scholarly journals Computational Fluid Dynamics for Cerebral Aneurysms in Clinical Settings

2021 ◽  
pp. 27-32
Author(s):  
Fujimaro Ishida ◽  
Masanori Tsuji ◽  
Satoru Tanioka ◽  
Katsuhiro Tanaka ◽  
Shinichi Yoshimura ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Clinical Settings ◽  
Geometry Model ◽  
Aneurysm Wall ◽  
3D Ct Angiography ◽  
Specific Geometry ◽  
Computational Fluid Dynamics Cfd

AbstractHemodynamics is thought to play an important role in the pathogenesis of cerebral aneurysms and recent development of computer technology makes it possible to simulate blood flow using high-resolution 3D images within several hours. A lot of studies of computational fluid dynamics (CFD) for cerebral aneurysms were reported; therefore, application of CFD for cerebral aneurysms in clinical settings is reviewed in this article.CFD for cerebral aneurysms using a patient-specific geometry model was first reported in 2003 and it has been revealing that hemodynamics brings a certain contribution to understanding aneurysm pathology, including initiation, growth and rupture. Based on the knowledge of the state-of-the-art techniques, this review treats the decision-making process for using CFD in several clinical settings. We introduce our CFD procedure using digital imaging and communication in medicine (DICOM) datasets of 3D CT angiography or 3D rotational angiography. In addition, we review rupture status, hyperplastic remodeling of aneurysm wall, and recurrence of coiled aneurysms using the hemodynamic parameters such as wall shear stress (WSS), oscillatory shear index (OSI), aneurysmal inflow rate coefficient (AIRC), and residual flow volume (RFV).

scholarly journals Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth

2021 ◽  
Vol 11 (4) ◽  
pp. 520
Author(s):  
Emily R. Nordahl ◽  
Susheil Uthamaraj ◽  
Kendall D. Dennis ◽  
Alena Sejkorová ◽  
Aleš Hejčl ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Kinetic Energy ◽  
Swirling Flow ◽  
Morphological Changes ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Aneurysm Wall ◽  
Aneurysm Growth ◽  
Computational Fluid Dynamics Cfd

Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance within the aneurysm growth history. The present retrospective study investigated four patient-specific aneurysms, once at initial diagnosis and then at follow-up, to analyze hemodynamic and morphological changes. Aneurysm geometries were segmented via the medical image processing software Mimics. The geometries were meshed and a computational fluid dynamics (CFD) analysis was performed using ANSYS. Results showed that major geometry bulk growth occurred in areas of low wall shear stress (WSS). Wall shape remodeling near neck impingement regions occurred in areas with large gradients of WSS and oscillatory shear index. This study found that growth occurred in areas where low WSS was accompanied by high velocity gradients between the aneurysm wall and large swirling flow structures. A new finding was that all cases showed an increase in kinetic energy from the first time point to the second, and this change in kinetic energy seems correlated to the change in aneurysm volume.

Experimental and Numerical Flow Visualization in Patient Specific Pre Operative Human Airway Geometry

2011 ◽  
Author(s):  
Mathias Vermeulen ◽  
Cedric Van Holsbeke ◽  
Tom Claessens ◽  
Jan De Backer ◽  
Peter Van Ransbeeck ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Particle Image ◽  
Patient Specific ◽  
Lung Volume Reduction ◽  
Cfd Simulations ◽  
Piv Measurements ◽  
Image Velocimetry ◽  
Specific Geometry ◽  
Computational Fluid Dynamics Cfd ◽  
Human Airways

An experimental and numerical platform was developed to investigate the fluidodynamics in human airways. A pre operative patient specific geometry was used to create an identical experimental and numerical model. The experimental results obtained from Particle Image Velocimetry (PIV) measurements were compared to Computational Fluid Dynamics (CFD) simulations under stationary and pulsatile flow regimes. Together these results constitute the first step in predicting the clinical outcome of patients after lung surgeries such as Lung Volume Reduction.

scholarly journals A Workflow for Patient-Individualized Virtual Angiogram Generation Based on CFD Simulation

2012 ◽  
Vol 2012 ◽  
pp. 1-24 ◽  
Author(s):  
Jürgen Endres ◽  
Markus Kowarschik ◽  
Thomas Redel ◽  
Puneet Sharma ◽  
Viorel Mihalef ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Blood Flow ◽  
Shear Stress ◽  
Cfd Simulation ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Hemodynamic Parameters ◽  
Risk Of Rupture ◽  
Computational Fluid Dynamics Cfd ◽  
Subsequent Comparison

Increasing interest is drawn on hemodynamic parameters for classifying the risk of rupture as well as treatment planning of cerebral aneurysms. A proposed method to obtain quantities such as wall shear stress, pressure, and blood flow velocity is to numerically simulate the blood flow using computational fluid dynamics (CFD) methods. For the validation of those calculated quantities, virtually generated angiograms, based on the CFD results, are increasingly used for a subsequent comparison with real, acquired angiograms. For the generation of virtual angiograms, several patient-specific parameters have to be incorporated to obtain virtual angiograms which match the acquired angiograms as best as possible. For this purpose, a workflow is presented and demonstrated involving multiple phantom and patient cases.

Manufacturing and Computational Fluid Dynamics Modeling of a Patient-Specific Fistula Model

2017 ◽  
Author(s):  
Yang Liu ◽  
Yihao Zheng ◽  
John Pitre ◽  
William Weitzel ◽  
Joseph Bull ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Patient Specific ◽  
Cfd Model ◽  
Dynamics Modeling ◽  
Computational Fluid Dynamics Modeling ◽  
Computational Fluid Dynamics Cfd ◽  
Particle Imaging ◽  
Venous Wall ◽  
Good Agreement

Arteriovenous fistula is the joining of an artery to a vein to create vascular access for dialysis. The failure or maturation of fistula is affected by the vessel wall shear stress (WSS), which is difficult to measure in clinic. A computational fluid dynamics (CFD) model was built to estimate WSS of a patient-specific fistula model. To validate this model, a silicone phantom was manufactured and used to carry out a particle imaging velocimetry (PIV) experiment. The flow field from the PIV experiment shows a good agreement with the CFD model. From the CFD model, the highest WSS (40 Pa) happens near the anastomosis. WSS in the vein is larger than that in the artery. WSS on the outer venous wall is larger than that on the inner wall. The combined technique of additive manufacturing, silicone molding, and CFD is an effective tool to understand the maturation mechanism of a fistula.

scholarly journals Computational fluid dynamics (CFD) using porous media modeling predicts recurrence after coiling of cerebral aneurysms

PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0190222 ◽  
Author(s):  
Yasuyuki Umeda ◽  
Fujimaro Ishida ◽  
Masanori Tsuji ◽  
Kazuhiro Furukawa ◽  
Masato Shiba ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Porous Media ◽  
Cerebral Aneurysms ◽  
Computational Fluid Dynamics Cfd
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