Midterm outcomes of transaortic and transapical TAVI in patients with unsuitable vascular anatomy for femoral access: A propensity score inverse probability weight study

2021 ◽  
Vol 36 (3) ◽  
pp. 872-878
Author(s):  
Alberto Pilozzi Casado ◽  
Fabio Barili ◽  
Francesca D'Auria ◽  
Eliana Raviola ◽  
Alessandro Parolari ◽  
...  
Keyword(s):  
Propensity Score ◽  
Vascular Anatomy ◽  
Femoral Access ◽  
Inverse Probability ◽  
Inverse Probability Weight ◽  
Probability Weight

scholarly journals Assessing balance in outcome regressions

2017 ◽  
Author(s):  
Frank Popham ◽  
Alastair Leyland
Keyword(s):  
Matrix Representation ◽  
Causal Effect ◽  
Inverse Probability Weighting ◽  
Probability Weighting ◽  
Sample Mean ◽  
Inverse Probability ◽  
Inverse Probability Weight ◽  
Probability Weight ◽  
The Difference ◽  
Confounder Adjustment

An outcome regression controlling for observed confounders remains a popular way to assess the causal effect of an exposure in epidemiology, despite more modern causal techniques for adjusting for observed confounders, such as inverse probability weighting. A feature of inverse probability weighting is that checking balance of confounders in the control and exposure groups after confounder adjustment is simple. However, researchers using outcome regressions commonly do not check confounder balance after controlling for confounders. Although outcome regressions will balance any confounder specified in the model, the confounder value the model balances at is not transparent. We show that a matrix representation of an outcome regression reveals that an outcome regression includes a weight similar to an inverse probability weight. We also show that outcome regressions may not be balancing at the sample mean of the confounders particularly if interactions are not included with the exposure, which is typically the case in outcome regressions. Finally, we show that the coefficient of the exposure in an outcome regression is simply the difference between two weighted counterfactuals. Thus, there is an important connection between traditional outcome regression and modern causal techniques.

Propensity score trimming mitigates bias due to covariate measurement error in inverse probability of treatment weighted analyses: A plasmode simulation

2021 ◽  
Vol 40 (9) ◽  
pp. 2101-2112
Author(s):  
Mitchell M. Conover ◽  
Kenneth J. Rothman ◽  
Til Stürmer ◽  
Alan R. Ellis ◽  
Charles Poole ◽  
...  
Keyword(s):  
Measurement Error ◽  
Propensity Score ◽  
Inverse Probability ◽  
Covariate Measurement Error

Radial Artery Access for Treatment of Posterior Circulation Aneurysms Using the Pipeline Embolization Device: Case Series

2019 ◽  
Vol 17 (4) ◽  
pp. 340-347 ◽  
Author(s):  
Eytan Raz ◽  
Maksim Shapiro ◽  
Razvan Buciuc ◽  
Peter Kim Nelson ◽  
Erez Nossek
Keyword(s):  
Case Series ◽  
Vascular Anatomy ◽  
Artery Aneurysm ◽  
Posterior Circulation ◽  
Femoral Access ◽  
Pipeline Embolization Device ◽  
Aneurysm Treatment ◽  
Posterior Circulation Aneurysm ◽  
Device Placement ◽  
Posterior Circulation Aneurysms

AbstractBACKGROUNDThe treatment of selected wide-neck and fusiform posterior circulation aneurysms is challenging for clipping as well as for endovascular route.OBJECTIVETo describe an endovascular approach for vertebral artery aneurysm treatment using transradial access (TRA) instead of the conventional transfemoral access.METHODSWe collected cases from two institutions in which TRA was used for posterior circulation Pipeline Embolization Device (Medtronic, Dublin, Ireland) deployment.RESULTSA total of four patients were treated. TRA was useful in the setting of extreme vessel tortuosity. We utilized 5F Terumo Glidesheath (Terumo Medical, Somerset, New Jersey), intermediate catheter, and a 027 microcatheter for Pipeline deployment. TRA was not associated with any access or deployment difficulties.CONCLUSIONSEarly experience suggests that TRA for Pipeline Embolization Device placement for posterior circulation aneurysm is a safe and efficient alternative to standard transfemoral access. While this approach was initially applied to patients with vascular anatomy that may not allow for safe femoral access or navigation, experience so far argues for considering a radial approach towards some posterior circulation aneurysm treatment.

scholarly journals Appraisal of Prognostic Interaction between Sidedness and Mucinous Histology in Colon Cancer: A Population-Based Study Using Inverse Probability Propensity Score Weighting

2019 ◽  
Vol 10 (2) ◽  
pp. 388-396 ◽  
Author(s):  
Zi-Xian Wang ◽  
Lu-Ping Yang ◽  
Hao-Xiang Wu ◽  
Dong-Dong Yang ◽  
Pei-Rong Ding ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Propensity Score ◽  
Population Based ◽  
Population Based Study ◽  
Mucinous Histology ◽  
Inverse Probability ◽  
Propensity Score Weighting

Can pelvic lymph node dissection be omitted in intermediate-risk prostate cancer patients? A SEER-based comparative study using inverse-probability-of-treatment weighting.

