A Complete Computational Model of Ultrasound Vibro-Acoustography

Author(s):  
Alison E. Malcolm ◽  
Fernando Reitich ◽  
Jiaqi Yang ◽  
Mostafa Fatemi ◽  
James F. Greenleaf

Ultrasound vibro-acoustography is a novel medical imaging modality that combines the high resolution of high-frequency ultrasound with the speckle-free images obtained using low-frequency methods. This imaging modality relies on the non-linear interaction of two high frequency beams at slightly different frequencies. We describe the physics of ultrasound vibro-acoustography and outline a strategy for its modeling, simulation, and optimal design.

2019 ◽  
Vol 41 (5) ◽  
pp. 251-270 ◽  
Author(s):  
Laurentius O. Osapoetra ◽  
Dan M. Watson ◽  
Stephen A. McAleavey

Measurement of corneal biomechanical properties can aid in predicting corneal responses to diseases and surgeries. For delineation of spatially resolved distribution of corneal elasticity, high-resolution elastography system is required. In this study, we demonstrate a high-resolution elastography system using high-frequency ultrasound for ex-vivo measurement of intraocular pressure (IOP)-dependent corneal wave speed. Tone bursts of 500 Hz vibrations were generated on the corneal surface using an electromagnetic shaker. A 35-MHz single-element transducer was used to track the resulting anti-symmetrical Lamb wave in the cornea. We acquired spatially resolved wave speed images of the cornea at IOPs of 7, 11, 15, 18, 22, and 29 mmHg. The IOP dependence of corneal wave speed is apparent from these images. Statistical analysis of measured wave speed as a function of IOP revealed a linear relation between wave speed and IOP cs = 0.37 + 0.22 × IOP, with the coefficient of determination R2 = 0.86. We also observed depth-dependent variations of wave speed in the cornea, decreasing from anterior toward posterior. This depth dependence is more pronounced at higher IOP values. This study demonstrates the potential of high-frequency ultrasound elastography in the characterization of spatially resolved corneal biomechanical properties.


10.12737/5809 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-2
Author(s):  
Белков ◽  
P. Belkov ◽  
Безуглый ◽  
A. Bezuglyy ◽  
Круглова ◽  
...  

To describe ultrasonographic image of human skin with cellulite, the authors used high-frequency ultrasound visualization of the skin with a frequency of 22 MHz using a system DUB (tpm GmbH Germany). The skin on the thigh in 15 patients with cellulite and in 10 patients in the control group was examined. The differences in thickness and acoustic density of dermis and subcutaneous tissue between the group of patients with cellulite and in control were described. Objective data of high frequency ultrasound allow to quantify morphological and functional parameters of the skin in the dynamics and results of cellulite correction.


Author(s):  
Nalin G. Patel ◽  
Dhruvkumar M. Patel ◽  
Mukundkumar V. Patel ◽  
Maitri M. Patel ◽  
Tanmay R. Patel ◽  
...  

Background: High-frequency ultrasound (HFUS) is a mobile, radiation-free imaging tool for the diagnosis of musculoskeletal disorders. We aim to demonstrate the diagnostic value of dynamic HFUS for undiagnosed lower chest, upper abdomen, and loin pain with this case series. Case series: A cricketer presented with long-standing left-sided dull ache lower chest and upper abdominal pain, aggravated on exertion and leaning forward. His previous laboratory and previous imaging tests were unrevealing. Dynamic HFUS of his left ribs during hooking maneuver demonstrated slipping of the eighth rib over the seventh rib associated with clicking. He also reported tenderness over this region. He was diagnosed as slipping rib syndrome (SRS), and was treated with the eighth nerve block under the HFUS guidance. The second and third cases presented with chronic undiagnosed waxing and waning loin pain despite extensive laboratory and radiological workup. Both patients demonstrated twelfth rib HFUS probe tenderness in sitting position with a specific movement that reproduced the pain during dynamic HFUS study. The diagnosis of twelfth rib syndrome (TRS) was confirmed, and treated successfully with a local intercostal nerve block. Review of the literature: HFUS is the most underutilized imaging tool for the diagnosis of unexplained upper abdominal and lower chest pain syndromes. We identified only a few such reported cases managed with the help of HFUS. Conclusion: The dynamic HFUS is a valuable imaging modality for the undiagnosed lower chest, upper abdominal, or loin pain.


Frequenz ◽  
2001 ◽  
Vol 55 (1-2) ◽  
Author(s):  
Michael Vogt ◽  
Katharina Kaspar ◽  
Peter Altmeyer ◽  
Klaus Hoffmann ◽  
Stephan El Gammal

2008 ◽  
Vol 22 (11) ◽  
pp. 903-908 ◽  
Author(s):  
A Lazarescu

Esophageal disorders are common in the general population and can be associated with significant morbidity. Several new diagnostic techniques for esophageal disorders have become available in recent years. These include capsule pH-metry, high-resolution manometry, impedance combined with either pH-metry or manometry, and high-frequency ultrasound. Capsule pH-metry is useful in children and in patients who cannot tolerate the conventional pH-metry catheter. It has the advantage of not interfering with a patient’s usual meals and activities during the 24 h study. High-resolution manometery is easier to perform and interpret than conventional manometry. This has led to improved diagnosis of various esophageal motility disorders. Impedance measures the movement of liquid and gas in the esophagus. When combined with pH-metry, impedance can confirm that retrograde bolus movement (ie, reflux) is occurring while simultaneously measuring changes in pH levels. It has also highlighted the importance of weakly acidic reflux in patients who do not respond to proton pump inhibitors. Weakly acidic reflux cannot be diagnosed with pH-metry alone. Impedance combined with manometry can determine whether a manometric abnormality leads to abnormal bolus clearance. In the past, this was performed with fluoroscopy, yet impedance is equally effective and does not carry the risk of increased radiation exposure. High-frequency ultrasound is currently a research tool to image the esophageal wall, particulary the two muscle layers, in real time during swallows and at rest. It has broadened our understanding of the pathophysiology of esophageal motility disorders.


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