PJ34, a PARP1 inhibitor, attenuates acute allograft rejection after murine heart transplantation via regulating the CD4 + T lymphocyte response

2020 ◽  
Author(s):  
Xing Chen ◽  
Yajun Huang ◽  
Dashuai Wang ◽  
Nianguo Dong ◽  
Xinling Du
Keyword(s):  
Heart Transplantation ◽  
T Lymphocyte ◽  
Allograft Rejection ◽  
Acute Allograft Rejection ◽  
Lymphocyte Response

scholarly journals Elevated serum concentrations of cardiac troponin T in acute allograft rejection after human heart transplantation

1998 ◽  
Vol 32 (2) ◽  
pp. 405-412 ◽  
Author(s):  
Thomas J Dengler ◽  
Rainer Zimmermann ◽  
Klaus Braun ◽  
Margit Müller-Bardorff ◽  
Jörg Zehelein ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Allograft Rejection ◽  
Cardiac Troponin ◽  
Human Heart ◽  
Troponin T ◽  
Elevated Serum ◽  
Cardiac Troponin T ◽  
Serum Concentrations ◽  
Acute Allograft Rejection

Vor 50 Jahren: Erste erfolgreiche Behandlung einer akuten Herztransplantat-Abstoßungskrise

2018 ◽  
Vol 143 (25) ◽  
pp. 1864-1865
Author(s):  
Walter Land
Keyword(s):  
South Africa ◽  
Heart Transplantation ◽  
Allograft Rejection ◽  
Cardiac Transplantation ◽  
Human Heart ◽  
Immunosuppressive Agent ◽  
Clinical Use ◽  
Antilymphocyte Globulin ◽  
Acute Allograft Rejection ◽  
Success Story

AbstractThe first clinical use of the “Munich antilymphocyte globulin” (ALG) at the occasion of the first successful human heart transplantation is briefly described. The cardiac transplantation was carried out by Christiaan Barnard and his team in Cape Town, South Africa, in 1968. The patient developed an acute allograft rejection which could be successfully reversed within three weeks using the intravenous administration of ALG. This event can be regarded as the beginning of a success story of ALG in its use as a powerful immunosuppressive agent in all categories of clinical organ transplantation.

scholarly journals Effective long-term methotrexate therapy for acute allograft rejection after heart transplantation

1998 ◽  
Vol 31 ◽  
pp. 34-35
Author(s):  
G.M. Mullen ◽  
M.A. Silver ◽  
C.E. Lawless ◽  
J. Mendez ◽  
P.C. Barath ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Allograft Rejection ◽  
Methotrexate Therapy ◽  
Acute Allograft Rejection
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