scholarly journals Transgenic models for molecular and physiological studies in the central nervous system

2003 ◽  
Vol 551 (1) ◽  
pp. 3-3
Author(s):  
H. Gainer
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Transgenic Models ◽  
The Central Nervous System ◽  
Physiological Studies

scholarly journals Transgenic models to assess the pathogenic actions of cytokines in the central nervous system

1997 ◽  
Vol 2 (2) ◽  
pp. 125-129 ◽  
Author(s):  
I L Campbell ◽  
A K Stalder ◽  
C-S Chiang ◽  
R Bellinger ◽  
C J Heyser ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Transgenic Models ◽  
The Central Nervous System

Transgenic Models to Study the Actions of Cytokines in the Central Nervous System

1998 ◽  
Vol 5 (3-4) ◽  
pp. 126-135 ◽  
Author(s):  
Iain L. Campbell ◽  
Anna K. Stalder ◽  
Yvette Akwa ◽  
Axel Pagenstecher ◽  
Valérie C. Asensio
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Transgenic Models ◽  
The Central Nervous System

Effects of Hyperoxia on Lung Utrastructure

1970 ◽  
Vol 28 ◽  
pp. 26-27
Author(s):  
Gladys Harrison
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Light Microscopy ◽  
Oxygen Effects ◽  
Age Dependent ◽  
The Central Nervous System ◽  
The Subject ◽  
Space Age ◽  
Alveolar Septa ◽  
Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

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