Primary Hodgkin lymphoma of the central nervous system: Two case reports and review of the literature

2013 ◽  
Vol 33 (6) ◽  
pp. 658-662 ◽  
Author(s):  
Jesse Lee Kresak ◽  
Johnny Nguyen ◽  
Kondi Wong ◽  
Richard Davis
2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Gergely Varga ◽  
Gábor Mikala ◽  
László Gopcsa ◽  
Zoltán Csukly ◽  
Sarolta Kollai ◽  
...  

Central nervous system involvement is a rare complication of multiple myeloma with extremely poor prognosis as it usually fails to respond to therapy. We present 13 cases diagnosed at two centers in Budapest and review the current literature. The majority of our cases presented with high-risk features initially; two had plasma cell leukemia. Repeated genetic tests showed clonal evolution in 3 cases. Treatments varied according to the era, and efficacy was poor as generally reported in the literature. Only one patient is currently alive, with 3-month follow-up, and the patient responded to daratumumab-based treatment. Recent case reports show promising effectivity of pomalidomide and marizomib.


Pathology ◽  
2009 ◽  
Vol 41 (7) ◽  
pp. 649-654 ◽  
Author(s):  
Amina Mekni ◽  
Jihene Kourda ◽  
Karim Ben Hammouda ◽  
Monia Tangour ◽  
Nidhameddine Kchir ◽  
...  

2014 ◽  
Vol 2 (3) ◽  
pp. 88-92 ◽  
Author(s):  
Sarah Alexandra Blydenstein ◽  
Moosa Patel ◽  
Vinitha Philip ◽  
Atul Lakha ◽  
Sugeshnee Pather ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document