scholarly journals The Relationship Between Nocturnal Blood Pressure and Hemorrhagic Stroke in Chinese Hypertensive Patients

2014 ◽  
Vol 16 (9) ◽  
pp. 652-657 ◽  
Author(s):  
Jialan Sun ◽  
Wanlin Yang ◽  
Yang Zhu ◽  
Xiaohong Liu ◽  
Xin Wei ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Hemorrhagic Stroke ◽  
Hypertensive Patients ◽  
Nocturnal Blood Pressure ◽  
The Relationship

scholarly journals Improvement of intestinal flora: accompany with the antihypertensive effect of electroacupuncture on stage 1 hypertension

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jun-meng Wang ◽  
Ming-xiao Yang ◽  
Qiao-feng Wu ◽  
Ji Chen ◽  
Shu-fang Deng ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Intestinal Microbiota ◽  
Antihypertensive Effect ◽  
Intestinal Flora ◽  
Hypertensive Patients ◽  
Healthy Group ◽  
Oscillometric Device ◽  
Intestinal Dysbiosis ◽  
Stage 1 ◽  
The Relationship

Abstract Background Increasing evidence have indicated the relationship between intestinal dysbiosis and hypertension. We aimed to evaluate the effect of the electroacupuncture (EA) on intestinal microbiota in patients with stage 1 hypertension. Methods 93 hypertensive patients and 15 healthy subjects were enrolled in this study. Applying a highly accurate oscillometric device to evaluate the antihypertensive effect of EA. 16S rRNA sequencing was used to profile stool microbial communities from Healthy group, Before treatment (BT) group and After treatment (AT) group, and various multivariate analysis approaches were used to assess diversity, composition and abundance of intestinal microbiota. Results In this study, EA significantly decreased the blood pressure (BP) of hypertensive patients. Higher abundance of Firmicutes and lower Bacteroidetes abundance were observed in the BT group compared to the Healthy group. And EA treatment significantly decreased the Firmicutes/Bacteroidetes ratio compared to the BT group. Moreover, at the genus level, there was an increased abundance of Escherichia-Shigella in patients with hypertension, while Blautia were decreased, and EA reversed these changes. Conclusions Our study indicates that EA can effectively lower BP and improve the structure of intestinal microbiota which are correlate with the alteration of blood pressure by electroacupuncture. Trial registration: Clinicaltrial.gov, NCT01701726. Registered 5 October 2012, https://clinicaltrials.gov/ct2/show/study/NCT01701726

scholarly journals Relationship between Plasma Trimethylamine N-Oxide Levels and Renal Dysfunction in Patients with Hypertension

2021 ◽  
pp. 1-12
Author(s):  
Jia Zhou ◽  
Dingkun Wang ◽  
Bingong Li ◽  
Xuelian Li ◽  
Xingjun Lai ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Kidney Disease ◽  
Renal Dysfunction ◽  
High Performance ◽  
Characteristic Curve ◽  
Area Under The Curve ◽  
Hypertensive Patients ◽  
Ckd Stage ◽  
Liquid Chromatography Tandem Mass ◽  
The Relationship

<b><i>Introduction:</i></b> Trimethylamine N-oxide (TMAO) is a metabolite produced by gut bacteria. Although increased TMAO levels have been linked to hypertension (HTN) and chronic kidney disease (CKD) with poor prognosis, no clinical studies have directly addressed the relationship between them. In this study, we investigated the relationship between TMAO and renal dysfunction in hypertensive patients. <b><i>Methods:</i></b> We included healthy controls (<i>n</i> = 50), hypertensive patients (<i>n</i> = 46), and hypertensive patients with renal dysfunction (<i>n</i> = 143). Their blood pressure values were taken as the highest measured blood pressure. Renal function was evaluated using the estimated glomerular filtration rate. Plasma TMAO levels were measured using high-performance liquid chromatography tandem mass spectrometry. <b><i>Results:</i></b> We found significant differences in plasma TMAO levels among the 3 groups (<i>p</i> &#x3c; 0.01). The plasma TMAO of patients with HTN was significantly higher than that of healthy people, and the plasma TMAO of patients with HTN complicated by renal dysfunction was significantly higher than either of the other groups. Patients in the highest TMAO quartile were at a higher risk of developing CKD stage 5 than those in the lowest quartile. In the receiver operating characteristic curve, the area under the curve of TMAO combined with β 2-macroglobulin for predicting renal dysfunction in patients with HTN was 0.85 (95% confidence interval 0.80–0.90). <b><i>Conclusion:</i></b> An elevated TMAO level reflects higher levels of HTN and more severe renal dysfunction. TMAO, combined with β 2-macroglobulin levels, may assist in diagnosing CKD in hypertensive patients. Plasma TMAO has predictive value for early kidney disease in hypertensive patients.

Prazosin-Induced First-Dose Phenomenon Possibly Associated with Hemorrhagic Stroke: A Report of Three Cases

1987 ◽  
Vol 21 (9) ◽  
pp. 723-726 ◽  
Author(s):  
Min-Shung Lin ◽  
Wen-Ju Hsieh
Keyword(s):  
Blood Pressure ◽  
Potential Risk ◽  
Initial Dose ◽  
Cerebral Hemorrhage ◽  
Hemorrhagic Stroke ◽  
Hypertensive Patients ◽  
Consciousness Disturbance

A small initial dose of prazosin ranging from 0.5 to 1 mg has been recommended to avoid the first-dose phenomenon characterized by a sudden and severe drop in blood pressure after the administration of the first dose of prazosin. However, even with an initial dose of 0.5 mg, hypotension with consciousness disturbance developed in three hypertensive patients with recent cerebral hemorrhage. We present this report to alert physicians and pharmacists about the potential risk of the first-dose phenomenon even at the recommended initial doses of prazosin in hypertensive patients who have suffered a recent stroke.

scholarly journals The relationship between dietary salt intake and ambulatory blood pressure variability in non-diabetic hypertensive patients

Nefrología ◽  
2016 ◽  
Vol 36 (6) ◽  
pp. 694-700 ◽  
Author(s):  
Nihal Ozkayar ◽  
Fatih Dede ◽  
Ihsan Ates ◽  
Fatma Akyel ◽  
Tolga Yildirim ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Variability ◽  
Salt Intake ◽  
Dietary Salt ◽  
Hypertensive Patients ◽  
Dietary Salt Intake ◽  
The Relationship

Not nondipping but nocturnal blood pressure predicts left ventricular hypertrophy in the essential hypertensive patients

2014 ◽  
Vol 32 (10) ◽  
pp. 1999-2004 ◽  
Author(s):  
Jeong-Eun Yi ◽  
Jinho Shin ◽  
Sang-Hyun Ihm ◽  
Ju Han Kim ◽  
Sungha Park ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Nocturnal Blood Pressure

scholarly journals Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Jenni M. Rimpelä ◽  
Ilkka H. Pörsti ◽  
Antti Jula ◽  
Terho Lehtimäki ◽  
Teemu J. Niiranen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Hypertensive Patients ◽  
Nocturnal Blood Pressure ◽  
Genome Wide ◽  
Blood Pressure Dipping ◽  
Nocturnal Blood Pressure Dipping
Sign in / Sign up

Export Citation Format

Share Document