Development of More Precise Measurement to Predict Pain 1 Month Postoperatively Based on Use of Acute Postoperative Pain Score in Patients With Distal Radial Fracture

Pain Practice ◽  
2020 ◽  
Vol 20 (7) ◽  
pp. 752-760
Author(s):  
Ryota Imai ◽  
Michihiro Osumi ◽  
Tomoya Ishigaki ◽  
Tomohiko Nishigami ◽  
Yuta Yonemoto ◽  
...  
2010 ◽  
Vol 1 (3) ◽  
pp. 172-172
Author(s):  
Nina Solheim ◽  
Bente Halvorsen ◽  
Leiv Arne Rosseland ◽  
Audun Stubhaug

Abstract Postsurgical inflammation leads to sensitisation of “sleeping” nociceptors, which enhance pain perception and induce hyperalgesia. Prostaglandin E2 plays a central role in this process. Synovial microdialysis technique allows analyses of biological markers of local inflammation simultaneous with a close follow up of the patient’s pain experience. Tissue injury (or surgery) initiates liberation of inflammatory mediators and hyperalgesic substances. This project is translational and aims at exploring the relationship between perceived acute postoperative pain and inflammation. Microdialysis of synovial tissue and pain score after arthroscopy is of special interest to study since the natural pain course and the local inflammation can be observed in patients with no analgesic therapy. Methods This is a clinical observational study of local inflammatory mediators and perceived pain in patients undergoing knee arthroscopy in general anesthesia with propofol, remifentanil and fentanyl. Microdialysis of the synovial membrane was performed in all patients every 20 min for 140 min postoperatively (seven samples). At the same intervals PGE2 was measured and correlated with patients report of pain intensity on a 0–100mm visual analogue scale (VAS). Results Five patients (1 female, 4 male) who did not receive any non-steroidal antiinflammatory drugs or paracetamol were included. The pain intensity was 1–34mmVAS and the PGE2 levels were from 293 pg/ml to 5818 pg/ml. Maximum pain score (mean 23 and SD 12mm VAS) and PGE2 levels (mean 2026 pg/ml and SD 1380 pg/ml) occurred about 40 min after surgery. Correlation analysis shows a significant correlation (R = 0.48, p = 0.004). Conclusion This pilot study indicates a positive correlation between postoperatively perceived pain and local PGE2 concentration.


2019 ◽  
Vol 26 (08) ◽  
pp. 1359-1364
Author(s):  
Sara Jamil ◽  
Rizwan Jouhar ◽  
Dinaz Gandhi ◽  
Tayyaba Tahira ◽  
Jamshed Shaikh

Endodontic Pain if occurs after few hours or days after the treatment indicates a poor pathosis and a bad prognosis in long term, due to this a newer generation of instruments for canal treatment has been introduced from Ni-Ti alloy which has even better ability to shape narrow and curved root canals, without causing aberration. To compare the mean postoperative pain score after manual SS (stainless steel) K-files and mechanical Ni-Ti rotary path files in patients with irreversible pulpitis. Study Design: Randomized controlled trial. Setting: Department of Operative Dentistry, Altamash Institute of Dental Medicine, Karachi. Period: 6 months from 01-10-2017 to 30-03-2018. Materials and Methods: Total 60 patients of irreversible pulpitis with moderate pain score ≥5 were included and divided equally in manual stainless-steel k-files and mechanical Ni-Ti rotary path files groups. Treatment was started with local anesthesia. Patients were recalled after 24 hours and the level of postoperative pain was examined. T-test was applied to compare the outcome in both groups. Stratification was done using t-test and P value ≤0.05 was significantly considered. Results: The mean pre-treatment VAS in group-A and group-B was 7.16±1.44 and 7.86±1.38 respectively. Mean post-treatment VAS in group-A and group-B was 2.33±1.02 and 1.10±0.66 respectively. A significant difference between the pre and post op pain was noted between the two groups, when compared after 24hours by using VAS. Conclusion: Mean post-operative pain score was significantly less with NiTi rotary path files as compare to manual stainless steel K-files.


2007 ◽  
Vol 89 (3) ◽  
pp. 229-232 ◽  
Author(s):  
J Padmanabhan ◽  
A Rohatgi ◽  
A Niaz ◽  
E Chojnowska ◽  
K Baig ◽  
...  

INTRODUCTION The aim of this work was to assess the effect of intermittent bupivacaine infusion into rectus sheath space on postoperative opioid requirement, postoperative pain score and peak expiratory flow rate. PATIENTS AND METHODS A prospective, randomised study involving patients undergoing midline laparotomy. Patients were randomised to receive either intermittent infusion of bupivacaine 0.25% or normal saline via catheters placed in the rectus sheath for 48 h after operation. All patients received intravenous morphine infusion on demand with a patient-controlled analgesic device (PCAD). RESULTS Forty ASA I–III patients were studied. Nineteen were randomised to receive bupivacaine and 21 patients received normal saline. Patient characteristics and surgical variables were comparable in the two groups. The mean wound lengths were similar. There was no statistically significant difference in postoperative opioid requirement, postoperative pain score and peak expiratory flow rate between the two groups. CONCLUSIONS Intermittent bupivacaine infusion into the rectus sheath space after midline laparotomy does not reduce postoperative opioid requirement nor does it affect postoperative pain score or peak expiratory flow rate.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Meiyu Wei ◽  
Ming Liu ◽  
Jie Liu ◽  
Haitao Yang

Aim. This study aims to compare the postoperative analgesia between preoperative and postoperative ultrasound-guided transversus abdominis plane (TAP) blocks for different durations of laparoscopic gynecological surgery. Methods. A total of 120 patients, ASA I-III, 18–65 years of age, were divided randomly into 2 groups: preoperative TAP group (pre-TAP group) and postoperative TAP group (post-TAP group). Patients in the pre-TAP group (n = 60) and post-TAP group (n = 60) received bilateral TAP blocks of 0.375% ropivacaine, 40 mL, preoperatively and postoperatively, respectively. Duration of surgery, postoperative pain score, consumption of analgesics, and postoperative nausea and vomiting (PONV) during the first 24 h postoperatively were recorded. Results. For all the patients in the two groups, similar analgesia was obtained with no statistical difference. The same results were found in duration of surgery <180 min. Meanwhile, patients undergoing surgery >180 min in the post-TAP group obtained lower postoperative pain score, lower analgesics consumption, and higher satisfaction score than those in the pre-TAP group. Conclusion. Postoperative TAP block could offer better postoperative analgesia than preoperative TAP block for patients undergoing surgery >180 min. No difference was found in analgesia effect between preoperative TAP block and postoperative TAP block for patients undergoing surgery <180 min.


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