Three-Dimensional In-Vivo Cervical Spine Kinematics: Preliminary Comparison of Fusion Patients and Normal Control Subjects

2009 ◽  
Author(s):  
Colin P. McDonald ◽  
Sukhinder K. Bilkhu ◽  
Victor Chang ◽  
Casey Bachison ◽  
Stephen W. Bartol ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Spinal Fusion ◽  
Normal Control ◽  
Three Dimensional ◽  
The United States ◽  
Disc Disease ◽  
Control Subjects ◽  
Spine Kinematics ◽  
Vertebral Bodies

Degenerative disc disease (DDD) of the cervical spine is a common condition that causes significant pain and disability. Treatment for DDD in 2000 exceeded 110,000 patients in the United States alone [1]. A common treatment option for patients involves removal of the degenerated disc and fusion of the adjacent vertebral bodies. However, previous research has shown that as many as 25–92% of patients treated with fusion have disc degeneration at the adjacent levels within 10 years after surgery [2,3]. It has been hypothesized that this is the result of a change in adjacent vertebral segment motion [4]. However, it is unknown if spinal fusion alters motion at these segments. Thus, the objective of this study was to compare the dynamic, three-dimensional (3D) motion of the cervical spine in normal control subjects and spinal fusion patients.

Artificial Disc Versus Fusion: Effect on Three-Dimensional Dynamic In Vivo Cervical Spine Motion

2011 ◽  
Author(s):  
Colin P. McDonald ◽  
Michael J. McDonald ◽  
Nicole L. Ramo ◽  
Stephen W. Bartol ◽  
Michael J. Bey
Keyword(s):  
Cervical Spine ◽  
Three Dimensional ◽  
Adjacent Segment Degeneration ◽  
Cervical Disc ◽  
Adjacent Segment ◽  
Artificial Disc ◽  
Disc Disease ◽  
Adjacent Disc ◽  
Spine Motion

Intervertebral disc degeneration in the cervical spine is a common condition that often manifests as cervical disc disease, resulting in pain, motor weakness and sensory deficits. The most common surgical treatment strategy involves removal of the diseased disc and fusion of the adjacent vertebrae. Although fusion typically relieves symptoms at the surgical site, evidence of degeneration in the adjacent disc has been reported in 25–92% of patients [1,2]. It has been hypothesized that the progression of adjacent segment degeneration is a result of increased motion at the segments adjacent to the site of fusion [3]. As a response to this proposed mechanism of degeneration, artificial discs were designed with the goals of preserving motion at the operative site and maintaining normal motion in the adjacent segments. However, the extent to which normal adjacent segment motion is maintained in artificial disc patients compared to fusion patients remains unknown. Thus, the objective of this study was to compare the dynamic, three-dimensional (3D) motion of the cervical spine in fusion patients and artificial disc replacement patients.

Three-Dimensional Flexibility Characteristics of the Human Cervical Spine In Vivo

Spine ◽  
1998 ◽  
Vol 23 (2) ◽  
pp. 216-223 ◽  
Author(s):  
Philip McClure ◽  
Sorin Siegler ◽  
Robert Nobilini
Keyword(s):  
Cervical Spine ◽  
Three Dimensional

A cerebral decarboxylase for 5-hydroxytryptophane in humans

1961 ◽  
Vol 16 (6) ◽  
pp. 1050-1054 ◽  
Author(s):  
William Sacks
Keyword(s):  
Intravenous Injection ◽  
Normal Control ◽  
Cerebral Metabolism ◽  
Mental Patient ◽  
Double Dose ◽  
Control Subjects ◽  
Arterial Blood ◽  
Body Tissues

