Pathology Consultation Solitary Fibrous Tumor

1993 ◽  
Vol 102 (1) ◽  
pp. 74-76 ◽  
Author(s):  
John G. Batsakis ◽  
Roger D. Hybels ◽  
Adel K. El-Naggar
Keyword(s):  
Soft Tissue ◽  
Respiratory Tract ◽  
Solitary Fibrous Tumor ◽  
Surgical Excision ◽  
Upper Respiratory Tract ◽  
Solitary Fibrous Tumors ◽  
Histopathologic Diagnosis ◽  
Pleural Neoplasm ◽  
Upper Respiratory ◽  
Fibrous Tumor

First described as a pleural neoplasm, the solitary fibrous tumor has been reported in a number of extrapleural sites, including the upper respiratory tract. The neoplasm is of mesenchymal origin, exists in benign and malignant forms, and is a histopathologic diagnosis made after exclusion of other soft tissue neoplasms. None of the eight reported sinonasal and nasopharyngeal solitary fibrous tumors have been histologically or biologically malignant. Surgical excision appears to control the tumor at these sites.

scholarly journals A Rare Case of a Solitary Fibrous Tumor of the Spermatic Cord

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Moyosore Awobajo ◽  
Stefanie Hettwer ◽  
Sarah Hackman
Keyword(s):  
Solitary Fibrous Tumor ◽  
Spermatic Cord ◽  
Rare Case ◽  
Surgical Excision ◽  
Mesenchymal Tumors ◽  
Solitary Fibrous Tumors ◽  
Important Differential Diagnosis ◽  
History Of ◽  
Scrotal Swelling ◽  
Fibrous Tumor

Solitary fibrous tumors (SFTs) are rare mesenchymal tumors, originally identified in the pleura. Even though they have subsequently been described in several extrapleural sites, the incidence of SFTs in the spermatic cord is particularly rare. Here, we report a case of a 27-year-old male that presented with a 3-year history of left scrotal swelling. Computed tomography (CT) and ultrasound demonstrated multiple solid, hypoechoic well-circumscribed masses that were separate from the testis. Surgical excision of the mass led to pathologic diagnosis of a solitary fibrous tumor involving the spermatic cord. Solitary fibrous tumors, although rare, are an important differential diagnosis for urogenital tumors.

scholarly journals Congenital Neutropenia in Children: Evaluation of Infectious Complications, Treatment Results and Long-Term Outcome

2021 ◽  
Author(s):  
Işık Odaman Al ◽  
Yeşim Oymak ◽  
Tuba Hİlkay Karapınar ◽  
Melek Erdem ◽  
Salih Gözmen ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Infectious Complications ◽  
Upper Respiratory Tract ◽  
Congenital Neutropenia ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Upper Respiratory

Objective: Infections are an important cause of morbidity and mortality for patients with congenital neutropenia. In the present study, we report on the incidence, type, localization of documented infections, as well as the clinical features and long-term outcome in patients with congenital neutropenia in our clinic. Method: We performed a retrospective chart review of children with neutropenia seen at our hospital from 2000-2018. The data of 15 patients with congenital neutropenia were included in this study. Clinical and laboratory data were analyzed retrospectively using patients’ files and an electronic data system. Results: The median age at diagnosis was 34 months (range, four months- 150 months) and the median follow-up time was 48 months (range, 13-179 months). The leading causes of hospital admission before the establishment of the diagnosis were upper respiratory tract infection in six, pneumonia in four, gingival stomatitis in three and soft tissue infection in two patients. We reached the documented 74 hospitalization episodes and the most common reasons for hospitalization were pneumonia (35%), fever (21%), stomatitis (16%), cutaneous and deep soft tissue infections (12%). Conclusion: The management of infectious complications in children with congenital neutropenia is crucial. Early diagnosis is essential to prevent infections and permanent organ damage. Congenital neutropenia should be suspected in patients with a history of frequent upper respiratory tract infection, and necessary investigations should be performed accordingly. However, it should be kept in mind that the clinical findings of the patients may vary despite having the same mutation.

