Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper‐zinc‐manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split‐face, double‐blinded, randomized, controlled trial

2019 ◽  
Vol 18 (6) ◽  
pp. 1751-1757 ◽  
Author(s):  
Suparuj Lueangarun ◽  
Aphinut Srituravanit ◽  
Therdpong Tempark

2015 ◽  
Vol 60 (5) ◽  
pp. 473 ◽  
Author(s):  
Saeid Nouraei ◽  
Ali Asilian ◽  
Shima Keyvan ◽  
Bahareh Abtahi-Naeini ◽  
Mehrdad Rakhshanpour ◽  
...  


2021 ◽  
pp. 1-9
Author(s):  
Chinathip Theerawattanawit ◽  
Tiwanun Promvaranon ◽  
Pawinee Rerknimitr ◽  
Pravit Asawanonda ◽  
Nopadon Noppakun ◽  
...  

<b><i>Background:</i></b> Ablative fractional carbon dioxide laser (AFCO2) resurfacing causes transient skin barrier disruption characterized by decreased skin hydration and increased transepidermal water loss (TEWL). Snail Soothing and Repairing (SSR) cream, containing several glycoproteins with potential antimicrobial and antioxidant effects, may benefit skin hydration promotion after the laser treatment. <b><i>Objective:</i></b> To evaluate the efficacy and safety of SSR cream in skin hydration promotion after AFCO2 resurfacing. <b><i>Method:</i></b> The study was a double-blinded, split-face, placebo-controlled trial in participants aged 18–50 years with atrophic acne scars on both cheeks. After AFCO2 resurfacing, participants applied the product or placebo on either cheek twice daily for 14 days. Corneometry, TEWL, colorimetry, and clinical assessments (edema, erythema, crusting, pruritus, and tightness score) were evaluated at baseline, day 7, and day 14 after AFCO2 resurfacing. <b><i>Results:</i></b> From 22 participants in the study, the SSR cream-treated sides showed significantly higher corneometry levels than placebo-treated sides at day 14 (<i>p</i> = 0.033), while TEWL and colorimetry levels were not different at any study visits. Pruritus and tightness scores of the SSR side were lower, but not significant, than the placebo. Other clinical assessments (edema, erythema, and crusting) showed similar results. No significant adverse events took place. <b><i>Conclusion:</i></b> The SSR cream significantly improved skin hydration, highlighting skin barrier restoration after AFCO2 resurfacing, with a good safety profile.



2019 ◽  
Vol 58 (10) ◽  
pp. 1212-1222 ◽  
Author(s):  
Rania S. Abou Eitta ◽  
Aisha A. Ismail ◽  
Rania A. Abdelmaksoud ◽  
Naser A. Ghezlan ◽  
Radwa A. Mehanna


2011 ◽  
Vol 37 (11) ◽  
pp. 1700-1703 ◽  
Author(s):  
Nancy Habib ◽  
Nazanin Saedi ◽  
Christopher Zachary




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