CFD Based Prediction Method of Thrombus Formation in Shear Flow and Its Validation

2008 ◽  
Author(s):  
Masaaki Tamagawa ◽  
Sho Nagahama
Keyword(s):  
Lattice Boltzmann ◽  
Shear Flows ◽  
Thrombus Formation ◽  
Prediction Method ◽  
Blood Pump ◽  
Rotary Blood Pump ◽  
Step Flow ◽  
Orifice Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Boltzmann Method

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow.

CFD Study of Thrombus Formation on Shear Blood Flows for Developing Prediction Method of Thrombus

2007 ◽  
Author(s):  
Masaaki Tamagawa
Keyword(s):  
Lattice Boltzmann ◽  
Shear Flows ◽  
Thrombus Formation ◽  
Prediction Method ◽  
Rotary Blood Pump ◽  
Step Flow ◽  
Blood Flows ◽  
Orifice Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Boltzmann Method

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow.

Prediction Method of Thrombus Formation Process in Separation and Reattachment Blood Flow Using Lattice Boltzmann Method

2009 ◽  
Author(s):  
Masaaki Tamagawa
Keyword(s):  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Shear Flows ◽  
Thrombus Formation ◽  
Prediction Method ◽  
Rotary Blood Pump ◽  
Step Flow ◽  
Orifice Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Boltzmann Method

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow.

CFD Study of Thrombus Formation on Shear Blood Flows by Using Modified Lattice Boltzmann Method and Thrombus Observation

2008 ◽  
Author(s):  
Masaaki Tamagawa
Keyword(s):  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Shear Flows ◽  
Thrombus Formation ◽  
Prediction Method ◽  
Rotary Blood Pump ◽  
Blood Flows ◽  
Orifice Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Boltzmann Method

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow.

Simulation of Thrombus Formation in Shear Flows Using Lattice Boltzmann Method

2009 ◽  
Vol 33 (8) ◽  
pp. 604-610 ◽  
Author(s):  
Masaaki Tamagawa ◽  
Hiroaki Kaneda ◽  
Miki Hiramoto ◽  
Sho Nagahama
Keyword(s):  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Shear Flows ◽  
Thrombus Formation ◽  
Boltzmann Method

scholarly journals Research on Human Erythrocyte’s Threshold Free Energy for Hemolysis and Damage from Coupling Effect of Shear and Impact Based on Immersed Boundary-Lattice Boltzmann Method

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Zhong Yun ◽  
Chuang Xiang ◽  
Liang Wang
Keyword(s):  
Free Energy ◽  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Coupling Effect ◽  
Threshold Value ◽  
Blood Pump ◽  
Immersed Boundary ◽  
Threshold Limit ◽  
Spring Network Model ◽  
Boltzmann Method

Researches on the principle of human red blood cell’s (RBC) injuring and judgment basis play an important role in decreasing the hemolysis in a blood pump. In the current study, the judgment of hemolysis in a blood pump study was through some experiment data and empirical formula. The paper forms a criterion of RBC’s mechanical injury in the aspect of RBC’s free energy. First, the paper introduces the nonlinear spring network model of RBC in the frame of immersed boundary-lattice Boltzmann method (IB-LBM). Then, the shape, free energy, and time needed for erythrocyte to be shorn in different shear flow and impacted in different impact flow are simulated. Combining existing research on RBC’s threshold limit for hemolysis in shear and impact flow with this paper’s, the RBC’s free energy of the threshold limit for hemolysis is found to be 3.46 × 10 − 15  J. The threshold impact velocity of RBC for hemolysis is 8.68 m/s. The threshold value of RBC can be used for judgment of RBC’s damage when the RBC is having a complicated flow of blood pumps such as coupling effect of shear and impact flow. According to the change law of RBC’s free energy in the process of being shorn and impacted, this paper proposed a judging criterion for hemolysis when the RBC is under the coupling effect of shear and impact based on the increased free energy of RBC.

Simulation of Thrombus Formation Process Using Lattice Boltzmann Method With Consideration of Adhesion Force to Wall

2010 ◽  
Author(s):  
Masaaki Tamagawa
Keyword(s):  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Adhesion Force ◽  
Thrombus Formation ◽  
Artificial Organs ◽  
Physical Parameters ◽  
Physical Factors ◽  
Blood Pumps ◽  
Boltzmann Method ◽  
Rotary Blood Pumps

Recently artificial organs, especially rotary blood pumps, have been developed in the worldwide, but in this development, thrombus occurs in the pumps. In general, the main physical factors of thrombus formation are considered to be shear rate, wall properties for blood’s adhesion. But, there are no proper CFD codes for predicting thrombus formations using physical parameters in shear flows. In this paper, new model for predicting thrombus formation by considering aggregation and adhesion force to the wall by lattice Boltzmann method is proposed, and the trend of thrombus’s adhesion to the wall can be simulated more adequately than that of previous one.

Numerical Simulation on Mean Flow past a Circular Cylinder Based on the Lattice Boltzmann Method

2011 ◽  
Vol 105-107 ◽  
pp. 2307-2310
Author(s):  
Jian Ping Yu ◽  
Shu Rong Yu ◽  
Xing Wang Liu
Keyword(s):  
Circular Cylinder ◽  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Mean Flow ◽  
Experiment Data ◽  
Data Simulation ◽  
Lattice Boltzmann Methods ◽  
Flow Past ◽  
Computational Fluid Dynamics Cfd ◽  
Boltzmann Method

Lattice Boltzmann methods (LBM) have become an alternative to conventional computational fluid dynamics (CFD) methods for various systems. In this paper, flow field of mean flow past a circular cylinder was simulated based on the lattice Boltzmann method. The streamline of air past the cylinder illuminated that the fluid adhere on the boundary and doesn’t separate from the surface of cylinder when Re number less than 5. When Re number equal 40, flow separated to form a pair of recirculating eddies can be observed. With the Re number increasing, the trailing vortex length is growth accordingly. When Re number come up to 80, the trailing vortex begin to shed regularly. This result is consistent with the experiment data. Drag coefficient that fluid act on the surface of cylinder was calculated. The calculated results were same as the experiment data. Simulation indicate that LBM can simulate the vortex taking place and shedding effectively.

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