scholarly journals Bioactive peptides from microalgae. Focus on anti‐cancer and immunomodulating activity

2021 ◽  
Author(s):  
Kari Skjånes ◽  
Reidun Aesoy ◽  
Lars Herfindal ◽  
Hanne Skomedal
2017 ◽  
Vol 5 ◽  
Author(s):  
Jorge L. Díaz-Gómez ◽  
Fabiola Castorena-Torres ◽  
Ricardo E. Preciado-Ortiz ◽  
Silverio García-Lara

2018 ◽  
Vol 88 (5-6) ◽  
pp. 319-343 ◽  
Author(s):  
Elham Nourmohammadi ◽  
Alireza Sadeghi Mahoonak

Abstract. Today, due to immobility, improper food habits, and changes in lifestyle, communities are faced with an increase in health problems such as blood pressure, cholesterol, diabetes, and thrombosis. Bioactive peptides are considered as being the main products of protein hydrolysis which exert high effects on the nervous, immune, and gastrointestinal systems. Unlike synthetic drugs, bioactive peptides have no side effects and this advantage has qualified them as an alternative to such drugs. Due to the above-mentioned properties, this paper focuses on the study of health-improving attributes of bioactive peptides such as anti-oxidative, anti-hypertensive, immunomodulatory, anti-microbial, anti-allergenic, opioid, anti-thrombotic, mineral-binding, anti-inflammatory, hypocholesterolemic, and anti-cancer effects. We also discuss the formation of bioactive peptides during fermentation, the main restrictions on the use of bioactive peptides and their applications in the field of functional foods. In general, food-derived biologically active peptides play an important role in human health and may be used in the development of novel foods with certain health claims.


2017 ◽  
Vol 15 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Jarosław Widelski ◽  
Wirginia Kukula-Koch ◽  
Tomasz Baj ◽  
Bartosz Kedzierski ◽  
Nicolas Fokialakis ◽  
...  

AbstractThe rare coumarins stenocarpin, stenocarpin isobutyrate, oficinalin, oficinalin isobutyrate, 8-methoxypeucedanin and the known xanthotoxin, isoimperatorin, bergapten, peucedanin and 8–methoxyisoimperatorin were isolated from Peucedanum luxurians Tamamsch. (Apiaceae) and identified by means of spectral data (1D and 2D NMR). Their immunomodulating activity was evaluated by flow cytometry and their influence on HL60 cells as well as on PHA-stimulated PBLs was tested. All tested coumarins induce apoptosis (maximal in the 48 h culture) and decrease cell proliferation in a time- and dose-dependent manner, especially in HL60 cells. They also induce partial G1 block, but only in HL60 cells (at 100 µM concentrations). Dose-dependent reduction of RNA content was also found in G1 cells treated by the coumarins. All of the tested coumarins also possessed immunomodulatory activities. Bergapten and xanthotoxin were found to be the best candidates for further evaluation as anti-cancer drugs.


Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki

2010 ◽  
Author(s):  
N. Magnavita ◽  
I. lavicoli ◽  
V. Leso ◽  
A. Bergamaschi

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
S Thamburan ◽  
F February ◽  
M Meyer ◽  
J Rees ◽  
Q Johnson
Keyword(s):  

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
WW Li ◽  
JO Rosa ◽  
MR Siddique ◽  
B Bajana ◽  
J Sulé-Suso ◽  
...  
Keyword(s):  

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