A non-convex regularization based line artefact quantification method in lung ultrasound imagery for pulmonary disease evaluation

2020 ◽  
Vol 148 (4) ◽  
pp. 2735-2735
Author(s):  
Oktay Karakus ◽  
Nantheera Anantrasirichai ◽  
Adrian Basarab ◽  
Alin Achim
2021 ◽  
Vol 8 (1) ◽  
pp. e000947
Author(s):  
Robert M Fairchild ◽  
Audra Horomanski ◽  
Diane A Mar ◽  
Gabriela R Triant ◽  
Rong Lu ◽  
...  

BackgroundThe majority of patients with SARS-CoV-2 infection are diagnosed and managed as outpatients; however, little is known about the burden of pulmonary disease in this setting. Lung ultrasound (LUS) is a convenient tool for detection of COVID-19 pneumonia. Identifying SARS-CoV-2 infected outpatients with pulmonary disease may be important for early risk stratification.ObjectivesTo investigate the prevalence, natural history and clinical significance of pulmonary disease in outpatients with SARS-CoV-2.MethodsSARS-CoV-2 PCR positive outpatients (CV(+)) were assessed with LUS to identify the presence of interstitial pneumonia. Studies were considered positive based on the presence of B-lines, pleural irregularity and consolidations. A subset of patients underwent longitudinal examinations. Correlations between LUS findings and patient symptoms, demographics, comorbidities and clinical outcomes over 8 weeks were evaluated.Results102 CV(+) patients underwent LUS with 42 (41%) demonstrating pulmonary involvement. Baseline LUS severity scores correlated with shortness of breath on multivariate analysis. Of the CV(+) patients followed longitudinally, a majority showed improvement or resolution in LUS findings after 1–2 weeks. Only one patient in the CV(+) cohort was briefly hospitalised, and no patient died or required mechanical ventilation.ConclusionWe found a high prevalence of LUS findings in outpatients with SARS-CoV-2 infection. Given the pervasiveness of pulmonary disease across a broad spectrum of LUS severity scores and lack of adverse outcomes, our findings suggest that LUS may not be a useful as a risk stratification tool in SARS-CoV-2 in the general outpatient population.


CHEST Journal ◽  
2021 ◽  
Vol 159 (1) ◽  
pp. 205-211 ◽  
Author(s):  
Scott J. Millington ◽  
Seth Koenig ◽  
Paul Mayo ◽  
Giovanni Volpicelli

Author(s):  
Daniel T. Marggrander ◽  
Sinem Koç-Günel ◽  
Nesrin Tekeli-Camcı ◽  
Simon Martin ◽  
Rejane Golbach ◽  
...  

Author(s):  
Chiara De Molo ◽  
Silvia Consolini ◽  
Veronica Salvatore ◽  
Alice Grignaschi ◽  
Antonella Lanotte ◽  
...  

Abstract Aim Lung ultrasound (LUS) is a reliable, radiation-free, and bedside imaging technique used to assess several pulmonary diseases. Although COVID-19 is diagnosed with a nasopharyngeal swab, detection of pulmonary involvement is crucial for safe patient discharge. Computed tomography (CT) is currently the gold standard. To treat paucisymptomatic patients, we have implemented a “fast track” pathway in our emergency department, using LUS as a valid alternative. Minimal data is available in the literature about interobserver reliability and the level of expertise needed to perform a reliable examination. Our aim was to assess these. Materials and Methods This was a single-center prospective study. We enrolled 96 patients. 12 lung areas were explored in each patient with a semiquantitative assessment of pulmonary aeration loss in order to obtain the LUS score. Scans were performed by two different operators, an expert and a novice, who were blinded to their colleague’s results. Results 96 patients were enrolled. The intraclass correlation coefficient (ICC) showed excellent agreement between the expert and the novice operator (ICC 0.975; 0.962–0.983); demographic features (age, sex, and chronic pulmonary disease) did not influence the reproducibility of the method. The ICC was 0.973 (0.950–0.986) in males, 0.976 (0.959–0.986) in females; 0.965 (0.940–0.980) in younger patients (≤ 46 yrs), and 0.973 (0.952–0.985) in older (> 46 yrs) patients. The ICC was 0.967 (0.882–0.991) in patients with pulmonary disease and 0.975 (0.962–0.984) in the other patients. The learning curve showed an increase in interobserver agreement. Conclusion Our results confirm the feasibility and reproducibility of the method among operators with different levels of expertise, with a rapid learning curve.


Author(s):  
Erika Poggiali ◽  
Andrea Vercelli ◽  
Teresa Iannicelli ◽  
Valentina Tinelli ◽  
Laura Celoni ◽  
...  

We describe the case of a male patient admitted to our emergency department during the Italian COVID-19 epidemic, for progressive worsening dyspnoea. A diagnosis of pneumothorax and diffuse interstitial lung involvement was promptly made by lung ultrasound and confirmed by an HRCT scan. A chest CT scan also showed diffuse emphysema, as observed in chronic obstructive pulmonary disease (COPD), and small consolidations in the lower lobes, suggestive for COVID-19 pneumonia. A chest tube was immediately inserted in the emergency room with complete resolution of the dyspnoea. A nasopharyngeal swab for 2019-nCoV was positive. Unfortunately, the patient died from COVID-19-related acute respiratory distress syndrome after 48 days of hospitalization.


2016 ◽  
Vol 18 (2) ◽  
pp. 177
Author(s):  
Xiao-Zhi Zheng ◽  
Jing Wu ◽  
Xu-Yan Tan

Aims: To explore the feasibility of quantitative evaluation of pulmonary function in patients with chronic obstructive pulmonary disease (COPD) using tissue velocity imaging (TVI) and strain rate imaging (SRI) via transthoracic lung ultrasonography. Material and methods: Eighty inpatients with clinically diagnosed COPD underwent pulmonary function test and transthoracic lung ultrasound on the same day. Lung ultrasound variables and pulmonary function parameters were analyzed. Results: All patients with COPD had faster breathing and significant reduced lung function compared with healthy participants (p<0.05). The lung ultrasound parameters, velocity (max-min, cm/s), displacement (max-min, mm), strain (max-min, %) and strain rate (max-min, 1/s) were significantly higher in patients with COPD (p<0.05). A good negative correlation was found between lung ultrasound variables and pulmonary function parameters in patients with COPD. Stepwise multiple regression analysis indicated that the velocity (max-min, cm/s) was the only independent determinant of FEV1/FVC (%). With the use of FEV1/FVC<70% as the criteria of irreversible pulmonary function impairment to distinguish an abnormal pulmonary function, the area under the ROC was 0.99 for the velocity (max-min, cm/s) of the lung tissue in the process of breathing. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of the cut off value (1.19 cm/s) was 97.63%, 100%, 100%, 80%,  and 98%, respectively (p<0.001). Conclusions: Tissue velocity imaging via transthoracic lung ultrasound is a useful modality in the assessment of pulmonary function in patients with COPD.


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