Evaluation of a commercial ELISA for detection of epizootic haemorrhagic disease antibodies in domestic and wild ruminant sera

2020 ◽  
Vol 67 (6) ◽  
pp. 2475-2481
Author(s):  
Emmanuel Bréard ◽  
Cyril Viarouge ◽  
Fabien Donnet ◽  
Corinne Sailleau ◽  
Sophie Rossi ◽  
...  
Keyword(s):  
Wild Ruminant ◽  
Haemorrhagic Disease

Immunity in rabbits experimentally infected with rabbit haemorrhagic disease (RHD) virus

1997 ◽  
Vol 56 (1-3) ◽  
pp. 130
Author(s):  
W Deptuła
Keyword(s):  
Rabbit Haemorrhagic Disease ◽  
Haemorrhagic Disease

A Study of Three Cases of Familial Congenital Hypoprothrombinaemia (Factor II Deficiency)

1964 ◽  
Vol 11 (02) ◽  
pp. 497-505 ◽  
Author(s):  
O de Bastos ◽  
R. S Reno ◽  
O. T Correa
Keyword(s):  
Clotting Factors ◽  
Factor Ii ◽  
Group B ◽  
Haemorrhagic Disease ◽  
Rule Out

SummaryThree cases of true congenital hypoprothrombinaemia are presented.Studies were made to prove the deficiency of prothrombin in the patient’s plasma and to rule out deficiency of other clotting factors or the presence of abnormal anti-thrombin substances.All the patients were of group B.The results obtained confirm that the patients have a real prothrombin deficiency as the cause of a severe haemorrhagic disease.

scholarly journals Haemorrhagic disease and vitamin K.

1987 ◽  
Vol 62 (9) ◽  
pp. 979-979
Author(s):  
B L Priestley
Keyword(s):  
Vitamin K ◽  
Haemorrhagic Disease

scholarly journals Microbial metagenomic approach uncovers the first rabbit haemorrhagic disease virus genome in Sub-Saharan Africa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Anise N. Happi ◽  
Olusola A. Ogunsanya ◽  
Judith U. Oguzie ◽  
Paul E. Oluniyi ◽  
Alhaji S. Olono ◽  
...  
Keyword(s):  
Virus Genome ◽  
Sub Saharan Africa ◽  
High Morbidity ◽  
Vp60 Gene ◽  
Band Size ◽  
Rabbit Haemorrhagic Disease ◽  
Sub Saharan ◽  
Domestic Rabbits ◽  
Haemorrhagic Disease ◽  
Pcr Targeting

AbstractRabbit Haemorrhagic Disease (RHD) causes high morbidity and mortality in rabbits and hares. Here, we report the first genomic characterization of lagovirus GI.2 virus in domestic rabbits from sub-Saharan Africa. We used an unbiased microbial metagenomic Next Generation Sequencing (mNGS) approach to diagnose the pathogen causing the suspected outbreak of RHD in Ibadan, Nigeria. The liver, spleen, and lung samples of five rabbits from an outbreak in 2 farms were analyzed. The mNGS revealed one full and two partial RHDV2 genomes on both farms. Phylogenetic analysis showed close clustering with RHDV2 lineages from Europe (98.6% similarity with RHDV2 in the Netherlands, and 99.1 to 100% identity with RHDV2 in Germany), suggesting potential importation. Subsequently, all the samples were confirmed by RHDV virus-specific RT-PCR targeting the VP60 gene with the expected band size of 398 bp for the five rabbits sampled. Our findings highlight the need for increased genomic surveillance of RHDV2 to track its origin, understand its diversity and to inform public health policy in Nigeria, and Sub-Saharan Africa.

scholarly journals Multivariate Abundance Analysis of Multi-Host/Multi-Parasite Lungworms in a Sympatric Wild Ruminant Population

Diversity ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 227
Author(s):  
Tessa Carrau ◽  
Carlos Martínez-Carrasco ◽  
María Magdalena Garijo ◽  
Francisco Alonso ◽  
Rocío Ruiz de Ybáñez ◽  
...  
Keyword(s):  
Population Level ◽  
Parasite Load ◽  
Fallow Deer ◽  
Host Population ◽  
Marginal Effect ◽  
Wild Ruminant ◽  
Additional Species ◽  
Parasite Abundance ◽  
Associated Risk Factors ◽  
Natural Dynamics

In the analysis of a multi-host/multi-parasite system and its associated risk factors, it is particularly interesting to understand the natural dynamics among pathogens, their hosts, and the environment in wildlife populations. This analysis is particularly feasible in a scenario where multiple overlapping host populations are present in high densities, along with a complex community of parasites. We aimed to describe and analyze the naturally occurring lungworm polyparasitism in a wild ruminant community in Southeast Spain. The respiratory tracts of 250 specimens belonging to four different species (red deer, mouflon, Iberian ibex, and fallow deer) were studied. Almost half (48.0%) of the animals were infected with bronchopulmonary nematodes. Seven different nematodes were identified of which two genera (Protostrongylus spp. and Dictyocaulus spp.) and three additional species (Cystocaulus ocreatus, Muellerius capillaris, and Neostrongylus linearis) were recorded in at least two ruminants, with the mouflon as the commonest host. Our study shows a significant effect of host species and sampling area, plus a marginal effect of age, on parasite multivariate abundance at the host population level. Mouflon and adults of all hosts appear to carry the highest parasite load on average. From a spatial perspective, the highest parasite abundance was detected at the central part of the park.