Extrapleural Solitary Fibrous Tumor of the Foot

2015 ◽  
Vol 105 (6) ◽  
pp. 557-559
Author(s):  
Charles A. Kean ◽  
Bridget R. Moore ◽  
Ashley M. Nettles ◽  
Richard P. Bui
Keyword(s):  
Solitary Fibrous Tumor ◽  
Surgical Excision ◽  
Solitary Fibrous Tumors ◽  
Mesenchymal Neoplasms ◽  
Complete Surgical Excision ◽  
Rare Manifestation ◽  
Painless Mass ◽  
Fibrous Tumor ◽  
Extrapleural Solitary Fibrous Tumor ◽  
Male Veteran

Solitary fibrous tumors are uncommon mesenchymal neoplasms that were initially described as pleural tumors, but in recent years, numerous extrapleural sites have been reported. A solitary fibrous tumor is characterized as a circumscribed, painless mass with a patternless growth pattern, positive CD34 spindle-shaped cells, bcl-2, and dense keloidal collagen with areas of hypercellularity and hypocellularity. This case report describes a 55-year-old male veteran who presented with a rare manifestation of an extrapleural solitary fibrous tumor of the medial right hallux. Microscopic and immunohistochemical findings were consistent with the previously documented characteristics of solitary fibrous tumors. Complete surgical excision of the tumor is the treatment of choice.

Extramedullary Plasmacytomata of the Upper Respiratory Tract

1973 ◽  
Vol 82 (5) ◽  
pp. 709-715 ◽  
Author(s):  
J. B. Booth ◽  
A. D. Cheesman ◽  
N. H. Vincenti
Keyword(s):  
Electron Microscopy ◽  
Respiratory Tract ◽  
Serum Proteins ◽  
Surgical Excision ◽  
Upper Respiratory Tract ◽  
Erythrocyte Sedimentation ◽  
Presymptomatic Stage ◽  
Localized Disease ◽  
Upper Respiratory ◽  
Endothelial Tissue

Extramedullary plasmacytomata may arise in any structure containing re-ticulo-endothelial tissue. Such tumors may be either isolated or the initial lesion of a generalized disseminated condition. Ideally, multiple involvement should be diagnosed at the presymptomatic stage; this may be possible by detecting variations in the immunoglobulins. Histologically, electron microscopy is advised to detect the plasma cell in the more undifferentiated case. Nine cases are reported. Two cases showed multiple involvement presenting with extramedullary plasmacytomata. A further case recurred locally many times but is still alive after 22 years. The remaining seven cases showed only isolated extramedullary plasmacytomata; of these, five were benign but in two, the tumor eroded bone locally. Those which subsequently developed multiple myelomata showed changes in the serum proteins, erythrocyte sedimentation rate (ESR) and radiologically, at approximately the same time. Surgical excision and/or radiotherapy was equally successful in those patients with localized disease.

scholarly journals Soliter fibrous tumor of diaphragm in a patient with larynx cancer: Case report

2021 ◽  
Vol 5 (1) ◽  
pp. 001-003
Author(s):  
Arabaci Bengisu ◽  
Ceylan Kenan Can ◽  
Ermete Sulun ◽  
Kilic Devrim ◽  
Kaya Seyda Ors
Keyword(s):  
Case Report ◽  
Male Patient ◽  
Laryngeal Cancer ◽  
Solitary Fibrous Tumor ◽  
Large Volume ◽  
Surgical Excision ◽  
Larynx Cancer ◽  
Cancer Case ◽  
Solitary Fibrous Tumors ◽  
Fibrous Tumor

Introduction: Solitary fibrous tumor is a neoplasm of mesenchymal origin with benign and malignant forms. We aimed to present a case of solitary fibrous tumor which developed in a patient operated for laryngeal cancer and originated from diaphragm in the light of the literature. Case report: A 61-year-old male patient with tracheostomy with an undiagnosed lesion that appears to be almost 10 cm was referred to our clinic. Since it was a large volume mass, we chose to perform a thoracotomy over thorachoscopic approach. Discussion: Although solitary fibrous tumors most commonly occur in the pleura but may also originated from diaphragm, and our case is valuable that originates from diaphragmatic since there are less than 5 reported cases in literature for past two decades. Conclusion: Even in the case of recurrence, the main treatment remains as total surgical excision. Solitary fibrous tumors are usually detected because of compression symptoms. That is the main reason why we chose thoracotomy.

