Real-time optical coherence tomography of the anterior segment using hand-held and slit-lamp adapted systems

2002 ◽  
Author(s):  
Sunita Radhakrishnan ◽  
Chetan A. Patil ◽  
Andrew M. Rollins ◽  
Diana Reeves ◽  
Jonathan H. Lass ◽  
...  
Author(s):  
Chetan A. Patil ◽  
Bradley A. Bower ◽  
Volker Westphal ◽  
Sung W. Jeon ◽  
Andrew M. Rollins ◽  
...  

2021 ◽  
pp. bjophthalmol-2021-318847
Author(s):  
Marcus Ang ◽  
Valencia Foo ◽  
Mengyuan Ke ◽  
Bingyao Tan ◽  
Louis Tong ◽  
...  

PurposeTo study the role of two anterior segment optical coherence tomography angiography (AS-OCTA) systems in eyes with acute chemical injury.MethodsProspective study in subjects with unilateral chemical injuries. Sequential slit-lamp assessment with spectral domain (SD) (AngioVue, Optovue, USA) and swept source (SS) (Plex Elite, Zeiss, Carl Zeiss Meditec, Dublin, California, USA) AS-OCTA was performed in both eyes within 24–48 hours of injury. Subjects were managed with a standard clinical protocol and followed-up for 3 months. We assessed limbal disruption (loss of normal limbal vessel architecture), limbal vessel density measurements and agreement (kappa coefficient, κ) between masked assessors of limbal disruption based on AS-OCTA scans and slit-lamp assessment.ResultsTen subjects with median age 31 (25–33) years, 20% women, 60% suffered alkali injuries (Roper-Hall grade 1.5±0.7, Dua grade 2.3±1.2) at presentation. Mean limbal vessel density was lower in quadrants of affected eyes compared with controls detected by SD AS-OCTA (9.4%±2.0% vs 15.5%±1.8%, p<0.001) and SS AS-OCTA (8.8%±2.5% vs 13.9%±1.3%, p=0.01). There was substantial agreement when assessing limbal disruption on AS-OCTA (κ=0.7) compared with slit-lamp evaluation (κ=0.4). Overall, we found good agreement between SD and SS AS-OCTA systems in assessing limbal vessel density in eyes with chemical injury at presentation (mean paired difference: −1.08, 95% CI −3.2 to 0.5; p=0.189).ConclusionsIn this pilot study, AS-OCTA provided objective, non-contact, rapid assessment of limbal vasculature involvement in eyes with acute chemical injury. Further studies are required to establish the role of AS-OCTA in determining the prognosis of eyes with chemical injury.


1970 ◽  
Vol 3 (1) ◽  
pp. 9-12 ◽  
Author(s):  
MN Welch ◽  
CD Reilly ◽  
K Kalwerisky ◽  
A Johnson ◽  
SG Waller

Introduction: Slit-lamp beam measurements of a pterygium can be difficult to reproduce accurately. Purpose: To compare standard slit-lamp beam measurements of pterygia to computer caliper measurements of Anterior Segment Optical Coherence Tomography (OCT) images. Subjects and methods: Thirteen pterygia of ten patients were evaluated. Two physicians independently measured each pterygium using the slit lamp beam. Caliper measurements of two different OCT images of each pterygium were obtained. All measurements determined the distance from the limbus to the pterygium apex. Results: The difference in the slit lamp beam measurements of each pterygium was calculated and the mean of the differences was 0.3 and the standard deviation was 0.32. The difference in the two OCT measurements of each pterygium was also calculated and the mean of the differences was 0.1 and the standard deviation was 0.12. A two-tailed t-test demonstrated a statistically significant difference in these measurements (p = 0.0256). Conclusion: Anterior Segment Optical Coherence Tomography (OCT) gives significantly more reproducible results than the slit lamp beam for measurements of the distance of a pterygium’s apex from the limbus. This tool may provide more accurate clinical assessment of extension of pterygia onto the cornea and may be useful for research purposes. Key words: pterygium; pterygia; anterior segment optical coherence tomography; OCT DOI: 10.3126/nepjoph.v3i1.4271Nepal J Ophthalmol 2011;3(5):9-12


2021 ◽  
Vol 10 (13) ◽  
pp. 2841
Author(s):  
Ahmed A. Abdelghany ◽  
Francesco D’Oria ◽  
Jorge Alio Del Barrio ◽  
Jorge L. Alio

Anterior segment optical coherence tomography (AS-OCT) is a modality that uses low-coherence interferometry to visualize and assess anterior segment ocular features, offering several advantages of being a sterile and noncontact modality that generates high-resolution cross-sectional images of the tissues. The qualitative and quantitative information provided by AS-OCT may be extremely useful for the clinician in the assessment of a wide spectrum of corneal infections, guiding in the management and follow-up of these patients. In clinical practice, infections are routinely evaluated with slit-lamp biomicroscopy, an examination and imaging modality that is limited by the physical characteristics of light. As a consequence, the depth of pathology and the eventually associated corneal edema cannot be accurately measured with the slit-lamp. Therefore, it represents a limit for the clinician, as in vivo information about corneal diseases and the response to treatment is limited. Resolution of corneal infection is characterized by an early reduction in corneal edema, followed by a later reduction in infiltration: both parameters can be routinely measured with standardized serial images by AS-OCT.


2014 ◽  
Vol 04 (02) ◽  
pp. 40-45
Author(s):  
Liamet Fernández Argones ◽  
Ibrain Piloto Díaz ◽  
Sirley Sibello Deustua ◽  
Carmen María Padilla González

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