scholarly journals Caregiver socioemotional health as a determinant of child well‐being in school‐aged and adolescent Ugandan children with and without perinatal HIV exposure

2019 ◽  
Vol 24 (5) ◽  
pp. 608-619 ◽  
Author(s):  
Kyle D. Webster ◽  
Miko M. Bruyn ◽  
Sarah K. Zalwango ◽  
Alla Sikorskii ◽  
Jennifer L. Barkin ◽  
...  
2019 ◽  
Vol 33 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Renee Smith ◽  
Yanling Huo ◽  
Katherine Tassiopoulos ◽  
Richard Rutstein ◽  
Suad Kapetanovic ◽  
...  

2016 ◽  
Vol 5 (suppl 1) ◽  
pp. S15-S23 ◽  
Author(s):  
Sharon L. Nichols ◽  
Miriam C. Chernoff ◽  
Kathleen M. Malee ◽  
Patricia A. Sirois ◽  
Steven P. Woods ◽  
...  

2016 ◽  
Vol 35 (6) ◽  
pp. 649-654 ◽  
Author(s):  
Sharon L. Nichols ◽  
Miriam C. Chernoff ◽  
Kathleen Malee ◽  
Patricia A. Sirois ◽  
Paige L. Williams ◽  
...  

2019 ◽  
Vol 220 (5) ◽  
pp. 772-780 ◽  
Author(s):  
Frances M Saccoccio ◽  
Jennifer A Jenks ◽  
Hannah L Itell ◽  
Shuk Hang Li ◽  
Madison Berry ◽  
...  

Abstract Background Development of a cytomegalovirus (CMV) vaccine is a high priority. However, the ability of antibodies to protect against CMV infection is not well characterized. Studies of maternal antibodies in infants offer the potential to identify humoral correlates of protection against postnatal acquisition. Methods This hypothesis-generating study analyzed 29 Ugandan mother-infant pairs that were followed weekly for CMV acquisition. Seventeen mothers and no infants were infected with human immunodeficiency virus (HIV). We evaluated the association between CMV-specific immunoglobulin G (IgG) responses in mothers at the time of delivery and their infants’ CMV status at 6 months of age. We also assessed levels of CMV-specific IgG in infants at 6 weeks of age. CMV-specific IgG responses in the mother-infant pairs were then analyzed on the basis of perinatal HIV exposure. Results We found similar levels of multiple CMV glycoprotein–specific IgG binding specificities and functions in mothers and infants, irrespective of perinatal HIV exposure or infant CMV status at 6 months of age. However, the glycoprotein B–specific IgG titer, measured by 2 distinct assays, was higher in infants without CMV infection and was moderately associated with delayed CMV acquisition. Conclusions These data suggest that high levels of glycoprotein B–specific IgG may contribute to the partial protection against postnatal CMV infection afforded by maternal antibodies, and they support the continued inclusion of glycoprotein B antigens in CMV vaccine candidates.


2015 ◽  
Vol 33 (2) ◽  
pp. 142-149
Author(s):  
Aída de Fátima Thomé Barbosa Gouvêa ◽  
Maria Isabel de Moraes Pinto ◽  
Maristela Miyamoto ◽  
Daisy Maria Machado ◽  
Silvana Duarte Pessoa ◽  
...  

2021 ◽  
Author(s):  
Krystal Cantos ◽  
◽  
Molly F. Franke ◽  
Katherine Tassiopoulos ◽  
Paige L. Williams ◽  
...  

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 81-82
Author(s):  
Taylor Patskanick

Abstract The COVID-19 pandemic has impacted the generations’ health and wellbeing across a range of dimensions. In the first survey, the 50+ adopted the smallest number of health behaviors (e.g., handwashing, mask-wearing, etc.) in response to the pandemic compared to younger age groups. In the first and second surveys, the Baby Boomer generation reported less intense worry than other generations, especially regarding their socioemotional health and family members’ health. For younger generations, worries tended to increase from March to June—especially those related to socio-emotional health and COVID-19 in general. In the third survey wave, older generations self-reported better psychological wellbeing, less personal burnout, and better cognitive health compared to younger generations. Willingness to get the COVID-19 vaccine did not vary by generation in this sample; however, implications of this (including additional factors that may be influential such as psychological wellbeing) will be discussed.


1999 ◽  
Vol 45 (4, Part 2 of 2) ◽  
pp. 163A-163A
Author(s):  
David Hill ◽  
Yvonne A Maldonado ◽  
Barbara Sullivan

2015 ◽  
Vol 2 ◽  
Author(s):  
M. D. Burkey ◽  
S. M. Murray ◽  
P. Bangirana ◽  
I. Familiar ◽  
R. O. Opoka ◽  
...  

Background.Attention-deficit/hyperactivity disorder (ADHD) is among the most commonly diagnosed mental disorders in childhood and is associated with substantial deficits in executive functioning and lost academic and occupational attainment. This study evaluates symptoms of ADHD and their association with neurocognitive deficits in a cohort of rural Ugandan children who were born to HIV-infected mothers.Methods.We assessed ADHD symptoms and executive function (including memory and attention) in a non-clinical sample of children born to HIV-infected mothers in rural eastern Uganda. Analyses included assessments of the psychometric properties, factor structure, and convergent and discriminant validity of the ADHD measure (ADHD-Rating Scale-IV); and executive function deficits in children meeting symptom criteria for ADHD.Results.232 children [54% female; mean age 7.8 years (s.d. 2.0)] were assessed for ADHD and executive function deficits. The ADHD measure showed good internal consistency (α = 0.85.) Confirmatory factor analysis showed an acceptable fit for the diagnostic and statistical manual of mental disorders (DSM-5) two-factor model. Subjects meeting DSM-5 symptom criteria for ADHD had worse parent-rated executive function on six out of seven subscales.Conclusions.Our results demonstrate structural validity of the ADHD measure with this population, strong associations between ADHD symptom severity and poorer executive function, and higher levels of executive function problems in perinatally HIV-exposed Ugandan children with ADHD. These findings suggest that ADHD may be an important neurocognitive disorder associated with executive function problems among children in sub-Saharan African settings where perinatal HIV exposure is common.


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