2015 ◽  
Vol 33 (7_suppl) ◽  
pp. 95-95 ◽  
Author(s):  
Yu-Wei Chen ◽  
Brandon Arvin Virgil Mahal ◽  
David R. Ziehr ◽  
Michelle Daniel Nezolosky ◽  
Vidya Bhavani Viswanathan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Propensity Score ◽  
Risk Model ◽  
Pelvic Lymph Node Dissection ◽  
Intermediate Risk ◽  
Node Dissection ◽  
Inverse Probability ◽  
Risk Prostate Cancer ◽  
Baseline Characteristics

95 Background: To investigate whether pelvic lymph node dissection (PLND) reduces prostate cancer specific mortality (PCSM) in surgically-treated men with intermediate-risk prostate cancer (Pca). Methods: We identified 44,112 men diagnosed with intermediate-risk Pca from 2004-2009 in Surveillance, Epidemiology and End Results Program (SEER). We used inverse-probability-of-treatment weighting (IPTW) to adjust for baseline characteristics between PLND + radical prostatectomy (RP, N=26,571), versus RP alone (N=17,541) groups; Cox competing-risk model and propensity score-adjusted analyses were used for validation. Gleason scores were based on prostatectomy since biopsy scores were not available for RP-treated patients in SEER from 2004-2009. Results: After a median follow-up of 54 months, there was no survival benefit associated with PLND + RP compared to RP alone (Gray's test, P=0.30). After IPTW adjustment for baseline characteristics, PLND was still not associated with PCSM (AHR: 0.93, 95% CI: 0.65-1.33). This result was consistent with propensity score-adjusted model (AHR=1.05, 95% CI: 0.71-1.55) and the Cox competing-risk model (AHR=1.06, 95% CI: 0.71-1.57). Of men who received RP with PLND, 502 men (1.9%) had pathologically positive lymph nodes, which were associated with a higher risk for PCSM (AHR: 4.02, 95%CI: 1.83-8.84). Conclusions: PLND with RP was not associated with reduced PCSM compared with RP alone in men with intermediate-risk disease, suggesting that PLND is diagnostic but not therapeutic in this patient population. However, a caveat of this study is that risk group was defined by pathologic Gleason score; the 5% of clinically intermediate risk patients who are typically found to have Gleason 8-10 disease at prostatectomy could not be included in this analysis. [Table: see text]

Inverse probability of treatment weighting analysis of upfront surgery versus neoadjuvant chemoradiotherapy followed by surgery for pancreatic adenocarcinoma with arterial abutment.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 440-440
Author(s):  
Tsutomu Fujii ◽  
Suguru Yamada ◽  
Kenta Murotani ◽  
Hideki Takami ◽  
Masamichi Hayashi ◽  
...  
Keyword(s):  
Propensity Score ◽  
Pancreatic Adenocarcinoma ◽  
Odds Ratio ◽  
Survival Rates ◽  
Neoadjuvant Chemoradiotherapy ◽  
Preoperative Imaging ◽  
Borderline Resectable ◽  
Inverse Probability ◽  
Surgery Group ◽  
Clinical Benefits

440 Background: Combined arterial resection during pancreatectomy can be a challenging treatment, and outcome would be more favorable if the tumor becomes technically removable from the artery. Neoadjuvant chemoradiotherapy (NACRT) is expected to achieve locoregional control and enable margin-negative resection. To investigate the effects of NACRT in patients with pancreatic adenocarcinoma (PDAC) which were deemed borderline resectable through preoperative imaging due to abutment of the major artery, including the superior mesenteric artery (SMA) or common hepatic artery (CHA), but were still considered to be technically removable. Methods: Comparisons were make between 71 patients who underwent upfront surgery and 21 patients who underwent NACRT followed by surgery in the strategy to preserve the artery, using unmatched and inverse probability of treatment weighting analysis (UMIN000017115). Results: Fifty patients in the upfront surgery group and 18 in the NACRT group underwent curative resection (70% vs 86%, respectively; P = 0.1609). The results of the propensity score weighted logistic regressions indicated that the incidences of pathological lymph node metastasis and a pathological positive resection margin were significantly lower in the NACRT group (odds ratio, 0.006; P < 0.0001 and odds ratio, 0.007; P = 0.0005, respectively). Among the propensity-score matched patients, the estimated 1- and 2-year survival rates in the upfront surgery group were 66.7% and 16.0%, respectively, and those in the NACRT group were 80.0% and 65.2%, respectively. Conclusions: It was suggested that chemoradiotherapy followed by surgery provided clinical benefits in patients with PDACs in contact with the SMA or CHA. Clinical trial information: 000017115.

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