Effects of Microhydrin® Supplementation on Endurance Performance and Metabolism in Well-Trained Cyclists

2004 ◽  
Vol 14 (5) ◽  
pp. 560-573
Author(s):  
Lee R. Glazier ◽  
Trent Stellingwerff ◽  
Lawrence L. Spriet
Keyword(s):  
Time Trial ◽  
Endurance Performance ◽  
Blood Parameters ◽  
Infrared Spectrometry ◽  
Double Blind ◽  
Spectrometry Analysis ◽  
Time Trial Performance ◽  
Cycling Time Trial ◽  
Oxidation Rates ◽  
Trial Performance

This study investigated whether the supplement Microhydrin® (MH) contains silica hydride bonds (Si-H) and if Microhydrin supplementation increased performance or altered metabolism compared to placebo (PL) during prolonged endurance cycling. Seven endurance-trained male cyclists consumed 9.6 g of MH or PL over 48 h in a randomized, double-blind, crossover design. Subjects cycled at ~ 70% of their VO2peak, coupled with five 2-min bursts at 85% VO2peak to simulate hill climbs over 2 h. Subjects then completed a time trial, which required them to complete 7 kJ/kg body mass as quickly as possible. Infrared spectrometry analysis showed a complete absence of Si-H bonds in MH. There was no difference in time trial performance between the 2 trials (PL: 2257 ± 120 s vs. MH: 2345 ± 152 s). Measured oxygen uptake, respiratory exchange ratio, carbohydrate (MH: 2.99 ± 0.13 g/min; PL: 2.83 ± 0.17 g/min avg. over 2 h) and fat (MH: 0.341 ± 0.06 g/min; PL: 0.361 ± 0.07 g/min) oxidation rates and all blood parameters (lactate, glucose, and free fatty acids) were all unaffected by MH supplementation. The volume of expired CO2 and ventilation were significantly greater with MH supplementation (P ≤ 0.05). The results indicate that oral Microhydrin supplementation does not enhance cycling time trial performance or alter metabolism during prolonged submaximal exercise in endurance-trained cyclists.

Improved Cycling Time-Trial Performance after Ingestion of a Caffeine Energy Drink

2009 ◽  
Vol 19 (1) ◽  
pp. 61-78 ◽  
Author(s):  
John L. Ivy ◽  
Lynne Kammer ◽  
Zhenping Ding ◽  
Bei Wang ◽  
Jeffrey R. Bernard ◽  
...  
Keyword(s):  
Perceived Exertion ◽  
Time Trial ◽  
Endurance Performance ◽  
Energy Drink ◽  
Rating Of Perceived Exertion ◽  
Double Blind ◽  
Time Trial Performance ◽  
Cycling Time Trial ◽  
Cycling Time ◽  
Trial Performance

Context:Not all athletic competitions lend themselves to supplementation during the actual event, underscoring the importance of preexercise supplementation to extend endurance and improve exercise performance. Energy drinks are composed of ingredients that have been found to increase endurance and improve physical performance.Purpose:The purpose of the study was to investigate the effects of a commercially available energy drink, ingested before exercise, on endurance performance.Methods:The study was a double-blind, randomized, crossover design. After a 12-hr fast, 6 male and 6 female trained cyclists (mean age 27.3 ± 1.7 yr, mass 68.9 ± 3.2 kg, and VO2 54.9 ± 2.3 ml · kg–1 · min–1) consumed 500 ml of either flavored placebo or Red Bull Energy Drink (ED; 2.0 g taurine, 1.2 g glucuronolactone, 160 mg caffeine, 54 g carbohydrate, 40 mg niacin, 10 mg pantothenic acid, 10 mg vitamin B6, and 10 μg vitamin B12) 40 min before a simulated cycling time trial. Performance was measured as time to complete a standardized amount of work equal to 1 hr of cycling at 70% Wmax.Results:Performance improved with ED compared with placebo (3,690 ± 64 s vs. 3,874 ± 93 s, p < .01), but there was no difference in rating of perceived exertion between treatments. β-Endorphin levels increased during exercise, with the increase for ED approaching significance over placebo (p = .10). Substrate utilization, as measured by open-circuit spirometry, did not differ between treatments.Conclusion:These results demonstrate that consuming a commercially available ED before exercise can improve endurance performance and that this improvement might be in part the result of increased effort without a concomitant increase in perceived exertion.

