Addressing nonlinear propagation effects in characterization of high intensity focused ultrasound fields and prediction of thermal and mechanical bioeffects in tissue

2013 ◽  
Vol 134 (5) ◽  
pp. 4153-4153
Author(s):  
Vera A. Khokhlova ◽  
Petr V. Yuldashev ◽  
Wayne Kreider ◽  
Oleg A. Sapozhnikov ◽  
Michael R. Bailey ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Nonlinear Propagation ◽  
Propagation Effects

Nonlinear Derating of High-Intensity Therapeutic Ultrasound Beams Using Gaussian Modal Sums

2013 ◽  
Author(s):  
Seyed Ahmad Reza Dibaji ◽  
Matthew R. Myers ◽  
Joshua E. Soneson ◽  
Rupak K. Banerjee
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Nonlinear Propagation ◽  
Tissue Temperature ◽  
Medical Procedure ◽  
Pressure Amplitude ◽  
Pressure Trace ◽  
The Difference ◽  
Semi Empirical

High intensity focused ultrasound (HIFU) is a noninvasive medical procedure during which a large amount of energy is deposited in a short duration which causes sudden localized rise in tissue temperature, and ultimately, cell necrosis. In assessing the influence of HIFU on biological tissue, semi-empirical mathematical models can be useful for predicting thermal effects. These models require values of the pressure amplitude in the tissue of interest, which can be difficult to obtain experimentally. One common method for estimating the pressure amplitude in tissue is to operate the HIFU transducer in water, measure the pressure amplitude, then multiply by a scaling factor that accounts for the difference in attenuation between water and tissue. This procedure can be accurate when the ultrasound amplitude is low, and the pressure trace in tissue is proportional to that in water. Because of this proportionality, the procedure for reducing the amplitude from water to tissue is called linear derating. At higher intensities, however, harmonics of the fundamental frequency are generated due to nonlinear propagation effects. Higher harmonics are attenuated differently in water and tissue (Hamilton and Blackstock [1]), and the pressure waves in water and tissue are no longer proportional to one another. Techniques for nonlinearly transforming pressure amplitudes measured in water to values appropriate for tissue are therefore desirable when bioeffects of higher intensity procedures are being studied. These techniques are labeled “nonlinear derating”.

Effects of soft tissue inhomogeneities on nonlinear propagation and shock formation in high intensity focused ultrasound beams

2017 ◽  
Vol 141 (5) ◽  
pp. 3548-3548 ◽  
Author(s):  
Petr V. Yuldashev ◽  
Anastasia S. Bobina ◽  
Tatiana D. Khokhlova ◽  
Adam D. Maxwell ◽  
Wayne Kreider ◽  
...  
Keyword(s):  
Soft Tissue ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Nonlinear Propagation ◽  
Shock Formation

scholarly journals Design and characterization of dual-curvature 1.5-dimensional high-intensity focused ultrasound phased-array transducer

2012 ◽  
Vol 59 (1) ◽  
pp. 150-155 ◽  
Author(s):  
Gin-Shin Chen ◽  
Che-Yu Lin ◽  
Jong Seob Jeong ◽  
J. M. Cannata ◽  
Win-Li Lin ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Phased Array ◽  
High Intensity Focused Ultrasound ◽  
Array Transducer

scholarly journals Acoustic characterization of high intensity focused ultrasound fields: A combined measurement and modeling approach

2008 ◽  
Vol 124 (4) ◽  
pp. 2406-2420 ◽  
Author(s):  
Michael S. Canney ◽  
Michael R. Bailey ◽  
Lawrence A. Crum ◽  
Vera A. Khokhlova ◽  
Oleg A. Sapozhnikov
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Modeling Approach ◽  
Acoustic Characterization

Characterization of nonlinear field of a dual-mode linear array for image-guided applications of pulsed high-intensity focused ultrasound

2021 ◽  
Vol 150 (4) ◽  
pp. A86-A86
Author(s):  
Vera A. Khokhlova ◽  
Petr V. Yuldashev ◽  
Randall P. Williams ◽  
Maria M. Karzova ◽  
Azamat Z. Kaloev ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Linear Array ◽  
High Intensity Focused Ultrasound ◽  
Nonlinear Field ◽  
Dual Mode ◽  
Image Guided

Acoustic field characterization of a clinical magnetic resonance-guided high-intensity focused ultrasound system inside the magnet bore

2017 ◽  
Vol 44 (9) ◽  
pp. 4890-4899 ◽  
Author(s):  
Satya V.V.N. Kothapalli ◽  
Michael B. Altman ◽  
Ari Partanen ◽  
Leighton Wan ◽  
H. Michael Gach ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Acoustic Field ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Ultrasound System
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