scholarly journals Estimation of patent foramen ovale size using transcranial Doppler ultrasound in patients with ischemic stroke

2021 ◽  
Author(s):  
Anna Grisold ◽  
Walter Rinner ◽  
Anna Paul ◽  
Harald Gabriel ◽  
Uros Klickovic ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Doppler Ultrasound ◽  
Transcranial Doppler ◽  
Patent Foramen Ovale ◽  
Transcranial Doppler Ultrasound ◽  
Foramen Ovale

Should One Use Echocardiography or Contrast Transcranial Doppler Ultrasound for the Detection of a Patent Foramen Ovale after an Ischemic Cerebrovascular Accident?

2001 ◽  
Vol 12 (4) ◽  
pp. 318-324 ◽  
Author(s):  
Jean-Philippe Baguet ◽  
Gérard Besson ◽  
Frédéric Tremel ◽  
Lionel Mangin ◽  
Christelle Richardot ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Transcranial Doppler ◽  
Cerebrovascular Accident ◽  
Patent Foramen Ovale ◽  
Transcranial Doppler Ultrasound ◽  
Foramen Ovale

Prevalence of patent foramen ovale in subjects with obstructive sleep apnea: a transcranial Doppler ultrasound study

2003 ◽  
Vol 4 (3) ◽  
pp. 219-223 ◽  
Author(s):  
Manolo Beelke ◽  
Silvia Angeli ◽  
Massimo Del Sette ◽  
Carlo Gandolfo ◽  
Maria Eloisa Cabano ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Doppler Ultrasound ◽  
Transcranial Doppler ◽  
Patent Foramen Ovale ◽  
Transcranial Doppler Ultrasound ◽  
Foramen Ovale ◽  
Ultrasound Study ◽  
Obstructive Sleep

scholarly journals A Study on the Relationship Between Patent Foramen Ovale and White Matter Lesions in Migraine Patients

2021 ◽  
Author(s):  
Junyan Huo ◽  
Mengxia Wan ◽  
Nan Li ◽  
Juan Wang ◽  
Xiao Cai ◽  
...  
Keyword(s):  
White Matter ◽  
Transcranial Doppler ◽  
Patent Foramen Ovale ◽  
White Matter Lesions ◽  
Primary Headache ◽  
Transcranial Doppler Ultrasound ◽  
Foramen Ovale ◽  
Significant Difference ◽  
The Difference ◽  
The Relationship

Abstract Background Migraine is a common clinical primary headache with unclear aetiology. In recent years, studies have shown that migraine is related to patent foramen ovale, and some patients with migraine have white matter lesions. However, the relationship among the three is unclear.Objective To explore the characteristics of white matter lesions (WMLs) in migraine patients with patent foramen ovale and to predict the occurrence of patent foramen ovale through magnetic resonance imaging (MRI) characteristics in patients with migraine.Methods Seventy-seven patients clinically diagnosed with migraine were examined by transcranial Doppler ultrasound (cTCD) and MRI. The patients were grouped according to the presence of WMLs, with matching by age, sex, hypertension, diabetes, PFO and other characteristic data. We observed the MRI fluid attenuation inversion recovery sequence (FLAIR) image and compared and analysed the difference in WMLs between the PFO-positive group and the PFO-negative group.Results There were 42 cases and 35 cases of migraine with and without WMLs, respectively. A statistically significant difference in near-cortical WMLs with PFO in migraine patients was observed (P=0.001). Logistic regression analysis adjusted by age, sex, hypertension and diabetes identified PFO status as the sole determinant for the presence of near-cortical WMLs (OR = 0.14; 95%CI 0.045–0.421; p < 0.001)Conclusion Near-cortical white matter lesions in migraine patients are related to PFO. Transcranial Doppler ultrasonography may reveal more PFO in patients with migraine and near-cortical WMLs.

Stroke in Young Military Men With Heterozygous for MTHFR Gene Mutation or Factor V Leiden Gene Mutation Associated With Patent Foramen Ovale: Report of Two Cases and Therapeutic Strategy

2021 ◽  
Author(s):  
Rodrigo Tavares Brisson ◽  
Josevânia Fulgêncio de Lima Arruda ◽  
Liene Duarte Silva ◽  
Dilermando Leal Júnio de Jesus ◽  
Viviane Flumignan Zetola ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Gene Mutation ◽  
Patent Foramen Ovale ◽  
Myocardial Dysfunction ◽  
Factor V Leiden ◽  
Transcranial Doppler Ultrasound ◽  
Mthfr C677t ◽  
Factor V ◽  
Foramen Ovale ◽  
Factor V Leiden Mutation

ABSTRACT We report two cases of Brazilian patients (a 22-year-old male and a 48-year-old male) with ischemic stroke, whose arterial vascular study and echocardiographic investigation did not reveal any steno-occlusive arterial disease or typical cardioembolic finding, such as atrial fibrillation or myocardial dysfunction. A transcranial Doppler ultrasound and a transesophageal echocardiogram showed a patent foramen ovale (PFO), and the laboratory screening for coagulation abnormalities showed heterozygosity for MTHFR C677T and A1298C in one of the patients and heterozygosity for factor V Leiden gene mutations in the other patient. The significance of the association of PFO with Methylenetetrahydrofolate (MTHFR) C677T and A1298C variants or factor V Leiden mutation is discussed as a possible cause of ischemic stroke through paradoxical embolism from a venous source. There is a high prevalence of these two mentioned conditions in the general population, so we discuss two cases in which indication for anticoagulant therapy or percutaneous closure of PFO prevails.

scholarly journals Association Between Patent Foramen Ovale and Overt Ischemic Stroke in Children With Sickle Cell Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Najibah A. Galadanci ◽  
Walter Johnson ◽  
April Carson ◽  
Gerhard Hellemann ◽  
Virginia Howard ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Sickle Cell ◽  
Patent Foramen Ovale ◽  
Contrast Echocardiography ◽  
Transcranial Doppler Ultrasound ◽  
Study Cohort ◽  
Dissemination And Implementation ◽  
Clinical Report ◽  
Foramen Ovale ◽  
Environment Study

Ischemic stroke is one of the most devastating complications of sickle cell anemia (SCA). Previous studies have shown that intracardiac shunting including patent foramen ovale (PFO) can be a potential risk factor for stroke in children with SCA. This study investigates the association between PFO and overt ischemic stroke in the DISPLACE (Dissemination and Implementation of Stroke Prevention Looking at the Care Environment) study cohort of 5,247 children with SCA of whom 1,414 had at least one clinical non-contrast transthoracic echocardiogram. Presence of PFO was taken from the clinical report. Further, we assessed the association between PFO and other clinical and hemolytic factors in children with SCA such as history of abnormal sickle stroke screen [elevated Transcranial Doppler ultrasound (TCD) velocity] and patient's baseline hemoglobin. In 642 children for whom all data were available, the adjusted odds ratio (OR) for overt stroke was higher in those with PFO but this was not statistically significant (OR: 1.49, 95% CI: 0.20–11.03, p = 0.6994). With an OR of 0.85, the study suggested less PFOs in those with abnormal TCD, but this was not statistically significant (95% CI: 0.17–4.25, p = 0.8463). Overall, the prevalence of PFO in this large sub study of non-contrast echocardiography amongst children with SCA is much lower than previous smaller studies using bubble contrast echocardiography. Overt stroke was non-statistically more common in children with SCA and PFO, but there was no evidence that PFO was more common in those with abnormal TCD, the most important pediatric sickle stroke screen.

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