Dynamic Fano resonance and enhanced harmful gas measurement sensitivity in a universal multimode waveguide-microcavity model

2022 ◽  
Vol 61 (06) ◽  
Author(s):  
Xueying Jin ◽  
Huiting Liu ◽  
Xin Xu ◽  
Rui Zhang ◽  
Haojie Xia
2020 ◽  
Author(s):  
Nikolas Hundt

Abstract Single-molecule imaging has mostly been restricted to the use of fluorescence labelling as a contrast mechanism due to its superior ability to visualise molecules of interest on top of an overwhelming background of other molecules. Recently, interferometric scattering (iSCAT) microscopy has demonstrated the detection and imaging of single biomolecules based on light scattering without the need for fluorescent labels. Significant improvements in measurement sensitivity combined with a dependence of scattering signal on object size have led to the development of mass photometry, a technique that measures the mass of individual molecules and thereby determines mass distributions of biomolecule samples in solution. The experimental simplicity of mass photometry makes it a powerful tool to analyse biomolecular equilibria quantitatively with low sample consumption within minutes. When used for label-free imaging of reconstituted or cellular systems, the strict size-dependence of the iSCAT signal enables quantitative measurements of processes at size scales reaching from single-molecule observations during complex assembly up to mesoscopic dynamics of cellular components and extracellular protrusions. In this review, I would like to introduce the principles of this emerging imaging technology and discuss examples that show how mass-sensitive iSCAT can be used as a strong complement to other routine techniques in biochemistry.


Author(s):  
Zilvinas Kancleris ◽  
Gediminas Slekas ◽  
Andrius Kamarauskas ◽  
Dalius Seliuta
Keyword(s):  

Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 3254
Author(s):  
Yuri Hayashi Isayama ◽  
Hugo Enrique Hernández-Figueroa

A generalization of the concept of multimode interference sensors is presented here for the first time, to the best of our knowledge. The existing bimodal and trimodal sensors correspond to particular cases of those interference sensors. A thorough study of the properties of the multimode waveguide section provided a deeper insight into the behavior of this class of sensors, which allowed us to establish new criteria for designing more sensitive structures. Other challenges of using high-order modes within the sensing area of the device reside in the excitation of these modes and the interpretation of the output signal. To overcome these, we developed a novel structure to excite any desired high-order mode along with the fundamental mode within the sensing section, while maintaining a fine control over the power distribution between them. A new strategy to detect and interpret the output signal is also presented in detail. Finally, we designed a high-order sensor for which numerical simulations showed a theoretical limit of detection of 1.9×10−7 RIU, making this device the most sensitive multimode interference sensor reported so far.


2021 ◽  
Vol 53 (8) ◽  
Author(s):  
Xuebo Liu ◽  
Qian Yang ◽  
Kexue Peng ◽  
Baohua Zhang ◽  
Haineng Bai ◽  
...  

2021 ◽  
Vol 503 (4) ◽  
pp. 5984-5996
Author(s):  
Mark D Smith ◽  
Martin Bureau ◽  
Timothy A Davis ◽  
Michele Cappellari ◽  
Lijie Liu ◽  
...  

ABSTRACT Supermassive black hole (SMBH) masses can be measured by resolving the dynamical influences of the SMBHs on tracers of the central potentials. Modern long-baseline interferometers have enabled the use of molecular gas as such a tracer. We present here Atacama Large Millimeter/submillimeter Array observations of the elliptical galaxy NGC 7052 at 0${^{\prime\prime}_{.}}$11 ($37\,$pc) resolution in the 12CO(2-1) line and $1.3\,$ mm continuum emission. This resolution is sufficient to resolve the region in which the potential is dominated by the SMBH. We forward model these observations, using a multi-Gaussian expansion of a Hubble Space Telescope F814W image and a spatially constant mass-to-light ratio to model the stellar mass distribution. We infer an SMBH mass of $2.5\pm 0.3\times 10^{9}\, \mathrm{M_\odot }$ and a stellar I-band mass-to-light ratio of $4.6\pm 0.2\, \mathrm{M_\odot /L_{\odot ,I}}$ (3σ confidence intervals). This SMBH mass is significantly larger than that derived using ionized gas kinematics, which however appears significantly more kinematically disturbed than the molecular gas. We also show that a central molecular gas deficit is likely to be the result of tidal disruption of molecular gas clouds due to the strong gradient in the central gravitational potential.


Author(s):  
Jin Sun ◽  
Zongling Ding ◽  
Yuanqin Yu ◽  
WanZhen Liang

The nonlinear Fano effects on the absorption of hybrid systems composed of a silver nanosphere and an indoline dye molecule have been systematically investigated by the hybrid approach, which combines...


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