Transendoscopic soft-tissue laser ablation in the equine upper respiratory tract

1997 ◽  
Author(s):  
K. E. Bartels ◽  
C. G. MacAllister ◽  
D. T. Dickey ◽  
S. A. Schafer ◽  
R. E. Nordquist
Keyword(s):  
Laser Ablation ◽  
Soft Tissue ◽  
Respiratory Tract ◽  
Upper Respiratory Tract ◽  
Upper Respiratory

Recovery of β-lactamase producing bacteria in pediatric infections

1987 ◽  
Vol 33 (10) ◽  
pp. 888-895 ◽  
Author(s):  
Itzhak Brook
Keyword(s):  
Soft Tissue ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Upper Respiratory Tract Infections ◽  
Soft Tissue Infections ◽  
Upper Respiratory Tract ◽  
Pulmonary Infections ◽  
Upper Respiratory ◽  
Pediatric Infections ◽  
Tract Infections

The presence of β-lactamase producing bacteria (βLPB) was investigated in specimens obtained from 1469 children who presented with infections of the skin and soft tissue (648), upper respiratory tract (514), pulmonary sites (137), surgical sites (113), and other (57). Of 4989 bacterial isolates recovered, 910 (18%) were βLPB, 492 (54%) aerobes, and 418 (46%) anaerobes. The βLPB were recovered in 751 (51%) of the children. The most frequently recovered βLPB was Staphylococcus aureus, which was recovered in 356 (47%) patients. Most isolates were recovered from patients with skin and soft-tissue infections (68% of patients), upper respiratory tract infections (49%), and pulmonary infections (35%). Bacteroides fragilis group was isolated in 35% of patients with βLPB, mostly from surgical infections (98% of patients), pulmonary infections (36%), skin and soft-tissue infections (25%), and upper respiratory tract infections (20%). Twenty-five percent of the Bacteroides melaninogenicus group produced β-lactamase. These organisms were recovered in 15% of patients with βLPB. They were recovered in upper respiratory tract infections (38% of patients), pulmonary infections (22%), and skin and soft-tissue infections (7%). Other βLPB were Pseudomonas aeruginosa (8% of total patients with βLPB), Escherichia coli (4%), Bacteroides oralis (3%), Klebsiella pneumoniae (3%), Haemophilus influenzae (2%), Proteus (1%), and Branhamella catarrhalis (1%). The role of βLPB in the failure of penicillin to eradicate many of the infections is discussed.

scholarly journals Solitary fibrous tumor: molecular hallmarks and treatment for a rare sarcoma

2021 ◽  
Author(s):  
Alannah Smrke ◽  
Khin Thway ◽  
Paul H Huang ◽  
Robin L Jones ◽  
Andrew J Hayes
Keyword(s):  
Soft Tissue ◽  
Solitary Fibrous Tumor ◽  
Standard Treatment ◽  
Surgical Excision ◽  
Mitotic Rate ◽  
Antiangiogenic Treatment ◽  
Differential Behavior ◽  
Localized Disease ◽  
Fibrous Tumor ◽  
Distinct Subtype

Solitary fibrous tumor (SFT) is a rare soft tissue sarcoma subtype which mainly affects adults in the fifth and sixth decades of life. Originally part of a spectrum of tumors called hemangiopericytomas, classification has been refined such that SFTs now represent a distinct subtype. The identification of NAB2-STAT6 fusion in virtually all SFTs has further aided to define this rare subgroup. SFTs have a spectrum of behavior from benign to malignant, with evidence suggesting risk of metastases related to age at diagnosis, extent of necrosis, mitotic rate and tumor size. The standard treatment for localized disease is surgical excision with or without radiotherapy. Retrospective and prospective evidence suggests antiangiogenic treatment is effective for unresectable disease. Further translational work is required to understand the biology driving the differential behavior and identify more effective treatments for patients with metastatic disease.

Pierre-Marie-Bamberger syndrome and solitary fibrous tumor: a rare association

2018 ◽  
Vol 26 (2) ◽  
pp. 154-157 ◽  
Author(s):  
Estefanía Boyer-Duck ◽  
Walid Leonardo Dajer-Fadel ◽  
Luis Ángel Hernández-Arenas ◽  
Marco Polo Macías-Morales ◽  
Adriana Rodríguez-Gómez ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Solitary Fibrous Tumor ◽  
Paraneoplastic Syndrome ◽  
Bronchogenic Carcinoma ◽  
Hypertrophic Osteoarthropathy ◽  
Soft Tissue Calcification ◽  
Bone Surface ◽  
Rare Association ◽  
Solitary Fibrous Tumors ◽  
Fibrous Tumor

A solitary fibrous tumor originates in the pleura with variable degrees of invasion. Hypertrophic osteoarthropathy, known as Pierre-Marie-Bamberger syndrome, is characterized by clubbing of the fingers due to bone surface and soft tissue calcification, historically known as a bronchogenic carcinoma paraneoplastic syndrome; however, a few cases have been associated with solitary fibrous tumors. We describe the case of a 38-year-old woman who presented with clubbing of the fingers. Studies revealed an intrathoracic fibrous tumor that was successfully treated with improvement in symptoms.

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