The continued role of intraoperative assessment of the surgical margins in lumpectomy samples

2021 ◽  
Author(s):  
Shahla Masood
Keyword(s):  
Surgical Margins ◽  
Intraoperative Assessment

scholarly journals Role of adjuvant radiation or re-excision for early stage vulvar squamous cell carcinoma with positive or close surgical margins

2019 ◽  
Vol 154 (2) ◽  
pp. 276-279 ◽  
Author(s):  
Sabrina M. Bedell ◽  
Chloe Hedberg ◽  
Anna Griffin ◽  
Hannah Pearson ◽  
Annelise Wilhite ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Surgical Margins ◽  
Adjuvant Radiation ◽  
Vulvar Squamous Cell Carcinoma

Intraoperative assessment of renal and visceral artery reconstruction: The role of duplex scanning and spectral analysis

1987 ◽  
Vol 5 (1) ◽  
pp. 137-147 ◽  
Author(s):  
Steven P. Okuhn ◽  
Linda M. Reilly ◽  
John B. Bennett ◽  
Linda Hughes ◽  
Jerry Goldstone ◽  
...  
Keyword(s):  
Spectral Analysis ◽  
Duplex Scanning ◽  
Visceral Artery ◽  
Intraoperative Assessment ◽  
Artery Reconstruction

682 ROLE OF POSITIVE SURGICAL MARGINS IN PATIENTS WITH ORGAN CONFINED PROSTATE CANCER. IMPLICATIONS FOR ADJUVANT TREATMENTS

2010 ◽  
Vol 9 (2) ◽  
pp. 224
Author(s):  
A. Briganti ◽  
N. Suardi ◽  
U. Capitanio ◽  
M. Freschi ◽  
A. Salonia ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Surgical Margins ◽  
Positive Surgical Margins

scholarly journals Intraoperative assessment of renal and visceral artery reconstruction: The role of duplex scanning and spectral analysis

1987 ◽  
Vol 5 (1) ◽  
pp. 137-147 ◽  
Author(s):  
Steven P. Okuhn ◽  
Linda M. Reilly ◽  
John B. Bennett ◽  
Linda Hughes ◽  
Jerry Goldstone ◽  
...  
Keyword(s):  
Spectral Analysis ◽  
Duplex Scanning ◽  
Visceral Artery ◽  
Intraoperative Assessment ◽  
Artery Reconstruction

scholarly journals The role of surgical margins in atypical Lipomatous Tumours of the extremities

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Jessica Rauh ◽  
Alexander Klein ◽  
Andrea Baur-Melnyk ◽  
Thomas Knösel ◽  
Lars Lindner ◽  
...  
Keyword(s):  
Surgical Margins

scholarly journals Intraoperative Assessment of Surgical Margins of Oral Squamous Cell Carcinoma Using Frozen Sections: A Practical Clinicopathological Management for Recurrences

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Shun Miyota ◽  
Takanori Kobayashi ◽  
Tatsuya Abé ◽  
Hisashi Miyajima ◽  
Masaki Nagata ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Free Group ◽  
Squamous Cell ◽  
Frozen Section ◽  
Surgical Margins ◽  
Clinical Issue ◽  
Intraoperative Assessment ◽  
Relapse Group

Background. Local recurrence remains a challenging clinical issue for the treatment of oral squamous cell carcinoma (SCC). We analyzed retrospectively how effective the frozen section technique (FS) was against recurrences of oral SCC.Methods. We screened 343 surgical samples from 236 patients who had oral SCC, carcinoma in situ (CIS), or epithelial dysplasia, and we followed up their clinical outcomes for at least 5 years. Histopathological states of surgical margins were compared between FS and surgical materials in relapse and relapse-free groups, respectively.Results. Among the 236 patients, 191 were classified into the relapse-free group, and 45 into the relapse group. FS was more frequently performed in the relapse-free group (128/191) than in the relapse group (83/152). Histopathologically, moderate dysplasia or CIS (borderline malignancies) and SCC were recognized in 55 samples of the relapse-free group and in 57 of the relapse group. For those surgical margins with borderline malignancies, additional incisions were performed in 38 of the 55 relapse-free cases, which reduced to 20 from the 38 margins with borderline malignancies (47.4% reduction), and in 39 of the 57 relapse cases, which reduced to only 3 of 39 (7.7% reduction).Conclusions. The intraoperative assessment of surgical margins by FS is essential in preventing recurrences of oral mucosal malignancies.

Ipsilateral breast tumor reappearance in patients treated with conservative surgery after primary chemotherapy. The role of surgical margins on outcome

2006 ◽  
Vol 94 (5) ◽  
pp. 375-379 ◽  
Author(s):  
Oreste Gentilini ◽  
Mattia Intra ◽  
Sara Gandini ◽  
Giulia Peruzzotti ◽  
Erik Winnikow ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Conservative Surgery ◽  
Surgical Margins ◽  
Primary Chemotherapy ◽  
Ipsilateral Breast

Role of breast surgery in T1-T3 breast cancer patients with synchronous bone metastases.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 1115-1115 ◽  
Author(s):  
Edoardo Botteri ◽  
Elisabetta Munzone ◽  
Vincenzo Bagnardi ◽  
Mattia Intra ◽  
Nicole Rotmensz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Bone Metastases ◽  
Breast Surgery ◽  
Treatment Strategies ◽  
Surgical Margins ◽  
Her2 Overexpression ◽  
Breast Cancer Patients ◽  
Ki 67

1115 Background: The role of breast surgery in advanced breast cancer (ABC) is controversial. The main potential advantage of removing the primary tumor is to eliminate the source of further metastatic spread. While previous studies addressed the question in very heterogeneous populations (e.g. patients with any local and distant extension), we have focused on a homogeneous series of ABC patients. Methods: From our institutional Tumor Registry we selected 191 consecutive women diagnosed between 2000 and 2008 with locally operable (T1-T3) ABC, synchronous bone metastases and no other distant sites involved. The progression free survival (PFS) was calculated from diagnosis to the date of progression, defined as either a new site of metastatic disease or clinical/radiographic evidence of increasing tumor burden at a previously known bone metastatic site. Results: Median age was 51 years and 92% of the women had an endocrine-responsive tumor. One-hundred and thirty patients out of 191 (68%) underwent surgery at the time of diagnosis, while 61 (32%) did not. Twenty-six of the operated patients (20%) had previously undergone neoadjuvant chemotherapy; 15 (12%) had positive or undetermined surgical margins. Operated and non-operated patients were similar with respect to age, tumor size, nodal involvement, estrogen and progesterone receptor status, HER2 overexpression and Ki-67, but differed in terms of number of bone metastatic sites: a single metastasis was detected in 34 (26%) operated and 7 (11%) non-operated cases (P=0.02). First-line treatment strategies with endocrine therapy, chemotherapy and Trastuzumab were similarly distributed between the two groups. The 5-year PFS was 22.0% and 10.4% in operated and non-operated patients, respectively. The multi-adjusted hazard ratio was 0.62 (95% confidence interval 0.39-0.98) in favor of surgery. The exclusion of the patients who had received neoadjuvant chemotherapy and patients with positive or undetermined surgical margins did not alter the results. Conclusions: In this large and homogeneous series of ABC patients with synchronous bone metastases, the role of breast surgery had a favorable impact on the progression of the disease, indicating a potential survival benefit.

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