Greyscale and contrast enhanced ultrasonography for characterization of gastric malignant tumors

Aims: To evaluate the utility of grey scale ultrasonography (US) and contrast enhanced ultrasonography (CEUS) for characterization of malignant gastric tumors.Material and methods: The study was conducted prospectively and it included a number of 30 patients with malignant gastric tumors diagnosed through upper tract endoscopy and biopsy: 25 adenocarcinomas, 3 lymphomas, and 2 stromal tumors. All the patients were examined by US, followed immediately by CEUS, using both oral and intravenous contrast agents. CEUS assessed the dynamics of the contrast agent during the arterial phase and the venous phase. The distribution characteristics of the contrast agent inside the region of interest (ROI) were also evaluated. Twenty four patients underwent surgery.Results: Adenocarcinomas presented heterogeneous enhancement with variable pattern, followed by a delayed wash-out in almost all of the situations. Lymphomas presented a variable pattern, intensity and homogeneity of the enhancement, followed by delayed wash-out. Stromal tumors showed early arterial intense and homogenous enhancement followed by moderate wash-out in venous phase.Conclusions: Grey scale US and CEUS are useful methods in characterizing gastric tumors and contribute to a more adequate evaluation of the lesions. The dynamics of the contrast agent may be suggestive for the anatomopathological nature of the tumor. Larger studies will be necessary in order to determine thepractical value of the method.

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Use of Contrast-Enhanced Ultrasonography for the Characterization of Tumor Thrombi in Seven Dogs

Animals ◽

10.3390/ani10091613 ◽

2020 ◽

Vol 10 (9) ◽

pp. 1613

Author(s):

Alessia Cordella ◽

Pascaline Pey ◽

Nikolina Linta ◽

Manuela Quinci ◽

Marco Baron Toaldo ◽

...

Keyword(s):

Color Doppler ◽

Case Series ◽

Arterial Phase ◽

Retrospective Case ◽

Primary Tumors ◽

Contrast Enhanced ◽

Venous Phase ◽

Contrast Enhanced Ultrasonography ◽

Tumor Thrombi

Tumors of adrenal and thyroid glands have been associated with vascular invasions—so-called tumor thrombi, both in humans and dogs. The detection and characterization of venous thrombi is an important diagnostic step in patients with primary tumors for both surgical planning and prognosis. The aim of this study was to describe the use of contrast-enhanced ultrasonography (CEUS) for the characterization of tumor thrombi. Dogs with tumor thrombus who underwent bi-dimensional ultrasound (B-mode US) and CEUS were included. Seven dogs were enrolled in this retrospective case series. On B-mode US, all thrombi were visualized, and vascular distension and thrombus-tumor continuity were seen in three and two cases, respectively. On color Doppler examination, all thrombi were identified, seemed non-occlusive and only two presented vascularity. On CEUS, arterial-phase enhancement and washout in the venous phase were observed in all cases. Non-enhancing areas were identified in the tumor thrombi most likely representing non-vascularized tissue that could potentially be embolized in the lungs after fragmentation of the tumor thrombi. On the basis of these preliminary study, CEUS appeared to be useful for the characterization of malignant intravascular invasion.

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Oral and IV Contrast Enhanced Ultrasonography of the digestive tract â€“ a useful completion of the B-mode examination: a literature review and an exhaustive illustration through images

Medical Ultrasonography ◽

10.11152/mu.2013.2066.171.cnrb ◽

2015 ◽

Vol 17 (1) ◽

pp. 62 ◽

Cited By ~ 3

Author(s):

Cristian Neciu ◽

Radu Badea ◽

Liliana Chiorean ◽

Alexandru Florin Badea ◽

Iulian Opincaru

Keyword(s):

Digestive Tract ◽

Personal Experience ◽

Clinical Context ◽

Lesion Area ◽

Qualitative And Quantitative ◽

Grey Scale ◽

Contrast Enhanced ◽

The Us ◽

Contrast Enhanced Ultrasonography

Contrast enhanced ultrasonography, using IV and/or oral/rectal contrast agents, represents a technical development of the US method, which has proved its applicability in the qualitative and quantitative assessment of the normal and pathological circulatory bed, as well as of the digestive lumen. The use of microbubbles and harmonics opens a new horizon in the detection and characterization of the inflammatory and tumoral conditions of the digestive tract. The interpretation of the data requires corroboration with the grey scale aspect of the examined lesion/area, as well as with the clinical context of the case and the results of other diagnosis techniques. The purpose of this paper is to review the main applications of CEUS in digestive tract pathology by analyzing the significant literature and guidelines in the light of our personal experience and demonstrating it through suggestive images.

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New Aspects Concerning Sulphur Hexafluoride Use As Contrast Agent for Ultrasonographyc Diagnosis

Revista de Chimie ◽

10.37358/rc.17.2.5430 ◽

2017 ◽

Vol 68 (2) ◽

pp. 250-254

Author(s):

Oana Timofte ◽

Gabriela Stefanescu ◽

Elena Gologan ◽

Gheorghe G. Balan ◽

Elena Toader ◽

...

Keyword(s):

Contrast Agent ◽

Focal Liver Lesions ◽

European Federation ◽

Liver Lesions ◽

Sulphur Hexafluoride ◽

Contrast Enhanced ◽

Contrast Enhanced Ultrasonography ◽

Examination Techniques ◽

Malignant Lesions

Introduction of contrast agents as microbubbles and to improve ultrasound examination techniques has increased the rate of detection and characterization of liver lesions. Contrast-enhanced ultrasonography (CEUS) is a relatively new method of exploring the liver and diagnosing focal liver lesions (FLL). The aim of this study is to determine the efficiency of microbubbles used for CEUS in managing patients detected in conventional ultrasonography with FLL. We examined 84 patients with FLL, detected on conventional ultrasonography (US), during October 2012-September 2015. We performed contrast-enhanced ultrasonography, using sulphur hexafluoride as a contrast agent, and contrast-enhanced MRI to set the diagnosis. For 37 patients (44.1%) CEUS showed a malignity pattern of enhancement (according to the EFSUMB - European Federation of Societies for Ultrasound in Medicine and Biology- Guidelines 2012), while for 54 (64.3%) patients MRI set the diagnosis of malignity. CEUS detected fewer malignant lesions than MRI, in 20.1% of the cases MRI set de diagnosis. We need further studies in order to improve the quality of CEUS images and technique.

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