Cycling Time Trial Performance 4 Hours After Glycogen-Lowering Exercise Is Similarly Enhanced by Recovery Nondairy Chocolate Beverages Versus Chocolate Milk

2016 ◽  
Vol 26 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Adam U. Upshaw ◽  
Tiffany S. Wong ◽  
Arash Bandegan ◽  
Peter W.R. Lemon
Keyword(s):  
Repeated Measures ◽  
Time Trial ◽  
Chocolate Milk ◽  
Double Blind ◽  
Time Trial Performance ◽  
Cycling Time Trial ◽  
Repeated Measures Design ◽  
Dairy Milk ◽  
Cycling Time ◽  
Trial Performance

Postexercise chocolate milk ingestion has been shown to enhance both glycogen resynthesis and subsequent exercise performance. To assess whether nondairy chocolate beverage ingestion post–glycogen-lowering exercise can enhance 20-km cycling time trial performance 4 hr later, eight healthy trained male cyclists (21.8 ± 2.3y, VO2max = 61.2 ± 1.4 ml·kg-1·min-1; M ± SD) completed a series of intense cycling intervals designed to lower muscle glycogen (Jentjens & Jeukendrup, 2003) followed by 4 hr of recovery and a subsequent 20-km cycling time trial. During the first 2 hr of recovery, participants ingested chocolate dairy milk (DAIRYCHOC), chocolate soy beverage (SOYCHOC), chocolate hemp beverage (HEMPCHOC), low-fat dairy milk (MILK), or a low-energy artificially sweetened, flavored beverage (PLACEBO) at 30-min intervals in a double-blind, counterbalanced repeated-measures design. All drinks, except the PLACEBO (247 kJ) were isoenergetic (2,107 kJ), and all chocolate-flavored drinks provided 1-g CHO·kg body mass-1·h-1. Fluid intake across treatments was equalized (2,262 ± 148 ml) by ingesting appropriate quantities of water based on drink intake. The CHO:PRO ratio was 4:1, 1.5:1, 4:1, and 6:1 for DAIRYCHOC, MILK, SOYCHOC, and HEMPCHOC, respectively. One-way analysis of variance with repeated measures showed time trial performance (DAIRYCHOC = 34.58 ± 2.5 min, SOYCHOC = 34.83 ± 2.2 min, HEMPCHOC = 34.88 ± 1.1 min, MILK = 34.47 ± 1.7 min) was enhanced similarly vs PLACEBO (37.85 ± 2.1) for all treatments (p = .019) These data suggest that postexercise macronutrient and total energy intake are more important for same-day 20-km cycling time trial performance after glycogen-lowering exercise than protein type or protein-to-carbohydrate ratio.

Metabolic Responses When Different Forms of Carbohydrate Energy Are Consumed during Cycling

1993 ◽  
Vol 3 (4) ◽  
pp. 398-407 ◽  
Author(s):  
Manuel Lugo ◽  
William M. Sherman ◽  
Gregory S. Wimer ◽  
Keith Garleb
Keyword(s):  
Time Trial ◽  
Blood Parameters ◽  
Metabolic Responses ◽  
Moderate Intensity ◽  
Liquid Form ◽  
Total Carbohydrate ◽  
Time Trial Performance ◽  
Cycling Time Trial ◽  
And Performance ◽  
Trial Performance

