Pattern-data preparation method to enhance high-throughput mask fabrication in variable-shaped e-beam writing system

1996 ◽  
Author(s):  
Shigehiro Hara ◽  
Eiji Murakami ◽  
Shunko Magoshi ◽  
Kiyomi Koyama ◽  
Hirohito Anze ◽  
...  
2002 ◽  
Vol 41 (Part 1, No. 9) ◽  
pp. 5835-5840
Author(s):  
Kiminobu Akeno ◽  
Munehiro Ogasawara ◽  
Kenji Ooki ◽  
Toru Tojo ◽  
Ryoichi Hirano ◽  
...  

2019 ◽  
Vol 5 (4) ◽  
pp. 176-183 ◽  
Author(s):  
Lei Jin ◽  
Li Kou ◽  
Yanan Zeng ◽  
Chunguang Hu ◽  
Xiaodong Hu

Abstract Inefficient sample preparation methods hinder the performance of high-throughput single-molecule force spectroscopy (H-SMFS) for viscous damping among reactants and unstable linkage. Here, we demonstrated a sample preparation method for H-SMFS systems to achieve a higher ratio of effective target molecules per sample cell by gas-phase silanization and reactant hydrophobization. Digital holographic centrifugal force microscopy (DH-CFM) was used to verify its performance. The experimental result indicated that the DNA stretching success ratio was improved from 0.89% to 13.5%. This enhanced efficiency preparation method has potential application for force-based DNA stretching experiments and other modifying procedures.


2021 ◽  
Author(s):  
Esther Brakkee ◽  
Marjolein van Huijgevoort ◽  
Ruud Bartholomeus

<p>The 2018-2019 drought in northwestern Europe caused severe damage to a wide range of sectors, and has made clear that even in temperate-climate countries adaptations are needed to cope with increasing future drought frequencies. A crucial component of drought strategies is to monitor the status of groundwater resources. However, providing up-to-date assessments of regional groundwater drought development remains challenging due to the limited quality of available data. We set up a time series modelling-based method for data preparation to map the spatiotemporal development of the 2018-2019 groundwater drought in the southeastern Netherlands, based on a large amount of monitoring data. The data preparation method was evaluated for its usefulness and reliability for groundwater drought studies and prediction. The analysis showed that the 2018-2019 meteorological drought caused extreme groundwater drought throughout the southeastern Netherlands, breaking 30-year records almost everywhere. Drought onset and duration were strongly variable in space. Groundwater drought development appeared to be governed dominantly by the spatial distribution of rainfall and the geological-topographic setting. The time series modelling-based data preparation method was found a useful tool for the given situation to enable a detailed, consistent record of groundwater drought development. The time series simulations were generally found to be reliable; however, the use of time series simulations rather than direct measurement series may bias drought estimations especially at a local scale, and underestimate spatial variability. Finally, time series modelling was also found a promising tool for regional-scale drought nowcasting and prediction. Further development of time-series based validation and simulation methods, combined with accessible and consistent monitoring data, will be valuable to enable better groundwater drought monitoring in the future. </p>


2006 ◽  
Author(s):  
Ho-June Lee ◽  
Dong-Suk Nam ◽  
Sang-Hee Lee ◽  
Hyun-Soo Kim ◽  
Jung-Hoon Lee ◽  
...  

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