Is low‐level laser therapy useful as an adjunctive treatment for canine acral lick dermatitis? A randomized, double‐blinded, sham‐controlled study

Introduction. Pemphigus vulgaris is a relatively rare, chronic, autoimmune vesiculobullous disorder characterized by formation of intraepithelial vesiculae and/or bullae in the skin and mucous membrane. Systemic steroids are considered to be the standard first-line therapy for pemphigus vulgaris. However, for patients unresponsive to standard therapy, the new treatment modalities are being sought. Low-level laser therapy has been accepted as an alternative or adjunctive treatment modality for many conditions in medicine and dentistry. Therefore, this study was aimed at presenting the effects of low-level laser therapy in the treatment of pemphigus vulgaris and to emphasize the crucial role of dentists in early recognition and diagnosis of pemphigus vulgaris. Material and Methods. The articles published until May 2013 were obtained from the Medline/PubMed online database, using following search terms and key words: ?laser therapy? and ?pemphigus vulgaris?, ?low-level laser irradiation? and ?pemphigus vulgaris?, ?lasers? and ?pemphigus vulgaris? and ?pemphigus vulgaris?. Results. Low-level laser therapy could result in immediate and significant analgesia and improved wound healing within the observation period and follow-up. Furthermore, a decrease in patients? discomfort as well as the absence of recurrence of the pemphigus vulgaris lesions has been claimed. Conclusion. Even though available literature suggests that low-level laser therapy can be efficiently used in treatment of oral pemphigus vulgaris, either independently or as a part of combined therapy approach, these results should be interpreted with caution since there are no solid evidence-based proofs to provide the guidelines for the treatment of pemphigus vulgaris with low-level laser therapy. Therefore, further long-term randomized controlled clinical studies are necessary in order to give any solid recommendations on the use of low-level laser therapy in the treatment of pemphigus vulgaris.

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Low-level laser therapy: An experimental design for wound management: A case-controlled study in rabbit model

Journal of Cutaneous and Aesthetic Surgery ◽

10.4103/0974-2077.129962 ◽

2014 ◽

Vol 7 (1) ◽

pp. 14 ◽

Cited By ~ 11

Author(s):

HamedGhoddusi Johari ◽

Babak Sabet ◽

Sam Zeraatian ◽

Bita Geramizedeh ◽

Hossein Hodjati ◽

...

Keyword(s):

Experimental Design ◽

Laser Therapy ◽

Rabbit Model ◽

Low Level Laser Therapy ◽

Wound Management ◽

Controlled Study ◽

Low Level ◽

Low Level Laser ◽

Level Laser

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Effects of low-level laser therapy versus soft occlusive splints on mouth opening and surface electromyography in females with temporomandibular dysfunction: A randomized-controlled study

PLoS ONE ◽

10.1371/journal.pone.0258063 ◽

2021 ◽

Vol 16 (10) ◽

pp. e0258063

Author(s):

Tamer Shousha ◽

Mohamed Alayat ◽

Ibrahim Moustafa

Keyword(s):

Laser Therapy ◽

Surface Electromyography ◽

Low Level Laser Therapy ◽

Controlled Study ◽

Low Level ◽

Cell Functions ◽

Splint Therapy ◽

Low Level Laser ◽

Level Laser ◽

Significant Difference

Background Low level lasers have been used as an alternative pain relief therapy for muscle and joint pain, since it induces analgesic, anti-inflammatory, and biomodulation effects of the physiological cell functions. The effectiveness of low-level laser therapy in temporomandibular joint dysfunction (TMD) treatment, however, is not well established. Although Surface electromyography (sEMG) has been suggested as a complementary means in TMD diagnosis, the effect of conservative treatments on muscle activity has not yet been thoroughly correlated with (sEMG) findings. Purpose To assess the efficacy of low-level laser therapy (LLLT) as compared to occlusive splint therapy (OST) on the TMJ opening index (TOI) and sEMG of masticatory muscles. Materials and methods 112 female subjects suffering from unilateral myogenous TMD, aged 21–30 years-old, were recruited and divided into three groups: LLLT; soft occlusive splint therapy OST and a waitlist group as controls. Outcome measures TMJ opening index (TOI), Visual analogue scale (VAS), surface electromyography (sEMG). Results A significant reduction was reported in TOI, VAS and the sEMG within the LLLT and OST groups as well as significant decrease in all outcomes between groups in favor of the LLLT group (P< 0.0001). Meanwhile, there was a weak significant difference within the control group probably attributed to the analgesic. Post-hoc pairwise comparisons between groups [control vs occlusive splints, control vs low-level laser and low-level laser vs occlusive splints] revealed significant differences in the VAS and TOI [P = 0.0001; 95% CI: 0.9–2.2, 1.61–4.01, 0.65–1.96]. Conclusions Findings support an evident short term therapeutic effect of the LLLT on improving VAS, TOI and sEMG in females suffering from myogenous TMD.

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