Inhibition of Escherichia coli ribosome subunit dissociation by chloramphenicol and Blasticidin: a new mode of action of the antibiotics

2016 ◽  
Vol 64 (1) ◽  
pp. 79-85 ◽  
Author(s):  
B.K. Pathak ◽  
S. Mondal ◽  
C. Barat
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action ◽  
Subunit Dissociation

scholarly journals Electron Microscopic Studies in <i>Escherichia Coli</i> on Mode of Action of Sodium Benzoate and Potassium Sorbate

2019 ◽  
Vol 4 (4) ◽  
pp. 82
Author(s):  
Norma Angélica Santiesteban-López ◽  
Teresa Gladys Cerón-Carrillo ◽  
José Luis Carmona-Silva ◽  
Javier Castro-Rosas
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action ◽  
Sodium Benzoate ◽  
Potassium Sorbate ◽  
Electron Microscopic ◽  
Microscopic Studies

Mode of action of gramicidin S on Escherichia coli membrane

1986 ◽  
Vol 860 (3) ◽  
pp. 608-619 ◽  
Author(s):  
Takashi Katsu ◽  
Hideki Kobayashi ◽  
Yuzaburo Fujita
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action ◽  
Gramicidin S

The Mode of Action of 5-Aza-2'-Deoxycytidine in Escherichia coli

1970 ◽  
Vol 13 (1) ◽  
pp. 180-187 ◽  
Author(s):  
J. Doskocil ◽  
F. Sorm
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action

Mode of action of nisin on Escherichia coli

2020 ◽  
Vol 66 (2) ◽  
pp. 161-168
Author(s):  
Imelda J. Galván Márquez ◽  
Bruce McKay ◽  
Alex Wong ◽  
James J. Cheetham ◽  
Cody Bean ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action ◽  
Genetic Interactions ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Chemical Genetic ◽  
Gram Positive Bacteria ◽  
Knockout Mutants ◽  
Membrane Envelope ◽  
Insight Into

Nisin is a class I polycyclic bacteriocin produced by the bacterium Lactococcus lactis, which is used extensively as a food additive to inhibit the growth of foodborne Gram-positive bacteria. Nisin also inhibits growth of Gram-negative bacteria when combined with membrane-disrupting chelators such as citric acid. To gain insight into nisin’s mode of action, we analyzed chemical–genetic interactions and identified nisin-sensitive Escherichia coli strains in the Keio library of knockout mutants. The most sensitive mutants fell into two main groups. The first group accords with the previously proposed mode of action based on studies with Gram-positive bacteria, whereby nisin interacts with factors involved in cell wall, membrane, envelope biogenesis. We identified an additional, novel mode of action for nisin based on the second group of sensitive mutants that involves cell cycle and DNA replication, recombination, and repair. Further analyses supported these two distinct modes of action.

scholarly journals The use of valinomycin, nigericin and trichlorocarbanilide in control of the protonmotive force in Escherichia coli cells

1983 ◽  
Vol 212 (1) ◽  
pp. 105-112 ◽  
Author(s):  
S Ahmed ◽  
I R Booth
Keyword(s):  
Escherichia Coli ◽  
Membrane Potential ◽  
Mode Of Action ◽  
Ph Gradient ◽  
Protonmotive Force ◽  
Modes Of Action ◽  
Escherichia Coli Cells ◽  
Low Concentrations ◽  
High K ◽  
Specific Control

Valinomycin, nigericin and trichlorocarbanilide were assessed for their ability to control the protonmotive force in Escherichia coli cells. Valinomycin, at high K+ concentrations, was found to decrease the membrane potential delta phi and indirectly to decrease the pH gradient delta pH. Nigericin was found to have two modes of action. At low concentrations (0.05-2 microM) it carried out K+/H+ exchange and decreased delta pH. At higher concentrations (50 microM) it carried out a K+-dependent transfer of H+, decreasing both delta phi and delta pH. In EDTA-treated cells only the latter mode of action was evident, whereas in a mutant sensitive to deoxycholate both types of effect were observed. Trichlorocarbanilide is proposed as an alternative to nigericin for the specific control of delta pH, and it can be used in cells not treated with EDTA.

scholarly journals Synergism of cephalosporins at subinhibitory concentrations and polymorphonuclear leukocytes on phagocytic killing of Escherichia coli and its mode of action.

1986 ◽  
Vol 39 (2) ◽  
pp. 294-303 ◽  
Author(s):  
YUJI WATANABE ◽  
SHUICHI TAWARA ◽  
YASUHIRO MINE ◽  
HIROYUKI KIKUCHI ◽  
SACHIKO GOTO ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action ◽  
Polymorphonuclear Leukocytes ◽  
Subinhibitory Concentrations ◽  
Phagocytic Killing

scholarly journals Structure and mode of action of microcin 7, an antibacterial peptide produced by Escherichia coli.

1985 ◽  
Vol 27 (5) ◽  
pp. 791-797 ◽  
Author(s):  
J F Garcia-Bustos ◽  
N Pezzi ◽  
E Mendez
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action ◽  
Antibacterial Peptide

A protein produced by male strains of Escherichia coli K-12 which increases the yield of recombinants in conjugation: Its nature and mode of action

1973 ◽  
Vol 120 (3) ◽  
pp. 211-226 ◽  
Author(s):  
D. M. Goldfarb ◽  
G. I. Goldberg ◽  
L. S. Chernin ◽  
L. A. Gukova ◽  
I. D. Avdienko ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Mode Of Action ◽  
K 12
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