scholarly journals Diabetic polyneuropathy: Progress in diagnostic strategy and novel target discovery, but stagnation in drug development

2019 ◽  
Vol 11 (1) ◽  
pp. 25-27
Author(s):  
Tatsuhito Himeno ◽  
Hideki Kamiya ◽  
Jiro Nakamura
Keyword(s):  
Drug Development ◽  
Diabetic Polyneuropathy ◽  
Diagnostic Strategy ◽  
Target Discovery ◽  
Novel Target

scholarly journals BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders

Neuron ◽  
2015 ◽  
Vol 88 (6) ◽  
pp. 1078-1083 ◽  
Author(s):  
Christian R. Schubert ◽  
Patricio O’Donnell ◽  
Jie Quan ◽  
Jens R. Wendland ◽  
Hualin S. Xi ◽  
...  
Keyword(s):  
Neuropsychiatric Disorders ◽  
Target Discovery ◽  
Novel Target

Drug development in IBD: from novel target identification to early clinical trials

Gut ◽  
2016 ◽  
Vol 65 (8) ◽  
pp. 1233-1239 ◽  
Author(s):  
Silvio Danese ◽  
Claudio Fiocchi ◽  
Julián Panés
Keyword(s):  
Clinical Trials ◽  
Drug Development ◽  
Target Identification ◽  
Novel Target

Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery

2010 ◽  
Vol 7 (2) ◽  
pp. 76-85 ◽  
Author(s):  
Hui Bai ◽  
Xiaoyan Xue ◽  
Zheng Hou ◽  
Ying Zhou ◽  
Jingru Meng ◽  
...  
Keyword(s):  
Target Discovery ◽  
Novel Target

Human pregnane X receptor: a novel target for anticancer drug development

2014 ◽  
Vol 19 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Vijay Rathod ◽  
Sumit Jain ◽  
Prajwal Nandekar ◽  
Abhay T. Sangamwar
Keyword(s):  
Drug Development ◽  
Anticancer Drug ◽  
Pregnane X Receptor ◽  
Novel Target ◽  
Anticancer Drug Development

scholarly journals Fast tracking drug development: balancing risks and rewards

2002 ◽  
Vol 23 (5) ◽  
pp. 20
Author(s):  
Harry Majewski
Keyword(s):  
Drug Design ◽  
Drug Development ◽  
High Throughput ◽  
Combinatorial Chemistry ◽  
High Throughput Screening ◽  
Target Discovery ◽  
New Therapies ◽  
Fast Tracking ◽  
Great Hope

The biotechnology revolution offers great hope for new therapies based on rational approaches to target discovery and drug design based on genomics, proteomics, advanced chemistry (3-D modelling, combinatorial chemistry) and high throughput screening.

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