This study examined the effects of consuming the same amount of carbohydrate in solid form, liquid form, or both on metabolic responses during 2 hrs of cycling at 70% peak VO2and on cycling time-trial performance. Subjects consumed 0.4 g carbohydrate/kg body mass before and every 30 min during exercise. The liquid was a 7% carbohydrate-electrolyte beverage and the solid was a sports bar (1171 kJ) in which 76%, 18%, and 6% of total energy was derived from carbohydrate, fat, and protein, respectively. Blood obtained at baseline, before exercise, and every 30 min was analyzed for glucose, insulin, lactate, hemoglobin, hematocrit, and plasma volume. There were no differences among the treatments for the blood parameters. Total carbohydrate oxidation and time-trial performance were also similar among treatments. Under thermoneutral conditions with equal liquid inges-tion, the metabolic and performance responses are similar when consuming carbohydrate as a liquid, solid, or in combination during prolonged, moderate intensity cycling.

scholarly journals Habitual Caffeine Consumption Does Not Affect the Ergogenicity of Coffee Ingestion During a 5 km Cycling Time Trial

2020 ◽  
pp. 1-8
Author(s):  
Neil D. Clarke ◽  
Darren L. Richardson
Keyword(s):  
Time Trial ◽  
Analysis Of Covariance ◽  
Caffeine Intake ◽  
Caffeine Consumption ◽  
Double Blind ◽  
Time Trial Performance ◽  
Cycling Time Trial ◽  
Caffeinated Coffee ◽  
Cycling Time ◽  
Trial Performance

There is growing evidence that caffeine and coffee ingestion prior to exercise provide similar ergogenic benefits. However, there has been a long-standing paradigm that habitual caffeine intake may influence the ergogenicity of caffeine supplementation. The aim of the present study was to investigate the effect of habitual caffeine intake on 5-km cycling time-trial performance following the ingestion of caffeinated coffee. Following institutional ethical approval, in a double-blind, randomized, crossover, placebo-controlled design, 46 recreationally active participants (27 men and 19 women) completed a 5-km cycling time trial on a cycle ergometer 60 m in following the ingestion of 0.09 g/kg coffee providing 3 mg/kg of caffeine, or a placebo. Habitual caffeine consumption was assessed using a caffeine consumption questionnaire with low habitual caffeine consumption defined as <3 and ≥6 mg · kg−1 · day−1 defined as high. An analysis of covariance using habitual caffeine intake as a covariant was performed to establish if habitual caffeine consumption had an impact on the ergogenic effect of coffee ingestion. Sixteen participants were classified as high-caffeine users and 30 as low. Ingesting caffeinated coffee improved 5-km cycling time-trial performance by 8 ± 12 s; 95% confidence interval (CI) [5, 13]; p < .001; d = 0.30, with low, 9±14 s; 95% CI [3, 14]; p = .002; d = 0.18, and high, 8 ± 10 s; 95% CI [−1, 17]; p = .008; d = 0.06, users improving by a similar magnitude, 95% CI [−12, 12]; p = .946; d = 0.08. In conclusion, habitual caffeine consumption did not affect the ergogenicity of coffee ingestion prior to a 5-km cycling time trial.

No Improvement in Endurance Performance after a Single Dose of Beetroot Juice

2012 ◽  
Vol 22 (6) ◽  
pp. 470-478 ◽  
Author(s):  
Naomi M. Cermak ◽  
Peter Res ◽  
Rudi Stinkens ◽  
Jon O. Lundberg ◽  
Martin J. Gibala ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Time Trial ◽  
Endurance Performance ◽  
Beetroot Juice ◽  
Double Blind ◽  
Single Bolus ◽  
Time Trial Performance ◽  
Subsequent Time ◽  
The Impact ◽  
Trial Performance

