scholarly journals A response surface analysis investigation of the effects of (mis)alignment between interpersonal values and efficacies on interpersonal problems

2021 ◽  
Author(s):  
Madeline Kehl ◽  
Elizabeth A. Edershile ◽  
Christopher J. Hopwood ◽  
Aidan G. C. Wright
2020 ◽  
Author(s):  
Madeline Kehl ◽  
Elizabeth A. Edershile ◽  
Christopher James Hopwood ◽  
Aidan G.C. Wright

Objective: Although the link between mismatched interpersonal values and efficacies and increased interpersonal problems would seem intuitive, previous research has not directly tested this association. This study provides a more comprehensive examination of this relationship than has previously been attempted while also providing a framework through which similar questions regarding intrapersonal mismatches may be investigated. Method: Using scales based in the interpersonal circumplex, we evaluate the values, efficacies and problems of two large samples (undergraduate N=1453, community N=1099), and use response surface analysis to model these variables and their various alignments.Results: We found that there were significant positive relationships between increased mismatches and increased problems in our primary models. We also found that extremity in both matches and mismatches predicted increased problems from the linear trend and that when focusing along an IPC dimension (e.g. warmth), a mismatch of values being greater than efficacies predicted reported problems with the opposite pole of the dimension (e.g., coldness). Conclusion: This study elaborates upon the relationship between values and efficacies, producing results that both align with previous work, and enriching the conceptualization of this relationship via the complexity allowed by the use of RSA.


Author(s):  
Turki Al-Khalifah ◽  
Abdul Aabid ◽  
Sher Afghan Khan ◽  
Muhammad Hanafi Bin Azami ◽  
Muneer Baig

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Patrick Schwarz ◽  
Anne-Laure Bidaud ◽  
Eric Dannaoui

AbstractThe in vitro interactions of isavuconazole with colistin were evaluated against 15 clinical Candida auris isolates by a microdilution checkerboard technique based on the EUCAST reference method for antifungal susceptibility testing and by agar diffusion using isavuconazole gradient concentration strips with or without colistin incorporated RPMI agar. Interpretation of the checkerboard results was done by the fractional inhibitory concentration index and by response surface analysis based on the Bliss model. By checkerboard, combination was synergistic for 93% of the isolates when interpretation of the data was done by fractional inhibitory concentration index, and for 80% of the isolates by response surface analysis interpretation. By agar diffusion test, although all MICs in combination decreased compared to isavuconazole alone, only 13% of the isolates met the definition of synergy. Essential agreement of EUCAST and gradient concentration strip MICs at +/− 2 log2 dilutions was 93.3%. Antagonistic interactions were never observed for any technique or interpretation model used.


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