Little or no cerebral decarboxylation of 5-hydroxytryptophane could be found using the in vivo technique developed in this laboratory for determination of human cerebral metabolism. Following intravenous injection of dl-5-hydroxytryptophanecarboxyl-C14 little or no significant venous-arterial C14O2 differences resulted in four normal control subjects and four chronic mental patients. No significant differences were found between the two groups. Levels of arterial blood C14O2 activities showed that 5-hydroxytryptophane was decarboxylated readily by other body tissues. Of four subjects pretreated with 1-benzyl-2-methyl-5-methoxytryptamine (BAS), slightly lowered results occurred with the mental patient pretreated with a double dose of BAS. Submitted on June 19, 1961

Three-dimensional dynamic in vivo motion of the cervical spine: assessment of measurement accuracy and preliminary findings

2010 ◽  
Vol 10 (6) ◽  
pp. 497-504 ◽  
Author(s):  
Colin P. McDonald ◽  
Casey C. Bachison ◽  
Victor Chang ◽  
Stephen W. Bartol ◽  
Michael J. Bey
Keyword(s):  
Cervical Spine ◽  
Measurement Accuracy ◽  
Three Dimensional

Cervical Spine Disc Deformation During In Vivo Three-Dimensional Head Movements

2015 ◽  
Vol 44 (5) ◽  
pp. 1598-1612 ◽  
Author(s):  
William Anderst ◽  
William Donaldson ◽  
Joon Lee ◽  
James Kang
Keyword(s):  
Cervical Spine ◽  
Three Dimensional ◽  
Head Movements

scholarly journals Continuous cervical spine kinematics during in vivo dynamic flexion-extension

2014 ◽  
Vol 14 (7) ◽  
pp. 1221-1227 ◽  
Author(s):  
William J. Anderst ◽  
William F. Donaldson ◽  
Joon Y. Lee ◽  
James D. Kang
Keyword(s):  
Cervical Spine ◽  
Spine Kinematics ◽  
Flexion Extension

scholarly journals Finite element analysis of occlusal splint therapy in patients with bruxism

2019 ◽  
Author(s):  
Seifollah Gholampour ◽  
Hanie Gholampour ◽  
Hamed Khanmohammadi
Keyword(s):  
Maximum Stress ◽  
Initial Conditions ◽  
Three Dimensional ◽  
Occlusal Splint ◽  
Element Analysis ◽  
Jaw Bone ◽  
Maximum Deformation ◽  
Splint Therapy ◽  
Control Subjects

Abstract Background: Bruxism is among the habits considered generally as contributory factors for temporomandibular joint (TMJ) disorders and its etiology is still controversial.Methods: Three-dimensional models of maxilla and mandible and teeth of 37 patients and 36 control subjects were created using in-vivo image data. The maximum values of stress and deformation were calculated in 21 patients six months after using a splint and compared with those in the initial conditions. Results: The maximum stresses in the jaw bone and head of mandible were respectively 4.4 and 4.1 times higher in patients than in control subjects. Similar values for deformation were 5.8 and 4.9, respectively. The maximum stress in the jaw bone and head of mandible decreased six months after splint application by up to 71.0% and 72.8%, respectively. Similar values for the maximum deformation were 80.7% and 78.7%, respectively. Following the occlusal splint therapy, the approximation of maximum deformation to the relevant values in control subjects was about 2.6 times the approximation of maximum stress to the relevant values in control subjects. The maximum stress and maximum deformation occurred in all cases in the head of the mandible and the splint had the highest effectiveness in jaw bone adjacent to the molar teeth. Conclusions: Splint acts as a stress relaxer and dissipates the extra stresses generated as well as the TMJ deformation and deviations due to bruxism. The splint also makes the bilateral and simultaneous loading possible and helps with the treatment of this disorder through regulation of bruxism by creating a biomechanical equilibrium between the physiological loading and the generated stress.

scholarly journals In vivo three-dimensional kinematics of the cervical spine during maximal active head rotation

PLoS ONE ◽  
2019 ◽  
Vol 14 (4) ◽  
pp. e0215357 ◽  
Author(s):  
Jian Kang ◽  
Guangru Chen ◽  
Xu Zhai ◽  
Xijing He
Keyword(s):  
Cervical Spine ◽  
Three Dimensional ◽  
Head Rotation
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