Introduction:Dietary nitrate supplementation has received much attention in the literature due to its proposed ergogenic properties. Recently, the ingestion of a single bolus of nitrate-rich beetroot juice (500 ml, ~6.2 mmol NO3−) was reported to improve subsequent time-trial performance. However, this large volume of ingested beetroot juice does not represent a realistic dietary strategy for athletes to follow in a practical, performancebased setting. Therefore, we investigated the impact of ingesting a single bolus of concentrated nitrate-rich beetroot juice (140 ml, ~8.7 mmol NO3−) on subsequent 1-hr time-trial performance in well-trained cyclists.Methods:Using a double-blind, repeated-measures crossover design (1-wk washout period), 20 trained male cyclists (26 ± 1 yr, VO2peak 60 ± 1 ml · kg−1 · min−1, Wmax 398 ± 7.7 W) ingested 140 ml of concentrated beetroot juice (8.7 mmol NO3−; BEET) or a placebo (nitrate-depleted beetroot juice; PLAC) with breakfast 2.5 hr before an ~1-hr cycling time trial (1,073 ± 21 kJ). Resting blood samples were collected every 30 min after BEET or PLAC ingestion and immediately after the time trial.Results:Plasma nitrite concentration was higher in BEET than PLAC before the onset of the time trial (532 ± 32 vs. 271 ± 13 nM, respectively; p < .001), but subsequent time-trial performance (65.5 ± 1.1 vs. 65 ± 1.1 s), power output (275 ± 7 vs. 278 ± 7 W), and heart rate (170 ± 2 vs. 170 ± 2 beats/min) did not differ between BEET and PLAC treatments (all p > .05).Conclusion:Ingestion of a single bolus of concentrated (140 ml) beetroot juice (8.7 mmol NO3−) does not improve subsequent 1-hr time-trial performance in well-trained cyclists.

Carbohydrate and Protein Hydrolysate Coingestion’s Improvement of Late-Exercise Time-Trial Performance

2009 ◽  
Vol 19 (2) ◽  
pp. 136-149 ◽  
Author(s):  
Michael J. Saunders ◽  
Rebecca W. Moore ◽  
Arie K. Kies ◽  
Nicholas D. Luden ◽  
Casey A. Pratt
Keyword(s):  
Muscle Soreness ◽  
Protein Hydrolysate ◽  
Casein Hydrolysate ◽  
Time Trial ◽  
Double Blind ◽  
Exercise Time ◽  
Time Trial Performance ◽  
Oxidation Rates ◽  
Double Blind Design ◽  
Trial Performance

This study examined whether a carbohydrate + casein hydrolysate (CHO+ProH) beverage improved time-trial performance vs. a CHO beverage delivering ~60 g CHO/hr. Markers of muscle disruption and recovery were also assessed. Thirteen male cyclists (VO2peak = 60.8 ± 1.6 ml · kg−1 · min−1) completed 2 computer-simulated 60-km time trials consisting of 3 laps of a 20-km course concluding with a 5-km climb (~5% grade). Participants consumed 200 ml of CHO (6%) or CHO+ProH beverage (6% + 1.8% protein hydrolysate) every 5 km and 500 ml of beverage immediately postexercise. Beverage treatments were administered using a randomly counterbalanced, double-blind design. Plasma creatine phosphokinase (CK) and muscle-soreness ratings were assessed immediately before and 24 hr after cycling. Mean 60-km times were 134.4 ± 4.6 and 135.0 ± 4.0 min for CHO+ProH and CHO beverages, respectively. All time differences between treatments occurred during the final lap, with protein hydrolysate ingestion explaining a significant (p < .05) proportion of betweentrials differences over the final 20 km (44.3 ± 1.6, 45.0 ± 1.6 min) and final 5 km (16.5 ± 0.6, 16.9 ± 0.6 min). Plasma CK levels and muscle-soreness ratings increased significantly after the CHO trial (161 ± 53, 399 ± 175 U/L; 15.8 ± 5.1, 37.6 ± 5.7 mm) but not the CHO+ProH trial (115 ± 21, 262 ± 88 U/L; 20.9 ± 5.3, 32.2 ± 7.1 mm). Late-exercise time-trial performance was enhanced with CHO+ProH beverage ingestion compared with a beverage containing CHO provided at maximal exogenous oxidation rates during exercise. CHO+ProH ingestion also prevented increases in plasma CK and muscle soreness after exercise.

