A note on the effects of some cholinergic and anticholinergic drugs on the aggressive behaviour and spontaneous electrical activity of the central nervous system in the ant, Formica rufa

1968 ◽  
Vol 20 (5) ◽  
pp. 381-384 ◽  
Author(s):  
WOJCIECH KOSTOWSKI
1956 ◽  
Vol 185 (3) ◽  
pp. 601-606 ◽  
Author(s):  
Alan G. Slocombe ◽  
Hudson Hoagland ◽  
Lillian S. Tozian

Lysergic acid diethylamide (LSD), 5-hydroxytryptamine, and adrenochrome were shown to have properties similar to epinephrine in their effects on the spontaneous electrical activity in the brain of the albino rat. The effects of these drugs were shown to be determined by the type of anesthetic used. In Pentothal-anesthetized animals, profound reduction of the electrical activity in both frequency and amplitude was found in response to these drugs, while in ether-anesthetized animals there was no significant effect. There was a tendency for LSD to increase electrical activity when injected following recovery from anesthesia. The significance of this differential response is discussed with respect to structures in the central nervous system primarily affected by ether and Pentothal, and it is suggested that the site of action of these compounds is in Pentothal-sensitive nonspecific pathways. The site of the depressive action of these drugs with Pentothal is further defined by the fact that both cortical and subcortical structures were equally affected, while respiratory and cardio-regulatory centers were not significantly depressed. This implicates one of the lower nonspecific centers with widespread cortical and subcortical projections.


1995 ◽  
Vol 56-63 ◽  
pp. 11-11
Author(s):  
B. Zale ◽  
C. Demerens ◽  
B. Stankoff ◽  
B. Allinquant ◽  
F Couraud§ ◽  
...  

2012 ◽  
Vol 12 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Dan-Thanh T. Nguyen ◽  
Melissa J. Blacker ◽  
James A. Goodchild

2018 ◽  
Vol 8 (1) ◽  
pp. 26-30
Author(s):  
Aliyev A. H. ◽  
Miryusifova Сh. M. ◽  
Aliyeva F. A. ◽  
Ibrahimova S. Sh.

The paper considers effects of the sodium salt of penicillin, on the bioelectric activity of the visual analyzer structures in rabbits. Penicillin was injected into the amygdale, and a focus was created in this structure. Modeling the epileptic focus in amygdale allows to detect the spread of excitation as in motor structures of the brain (clonic convulsions), and in various structures of the visual analyzer. A comparative analysis of the electrical activity of spe-cific (visual cortex, superior colliculus) and non-specific structures (suprachiasmatic nucleus of the hypothalamus) of the visual analyzer was performed in norm and after epileptic attacks. For this purpose, a coherent analysis of the electrical activity of the above-mentioned structures was per-formed in normal and after epileptic seizures. The experiments were carried out on rabbits. Registration and analysis of the electroencephalogram of various brain structures was performed by using the automated system "Brainsys". It is also established that there is a change in the coherent bonds between the structures of the visual analyzer after epileptic seizures. The coherence coefficient, except for the alpha range, increased in all structures compared with the background. The change in coherent bonds after epileptic seizures is explained by the activation of functional interactions between the structures of the central nervous system. The presence of high-amplitude theta and delta waves in the electroencephalogram indicates functional changes in the central nervous system. It is known that the visual analyzer has complex differentiated properties of plasticity. After epilepsy with the help of endogenous compensatory mechanisms it forms a new rela-tionship between the structures of the central nervous system.


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