Utilization of multiple SAVI SCOUT surgical guidance system reflectors in the same breast: A single-institution feasibility study

e18002 Background: Most patients with adult ALL eventually relapse. Salvage regimens in these patients and in patients with primary refractory disease are generally based on cytarabine in combination with other agents. Exact merit of each combination remains undefined as these continue to be tested in non randomized trials. This study was conducted with the objectives to find out the efficacy and toxicity of cytarabine and idarubicin combination. Methods: From December 2006 to March 2008, 30 patients were enrolled in this prospective, nonrandomized single institution phase II feasibility study. It was empirically decided that the study will only be considered feasible if more then ten patients achieve a complete remission. Patients who relapsed during maintenance therapy or were refractory and were at least 16-years-old were considered eligible provided they have received at least vincristine and prednisone as induction. No prior cytarabine was allowed. Cytarabine 100 mg/m2 continuous infusion for seven days along with idarubicin 12 mg/m2 day 1 to 3, IV bolus was given. Bone marrow examination was done 15 days after the completion of chemotherapy. Results: All thirty patients completed planned treatment. Five patients died of infection during treatment. Eleven patients achieved complete remission. All patients relapsed within eight months. Conclusions: The regimen of cytrarabine and idarubicin is feasible and sufficiently effective in relapsed or refractory adult ALL with manageable toxicity. No significant financial relationships to disclose.

Download Full-text

A radiofrequency device for tract ablation after liver biopsy: a single-institution human feasibility study

British Journal of Radiology ◽

10.1259/bjr.20170585 ◽

2018 ◽

Vol 91 (1085) ◽

pp. 20170585 ◽

Cited By ~ 1

Author(s):

Kyoung Doo Song ◽

Hyunchul Rhim ◽

Min Woo Lee ◽

Tae Wook Kang ◽

Sanghyeok Lim

Keyword(s):

Liver Biopsy ◽

Feasibility Study ◽

Single Institution

Download Full-text

High-Quality See-Through Surgical Guidance System Using Enhanced 3-D Autostereoscopic Augmented Reality

IEEE Transactions on Biomedical Engineering ◽

10.1109/tbme.2016.2624632 ◽

2017 ◽

Vol 64 (8) ◽

pp. 1815-1825 ◽

Cited By ~ 27

Author(s):

Xinran Zhang ◽

Guowen Chen ◽

Hongen Liao

Keyword(s):

Augmented Reality ◽

Guidance System ◽

High Quality ◽

Surgical Guidance

Download Full-text

Accuracy of a Newly Developed Cone-Beam Computerized Tomography-Aided Surgical Guidance System for Dental Implant Placement: An Ex Vivo Study

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-11-00062 ◽

2012 ◽

Vol 38 (6) ◽

pp. 706-712 ◽

Cited By ~ 3

Author(s):

Sema Murat ◽

Kıvanç Kamburoğlu ◽

Tuncer Özen

Keyword(s):

Dental Implant ◽

Computerized Tomography ◽

Ex Vivo ◽

Simulation Software ◽

Guidance System ◽

Cone Beam ◽

Angular Deviation ◽

Surgical Guidance ◽

Implant Placement ◽

Cone Beam Computerized Tomography

The aim of the present study was to measure the accuracy of the cone-beam computerized tomography (CBCT)- aided StentCad Beyond surgical guidance system and to compare bone-supported and tooth/bone-supported guidance by using this system in dental implant placement ex vivo. Five cadaver mandibles were scanned using an Iluma CBCT scanner. After scanning, DICOM slices were transferred to the StentCad Beyond implant simulation software, which was used for preoperative implant planning. Using the StentCad Beyond guidance system, 9 implant drills were inserted using a bone-supported guidance system and 11 using a tooth/bone-supported guidance system. Mandibles were scanned again and these data were transferred to the StentCad Beyond software. Pre- and postoperative information was superimposed using the Rhinoceros version 4 software program, and deviations between planned and actual drill positions were calculated for each implant. In addition, differences between bone-supported and tooth/bone-supported guidance systems were analyzed by t-test, with a significance level of P < .05. Data analysis found a mean coronal deviation of 1.2 ± 0.3 mm and 0.6 ± 0.6 mm, mean apical deviation of 1.3 ± 0.6 mm and 0.7 ± 0.6 mm, mean apical and coronal depth deviation of 1.4 ± 0.3 mm and 1.3 ± 0.3 mm, and mean angular deviation of 4.2° ± 2.0° and 3.0° ± 1.5° for tooth/bone supported and bone-supported guides, respectively. No statistical differences were found in depth or angular deviations between groups (P > .05); however, statistically significant differences between groups were found in mean horizontal coronal deviation (P = .016) and mean horizontal apical deviation (P = .047). The StentCad Beyond system was found to be a reliable guide for placing implants ex vivo.

Download Full-text