scholarly journals Post-Transcriptional Control of Human Ether-a-go-go-Related Gene Potassium Channel Protein by α-Adrenergic Receptor Stimulation

2010 ◽  
Vol 78 (2) ◽  
pp. 186-197 ◽  
Author(s):  
Jian Chen ◽  
Kun Chen ◽  
Jakub Sroubek ◽  
Zhi-Yuan Wu ◽  
Dierk Thomas ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Adrenergic Receptor ◽  
Transcriptional Control ◽  
Related Gene ◽  
Receptor Stimulation ◽  
Channel Protein

Down-regulation of ether-a-go-go-related gene potassium channel protein through sustained stimulation of AT1 receptor by angiotensin II

2014 ◽  
Vol 452 (3) ◽  
pp. 852-857 ◽  
Author(s):  
Yue Cai ◽  
Yuhong Wang ◽  
Jia Xu ◽  
Xu Zuo ◽  
Yanfang Xu
Keyword(s):  
Angiotensin Ii ◽  
Potassium Channel ◽  
At1 Receptor ◽  
Related Gene ◽  
Down Regulation ◽  
Channel Protein ◽  
Stimulation Of

How to Fluorescently Label the Potassium Channel: A Case in hERG

2020 ◽  
Vol 27 (18) ◽  
pp. 3046-3054
Author(s):  
Xiaomeng Zhang ◽  
Beilei Wang ◽  
Zhenzhen Liu ◽  
Yubin Zhou ◽  
Lupei Du
Keyword(s):  
Potassium Channel ◽  
Herg Channel ◽  
Pore Channel ◽  
Design Rationale ◽  
Related Gene ◽  
Open Conformation ◽  
Cardiac Action ◽  
Qt Syndrome ◽  
Herg Channels ◽  
Action Potential Repolarization

hERG (Human ether-a-go-go-related gene) potassium channel, which plays an essential role in cardiac action potential repolarization, is responsible for inherited and druginduced long QT syndrome. Recently, the Cryo-EM structure capturing the open conformation of hERG channel was determined, thus pushing the study on hERG channel at 3.8 Å resolution. This report focuses primarily on summarizing the design rationale and application of several fluorescent probes that target hERG channels, which enables dynamic and real-time monitoring of potassium pore channel affinity to further advance the understanding of the channels.

Translocation of G-Protein β3 subunit from the cytosol pool to the membrane pool by β1-Adrenergic receptor stimulation in perfused rat hearts

1999 ◽  
Vol 58 (9) ◽  
pp. 1497-1500 ◽  
Author(s):  
Ken Kageyama ◽  
Takeshi Murakami ◽  
Kenji Iizuka ◽  
Kumi Sato ◽  
Kazuo Ichihara ◽  
...  
Keyword(s):  
G Protein ◽  
Adrenergic Receptor ◽  
Receptor Stimulation ◽  
Rat Hearts ◽  
Perfused Rat Hearts

scholarly journals Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy

2016 ◽  
pp. ehw086 ◽  
Author(s):  
Britta Stapel ◽  
Michael Kohlhaas ◽  
Melanie Ricke-Hoch ◽  
Arash Haghikia ◽  
Sergej Erschow ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Peripartum Cardiomyopathy ◽  
Toxic Effects ◽  
Receptor Stimulation

scholarly journals Post-transcriptional Control of Human maxiK Potassium Channel Activity and Acute Oxygen Sensitivity by Chronic Hypoxia

2003 ◽  
Vol 278 (51) ◽  
pp. 51422-51432 ◽  
Author(s):  
Matthew E. Hartness ◽  
Stephen P. Brazier ◽  
Chris Peers ◽  
Alan N. Bateson ◽  
Michael L. J. Ashford ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Transcriptional Control ◽  
Chronic Hypoxia ◽  
Oxygen Sensitivity ◽  
Channel Activity ◽  
Potassium Channel Activity

The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (I Kr ) and human ether-a-go-go-related gene (hERG) expression

2017 ◽  
Vol 107 ◽  
pp. 293-301 ◽  
Author(s):  
Yi Fan Teah ◽  
Muhammad Asyraf Abduraman ◽  
Azimah Amanah ◽  
Mohd Ilham Adenan ◽  
Shaida Fariza Sulaiman ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Delayed Rectifier ◽  
Related Gene ◽  
Channel Current ◽  
Delayed Rectifier Potassium Channel ◽  
Cardiac Delayed Rectifier ◽  
Rectifier Potassium Channel
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