scholarly journals Sarcoptic mange in wild ruminants in Spain: solving the epidemiological enigma using microsatellite markers

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Barbara Moroni ◽  
Samer Angelone ◽  
Jesús M. Pérez ◽  
Anna Rita Molinar Min ◽  
Mario Pasquetti ◽  
...  
Keyword(s):  
Microsatellite Markers ◽  
Sarcoptes Scabiei ◽  
Host Population ◽  
Sarcoptic Mange ◽  
Wild Ruminant ◽  
Capra Pyrenaica ◽  
Wild Ruminants ◽  
In The Wild ◽  
Genetic Clusters ◽  
Genetic Strains

Abstract Background In Spain, sarcoptic mange was first described in native wildlife in 1987 in Cazorla Natural Park, causing the death of nearly 95% of the local native population of Iberian ibex (Capra pyrenaica). Since then, additional outbreaks have been identified in several populations of ibex and other wild ungulate species throughout the country. Although the first epizootic outbreak in wildlife was attributed to the introduction of an infected herd of domestic goats, the origin and the cause of its persistence remain unclear. The main aims of this study are to understand (i) the number of Sarcoptes scabiei “strains” circulating in wild ruminant populations in Spain, and (ii) the molecular epidemiological relationships between S. scabiei and its hosts. Methods Ten Sarcoptes microsatellite markers were used to characterize the genetic structure of 266 mites obtained from skin scrapings of 121 mangy wild ruminants between 2011 and 2019 from 11 areas in Spain. Results Seventy-three different alleles and 37 private alleles were detected. The results of this study show the existence of three genetic strains of S. scabiei in the wild ruminant populations investigated. While two genetic clusters of S. scabiei were host- and geography-related, one cluster included multi-host mites deriving from geographically distant populations. Conclusions The molecular epidemiological study of S. scabiei in wild ruminants in Spain indicates that the spreading and persistence of the parasite may be conditioned by host species community composition and the permissiveness of each host population/community to the circulation of individual “strains,” among other factors. Wildlife–livestock interactions and the role of human-driven introduction or trade of wild and domestic animals should be better investigated to prevent further spread of sarcoptic mange in as yet unaffected natural areas of the Iberian Peninsula.

A RETRO‐PERITONEAL HÆMATOMA IN HÆMORRHAGIC DISEASE OF THE NEW BORN

1925 ◽  
Vol 1 (7) ◽  
pp. 166-166
Author(s):  
P. L. Hipsley
Keyword(s):  
New Born ◽  
Haemorrhagic Disease

Oral vitamin K1 prevents haemorrhagic disease of the newborn

1995 ◽  
Vol &NA; (1005) ◽  
pp. 16
Author(s):  
&NA;
Keyword(s):  
Vitamin K1 ◽  
Oral Vitamin ◽  
Haemorrhagic Disease

scholarly journals Timing and severity of immunizing diseases in rabbits is controlled by seasonal matching of host and pathogen dynamics

2015 ◽  
Vol 12 (103) ◽  
pp. 20141184 ◽  
Author(s):  
Konstans Wells ◽  
Barry W. Brook ◽  
Robert C. Lacy ◽  
Greg J. Mutze ◽  
David E. Peacock ◽  
...  
Keyword(s):  
Local Population ◽  
Disease Outbreaks ◽  
Maternal Antibodies ◽  
Timing Of Reproduction ◽  
Demographic Rates ◽  
Pathogen Dynamics ◽  
Rabbit Haemorrhagic Disease ◽  
Seasonal Epidemics ◽  
Haemorrhagic Disease

Infectious diseases can exert a strong influence on the dynamics of host populations, but it remains unclear why such disease-mediated control only occurs under particular environmental conditions. We used 16 years of detailed field data on invasive European rabbits ( Oryctolagus cuniculus ) in Australia, linked to individual-based stochastic models and Bayesian approximations, to test whether (i) mortality associated with rabbit haemorrhagic disease (RHD) is driven primarily by seasonal matches/mismatches between demographic rates and epidemiological dynamics and (ii) delayed infection (arising from insusceptibility and maternal antibodies in juveniles) are important factors in determining disease severity and local population persistence of rabbits. We found that both the timing of reproduction and exposure to viruses drove recurrent seasonal epidemics of RHD. Protection conferred by insusceptibility and maternal antibodies controlled seasonal disease outbreaks by delaying infection; this could have also allowed escape from disease. The persistence of local populations was a stochastic outcome of recovery rates from both RHD and myxomatosis. If susceptibility to RHD is delayed, myxomatosis will have a pronounced effect on population extirpation when the two viruses coexist. This has important implications for wildlife management, because it is likely that such seasonal interplay and disease dynamics has a strong effect on long-term population viability for many species.

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