In vitro anti-inflammatory and skin protective properties of extract comprising ceramides from de-oiled rice bran

2017 ◽  
Vol 41 (3) ◽  
pp. e12353 ◽  
Author(s):  
Manas R. Sahoo ◽  
Sandeep R. Varma ◽  
Neeraj K. Patel ◽  
Thiyagarajan O. Sivaprakasam ◽  
Abheepsa Mishra ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
pp. 5-14 ◽  
Author(s):  
Sandeep R. Varma ◽  
Thiyagarajan O. Sivaprakasam ◽  
Ilavarasu Arumugam ◽  
N. Dilip ◽  
M. Raghuraman ◽  
...  


Author(s):  
Hoda Keshmiri Neghab ◽  
Mohammad Hasan Soheilifar ◽  
Gholamreza Esmaeeli Djavid

Abstract. Wound healing consists of a series of highly orderly overlapping processes characterized by hemostasis, inflammation, proliferation, and remodeling. Prolongation or interruption in each phase can lead to delayed wound healing or a non-healing chronic wound. Vitamin A is a crucial nutrient that is most beneficial for the health of the skin. The present study was undertaken to determine the effect of vitamin A on regeneration, angiogenesis, and inflammation characteristics in an in vitro model system during wound healing. For this purpose, mouse skin normal fibroblast (L929), human umbilical vein endothelial cell (HUVEC), and monocyte/macrophage-like cell line (RAW 264.7) were considered to evaluate proliferation, angiogenesis, and anti-inflammatory responses, respectively. Vitamin A (0.1–5 μM) increased cellular proliferation of L929 and HUVEC (p < 0.05). Similarly, it stimulated angiogenesis by promoting endothelial cell migration up to approximately 4 fold and interestingly tube formation up to 8.5 fold (p < 0.01). Furthermore, vitamin A treatment was shown to decrease the level of nitric oxide production in a dose-dependent effect (p < 0.05), exhibiting the anti-inflammatory property of vitamin A in accelerating wound healing. These results may reveal the therapeutic potential of vitamin A in diabetic wound healing by stimulating regeneration, angiogenesis, and anti-inflammation responses.



Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
J Bauer ◽  
F Dehm ◽  
A Koeberle ◽  
F Pollastro ◽  
G Appendino ◽  
...  


Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
F Epifano ◽  
S Genovese ◽  
L Zhao ◽  
V Dang La ◽  
D Grenier




Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
İ Atay ◽  
AZ İlter ◽  
Y Bağatur ◽  
D Telci ◽  
H Kırmızıbekmez ◽  
...  
Keyword(s):  


Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
S Fuchs ◽  
LT Hsieh ◽  
W Saarberg ◽  
CAJ Erdelmeier ◽  
TA Wichelhaus ◽  
...  
Keyword(s):  


Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
B Michalak ◽  
ME Czerwińska ◽  
AK Kiss


Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
W Peschel ◽  
M Politi ◽  
N Wilson ◽  
A Constanti ◽  
JM Prieto Garcia ◽  
...  
Keyword(s):  


Sign in / Sign up

Export Citation Format

Share Document