiwan: a retrospective study using Taiwan’s National Health Insurance Research Database

BMJ Open ◽

10.1136/bmjopen-2016-014150 ◽

2017 ◽

Vol 7 (5) ◽

pp. e014150 ◽

Cited By ~ 19

Author(s):

Hsing-Chun Hsieh ◽

Jason C Hsu ◽

Christine Y Lu

Keyword(s):

Health Insurance ◽

Retrospective Study ◽

National Health Insurance ◽

National Health ◽

Research Database

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Medication Adherence and Persistence of Open-Angle Glaucoma Patients in Korea: A Retrospective Study Using National Health Insurance Claims Data

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18084106 ◽

2021 ◽

Vol 18 (8) ◽

pp. 4106

Author(s):

Yunjeong Jang ◽

Donghyun Jee ◽

Donghwan Lee ◽

Nam-Kyong Choi ◽

SeungJin Bae

Keyword(s):

Health Insurance ◽

Retrospective Study ◽

Medication Adherence ◽

National Health Insurance ◽

National Health ◽

Open Angle Glaucoma ◽

Medication Possession Ratio ◽

Open Angle ◽

Duration Of Therapy ◽

The Mean

This study aimed to analyze medication adherence and persistence among open-angle glaucoma patients in Korea. A retrospective study was conducted using the Korean National Health Insurance (NHI) claims database from 2016 to 2019. Newly diagnosed open-angle glaucoma patients who were prescribed with the intraocular pressure (IOP)-lowering eyedrops were included. Adherence was measured using the medication possession ratio (MPR), and persistence was measured using the duration of therapy during the 24 month follow-up period. During the study period, 14,648 open-angle glaucoma patients were identified, and 3118 (21.3%) and 4481 patients (30.6%) were adherent to and persistent with their glaucoma treatment, respectively. The mean MPR was 48.8%, and the mean duration of therapy was 357.2 days. Logistic regression analysis showed that patients who are older, female, using prostaglandins as the index medication, and visiting secondary or tertiary hospitals were significantly associated with greater rates of adherence (odds ratio (OR) = 1.21, 1.12, 1.27, and 1.73, respectively) and persistence (OR = 1.11, 1.17, 1.16, 1.17, and 1.36, respectively) during the study period. Patients with open-angle glaucoma in Korea had substandard medication adherence and discontinued their treatment. Ophthalmologists should pay more attention to younger, male patients to improve adherence.

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