scholarly journals Microbiologic and Cytologic Assessment of Bronchoalveolar Lavage Fluid from Dogs with Lower Respiratory Tract Infection: 105 Cases (2001-2011)

2013 ◽  
Vol 27 (2) ◽  
pp. 259-267 ◽  
Author(s):  
L.R. Johnson ◽  
E.V. Queen ◽  
W. Vernau ◽  
J.E. Sykes ◽  
B.A. Byrne
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Bronchoalveolar Lavage ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid

Characteristics of bacterial etiology in lower respiratory tract infection: a surveillance report from a Chinese large teaching hospital from 2015 to 2019

2020 ◽  
Author(s):  
Lei Tian ◽  
Zhongju Chen ◽  
Feng He ◽  
Ziyong Sun
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Bacterial Resistance ◽  
Antimicrobial Agents ◽  
Lavage Fluid ◽  
Resistance Rate ◽  
Sputum Culture

Abstract Background: Lower respiratory tract infection (LRI) is a very common clinical disease. The etiological diagnosis of LRI often depends on the result of sputum culture. Sputum is the most common specimen type of LRI in China, but its cultivation result is easily confused by the bacteria colonized in the oral cavity and pharynx. It is very difficult to evaluate the clinical significance of sputum culture results both for clinicians and microbiologists. Fortunately, bronchoscope alveolus lavage fluid(BALF)is a good specimen, whose culture results can accurately reflect the situation of LRI. By analyzing the culture results and antimicrobial agents sensitivity data of BALF accumulated in this area, we can provide reference for clinicians to experience in the treatment of lower respiratory tract infection.Methods: The accumulated data of BALF culture and antimicrobial susceptibility test in our hospital from January 2015 to October 2019 were reviewed and analyzed.Results: The positive rate of BALF culture in our hospital was 18.3% (3467/18935) in 2015-2019. The most common pathogens were Klebsiella pneumoniae (18.1%, 627/3467), Pseudomonas aeruginosa (16.9%, 587/3467) and Acinetobacter baumannii (14.0%, 485/3467). For the eight most common pathogens (K. pneumoniae, P. aeruginosa, A. baumannii, Staphylococcus aureus, Haemophilus influenzae, Stenotrophomonas maltophilia, Escherichia coli and S. pneumoniae), 40-70 years old was the highest age of distribution, but for E. coli and S. pneumoniae, 0-5 years old was also the higher age of distribution. The antibiotic resistance rate of K. pneumoniae to imipenem and meropenem was 30.6% and 30.8%, respectively. The sensitivity of P. aeruginosa to antibiotics other than minocycline and ticarcillin clavulanic acid was all more than 60%. However, the resistance rate of A. baumannii to antibiotics other than tegacyclin and minocycline was all more than 80%.Conclusions: 40-70 years old was the high incidence age of lower respiratory tract bacterial infection. K. pneumoniae resistant to carbapenems (CR-K. pneumoniae) and A. baumannii were a great challenge to clinical treatment and bacterial resistance control.

scholarly journals Microbiota of Bronchoalveolar Lavage Samples from Patients of Lower Respiratory Tract Infection – A Changing Trend

2021 ◽  
Author(s):  
Dhanashree P. Inamdar ◽  
B. Anuradha ◽  
Padmanabh Inamdar ◽  
Poojitha Sai Patti
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Bronchoalveolar Lavage ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Diagnostic Tool ◽  
Lower Respiratory Tract ◽  
Gram Negative ◽  
Sensitivity Pattern ◽  
Tract Infections

Bronchoalveolar lavage (BAL) is the saline wash of the bronchial tree, which aids in diagnosing various pulmonary pathologies. The present study was contemplated with an aim to know the clinical, microbiological profile of BAL samples along with its sensitivity pattern and to assess its utility as a diagnostic tool. This was a prospective observational study, carried over 90 patients presenting with lower respiratory tract infections. The total microbial recovery rate from BAL was 39 (43.3%). The sensitivity, specificity and positive predictive value of BAL were found to be 76.4%, 89.7% and 90.6% respectively. Maximum isolates were bacteria (25.5%) followed by Mycobacterium tuberculosis (MTB) (16.6%) and fungi (1.1%). Predominant bacterial isolates were Gram-negative (81.5%) compared to Gram-positive (18.5%). Multidrug resistance (MDR) in bacteria was seen in 59.2% of isolates. BAL is a valuable diagnostic tool to find not only bacterial but mycobacterial and fungal infections in patients with lower respiratory tract infection (LRTI). A trend towards LRTI with Gram-negative infections is on the rise and they tend to be multidrug-resistant. Hence checking susceptibility patterns is crucial to start evidence-based treatment.

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