Effects of Arterial Geometry on Inflow Rate Into Cerebral Aneurysms on Curved Arteries

Mass Transport ◽

Cerebral Aneurysms ◽

Inflow Rate ◽

Atherosclerotic Lesions ◽

Pathobiological studies have demonstrated that atherosclerotic lesions have been found on the wall of saccular cerebral aneurysms [1]. We propose a hypothesis that some of these aneurysms are prevented from rupturing due to the atherosclerotic lesions. It has been presented that mass transport of biochemical species such as LDL and ATP, has some important roles in the development of atherosclerosis. A variety of Computational Fluid Dynamics (CFD) studies of the mass transport has been performed for arteries [2, 3], few studies have however, done for aneurysms.

Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth

Brain Sciences ◽

10.3390/brainsci11040520 ◽

2021 ◽

Vol 11 (4) ◽

pp. 520

Author(s):

Emily R. Nordahl ◽

Susheil Uthamaraj ◽

Kendall D. Dennis ◽

Alena Sejkorová ◽

Aleš Hejčl ◽

...

Keyword(s):

Fluid Dynamics ◽

Kinetic Energy ◽

Swirling Flow ◽

Morphological Changes ◽

Cerebral Aneurysms ◽

Patient Specific ◽

Aneurysm Wall ◽

Aneurysm Growth ◽

Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance within the aneurysm growth history. The present retrospective study investigated four patient-specific aneurysms, once at initial diagnosis and then at follow-up, to analyze hemodynamic and morphological changes. Aneurysm geometries were segmented via the medical image processing software Mimics. The geometries were meshed and a computational fluid dynamics (CFD) analysis was performed using ANSYS. Results showed that major geometry bulk growth occurred in areas of low wall shear stress (WSS). Wall shape remodeling near neck impingement regions occurred in areas with large gradients of WSS and oscillatory shear index. This study found that growth occurred in areas where low WSS was accompanied by high velocity gradients between the aneurysm wall and large swirling flow structures. A new finding was that all cases showed an increase in kinetic energy from the first time point to the second, and this change in kinetic energy seems correlated to the change in aneurysm volume.

Computational fluid dynamics (CFD) using porous media modeling predicts recurrence after coiling of cerebral aneurysms

PLoS ONE ◽

10.1371/journal.pone.0190222 ◽

2017 ◽

Vol 12 (12) ◽

pp. e0190222 ◽

Cited By ~ 7

Author(s):

Yasuyuki Umeda ◽

Fujimaro Ishida ◽

Masanori Tsuji ◽

Kazuhiro Furukawa ◽

Masato Shiba ◽

...

Keyword(s):

Fluid Dynamics ◽

Porous Media ◽

Cerebral Aneurysms ◽

Hemodynamic Assessment of Cerebral Aneurysms Using Computational Fluid Dynamics (CFD) Involving the Establishment of Non-Newtonian Fluid Properties

Journal of Neuroendovascular Therapy ◽

10.5797/jnet.oa.2017-0088 ◽

2018 ◽

Vol 12 (8) ◽

pp. 376-385 ◽

Cited By ~ 1

Author(s):

Katsuhiro Tanaka ◽

Fujimaro Ishida ◽

Kimito Kawamura ◽

Hideki Yamamoto ◽

Daiki Horikawa ◽

...

Keyword(s):

Fluid Dynamics ◽

Newtonian Fluid ◽

Cerebral Aneurysms ◽

Hemodynamic Assessment ◽

Fluid Properties ◽

Acta Neurochirurgica Supplement - Trends in Cerebrovascular Surgery and Interventions ◽

Computational Fluid Dynamics for Cerebral Aneurysms in Clinical Settings

10.1007/978-3-030-63453-7_4 ◽

2021 ◽

pp. 27-32

Author(s):

Fujimaro Ishida ◽

Masanori Tsuji ◽

Satoru Tanioka ◽

Katsuhiro Tanaka ◽

Shinichi Yoshimura ◽

...

Keyword(s):

Fluid Dynamics ◽

Cerebral Aneurysms ◽

Patient Specific ◽

Clinical Settings ◽

Geometry Model ◽

Aneurysm Wall ◽

3D Ct Angiography ◽

Specific Geometry ◽

AbstractHemodynamics is thought to play an important role in the pathogenesis of cerebral aneurysms and recent development of computer technology makes it possible to simulate blood flow using high-resolution 3D images within several hours. A lot of studies of computational fluid dynamics (CFD) for cerebral aneurysms were reported; therefore, application of CFD for cerebral aneurysms in clinical settings is reviewed in this article.CFD for cerebral aneurysms using a patient-specific geometry model was first reported in 2003 and it has been revealing that hemodynamics brings a certain contribution to understanding aneurysm pathology, including initiation, growth and rupture. Based on the knowledge of the state-of-the-art techniques, this review treats the decision-making process for using CFD in several clinical settings. We introduce our CFD procedure using digital imaging and communication in medicine (DICOM) datasets of 3D CT angiography or 3D rotational angiography. In addition, we review rupture status, hyperplastic remodeling of aneurysm wall, and recurrence of coiled aneurysms using the hemodynamic parameters such as wall shear stress (WSS), oscillatory shear index (OSI), aneurysmal inflow rate coefficient (AIRC), and residual flow volume (RFV).