Transendoscopic soft-tissue laser ablation in the equine upper respiratory tract

Objective: Infections are an important cause of morbidity and mortality for patients with congenital neutropenia. In the present study, we report on the incidence, type, localization of documented infections, as well as the clinical features and long-term outcome in patients with congenital neutropenia in our clinic. Method: We performed a retrospective chart review of children with neutropenia seen at our hospital from 2000-2018. The data of 15 patients with congenital neutropenia were included in this study. Clinical and laboratory data were analyzed retrospectively using patients’ files and an electronic data system. Results: The median age at diagnosis was 34 months (range, four months- 150 months) and the median follow-up time was 48 months (range, 13-179 months). The leading causes of hospital admission before the establishment of the diagnosis were upper respiratory tract infection in six, pneumonia in four, gingival stomatitis in three and soft tissue infection in two patients. We reached the documented 74 hospitalization episodes and the most common reasons for hospitalization were pneumonia (35%), fever (21%), stomatitis (16%), cutaneous and deep soft tissue infections (12%). Conclusion: The management of infectious complications in children with congenital neutropenia is crucial. Early diagnosis is essential to prevent infections and permanent organ damage. Congenital neutropenia should be suspected in patients with a history of frequent upper respiratory tract infection, and necessary investigations should be performed accordingly. However, it should be kept in mind that the clinical findings of the patients may vary despite having the same mutation.

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Recovery of β-lactamase producing bacteria in pediatric infections

Canadian Journal of Microbiology ◽

10.1139/m87-155 ◽

1987 ◽

Vol 33 (10) ◽

pp. 888-895 ◽

Cited By ~ 3

Author(s):

Itzhak Brook

Keyword(s):

Soft Tissue ◽

Respiratory Tract ◽

Respiratory Tract Infections ◽

Upper Respiratory Tract Infections ◽

Soft Tissue Infections ◽

Upper Respiratory Tract ◽

Pulmonary Infections ◽

Upper Respiratory ◽

Pediatric Infections ◽

Tract Infections

The presence of β-lactamase producing bacteria (βLPB) was investigated in specimens obtained from 1469 children who presented with infections of the skin and soft tissue (648), upper respiratory tract (514), pulmonary sites (137), surgical sites (113), and other (57). Of 4989 bacterial isolates recovered, 910 (18%) were βLPB, 492 (54%) aerobes, and 418 (46%) anaerobes. The βLPB were recovered in 751 (51%) of the children. The most frequently recovered βLPB was Staphylococcus aureus, which was recovered in 356 (47%) patients. Most isolates were recovered from patients with skin and soft-tissue infections (68% of patients), upper respiratory tract infections (49%), and pulmonary infections (35%). Bacteroides fragilis group was isolated in 35% of patients with βLPB, mostly from surgical infections (98% of patients), pulmonary infections (36%), skin and soft-tissue infections (25%), and upper respiratory tract infections (20%). Twenty-five percent of the Bacteroides melaninogenicus group produced β-lactamase. These organisms were recovered in 15% of patients with βLPB. They were recovered in upper respiratory tract infections (38% of patients), pulmonary infections (22%), and skin and soft-tissue infections (7%). Other βLPB were Pseudomonas aeruginosa (8% of total patients with βLPB), Escherichia coli (4%), Bacteroides oralis (3%), Klebsiella pneumoniae (3%), Haemophilus influenzae (2%), Proteus (1%), and Branhamella catarrhalis (1%). The role of βLPB in the failure of penicillin to eradicate many of the infections is discussed.

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Pathology Consultation Solitary Fibrous Tumor

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949310200114 ◽

1993 ◽

Vol 102 (1) ◽

pp. 74-76 ◽

Cited By ~ 27

Author(s):

John G. Batsakis ◽

Roger D. Hybels ◽

Adel K. El-Naggar

Keyword(s):

Soft Tissue ◽

Respiratory Tract ◽

Solitary Fibrous Tumor ◽

Surgical Excision ◽

Upper Respiratory Tract ◽

Solitary Fibrous Tumors ◽

Histopathologic Diagnosis ◽

Pleural Neoplasm ◽

Upper Respiratory ◽

Fibrous Tumor

First described as a pleural neoplasm, the solitary fibrous tumor has been reported in a number of extrapleural sites, including the upper respiratory tract. The neoplasm is of mesenchymal origin, exists in benign and malignant forms, and is a histopathologic diagnosis made after exclusion of other soft tissue neoplasms. None of the eight reported sinonasal and nasopharyngeal solitary fibrous tumors have been histologically or biologically malignant. Surgical excision appears to control the tumor at these sites.

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