Effect of inhaled terbutaline on substrate utilization and 300-kcal time trial performance

2014 ◽  
Vol 117 (10) ◽  
pp. 1180-1187 ◽  
Author(s):  
Anders Kalsen ◽  
Morten Hostrup ◽  
Sebastian Karlsson ◽  
Peter Hemmersbach ◽  
Jens Bangsbo ◽  
...  
Keyword(s):  
Drug Exposure ◽  
Time Trial ◽  
Endurance Performance ◽  
Substrate Utilization ◽  
Submaximal Exercise ◽  
Double Blind ◽  
Muscle Lactate ◽  
Lactate Accumulation ◽  
Time Trial Performance ◽  
Trial Performance

In a randomized, double-blind crossover design, we investigated the effect of the beta2-agonist terbutaline (TER) on endurance performance and substrate utilization in nine moderately trained men [maximum oxygen uptake (V̇o2 max) 58.9 ± 3.1 ml·min−1·kg−1]. Subjects performed 60 min of submaximal exercise (65–70% of V̇o2 max) immediately followed by a 300-kcal time trial with inhalation of either 15 mg of TER or placebo (PLA). Pulmonary gas exchange was measured during the submaximal exercise, and muscle biopsies were collected before and after the exercise bouts. Time trial performance was not different between TER and PLA (1,072 ± 145 vs. 1,054 ± 125 s). During the submaximal exercise, respiratory exchange ratio, glycogen breakdown (TER 266 ± 32, PLA 195 ± 28 mmol/kg dw), and muscle lactate accumulation (TER 20.3 ± 1.6, PLA 13.2 ± 1.2 mmol/kg dw) were higher ( P < 0.05) with TER than PLA. There was no difference between TER and PLA in net muscle glycogen utilization or lactate accumulation during the time trial. Intramyocellular triacylglycerol content did not change with treatment or exercise. Pyruvate dehydrogenase-E1α phosphorylation at Ser293 and Ser300 was lower ( P < 0.05) before submaximal exercise with TER than PLA, with no difference after the submaximal exercise and the time trial. Before submaximal exercise, acetyl-CoA carboxylase 2 (ACC2) phosphorylation at Ser221 was higher ( P < 0.05) with TER than PLA. There was no difference in phosphorylation of alpha 5′-AMP-activated protein kinase (αAMPK) at Thr172 between treatments. The present study suggests that beta2-agonists do not enhance 300-kcal time trial performance, but they increase carbohydrate metabolism in skeletal muscles during submaximal exercise independent of AMPK and ACC phosphorylation, and that this effect diminishes as drug exposure time, exercise duration, and intensity are increased.

scholarly journals Isocaloric Carbohydrate Versus Carbohydrate-Protein Ingestion and Cycling Time-Trial Performance

2010 ◽  
Vol 20 (1) ◽  
pp. 34-43 ◽  
Author(s):  
Rebecca J. Toone ◽  
James A. Betts
Keyword(s):  
Perceived Exertion ◽  
Time Trial ◽  
Cycle Ergometer ◽  
Double Blind ◽  
Variable Intensity ◽  
Time Trial Performance ◽  
Cycling Time Trial ◽  
Protein Ingestion ◽  
Cycling Time ◽  
Trial Performance

This study was designed to compare the effects of energy-matched carbohydrate (CHO) and carbohydrate-protein (CHO-PRO) supplements on cycling time-trial performance. Twelve competitive male cyclists and triathletes each completed 2 trials in a randomized and counterbalanced order that were separated by 5–10 d and applied in a double-blind manner. Participants performed a 45-min variable-intensity exercise protocol on a cycle ergometer while ingesting either a 9% CHO solution or a mixture of 6.8% CHO plus 2.2% protein in volumes providing 22 kJ/kg body mass. Participants were then asked to cycle 6 km in the shortest time possible. Blood glucose and lactate concentrations were measured every 15 min during exercise, along with measures of substrate oxidation via indirect calorimetry, heart rate, and ratings of perceived exertion. Mean time to complete the 6-km time trial was 433 ± 21 s in CHO trials and 438 ± 22 s in CHO-PRO trials, which represents a 0.94% (CI: 0.01, 1.86) decrement in performance with the inclusion of protein (p = .048). However, no other variable measured in this study was significantly different between trials. Reducing the quantity of CHO included in a supplement and replacing it with protein may not represent an effective nutritional strategy when the supplement is ingested during exercise. This may reflect the central ergogenic influence of exogenous CHO during such activity.

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