scholarly journals Role of G Protein–Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization

2015 ◽  
Vol 88 (2) ◽  
pp. 347-356 ◽  
Author(s):  
Janet D. Lowe ◽  
Helen S. Sanderson ◽  
Alexandra E. Cooke ◽  
Mehrnoosh Ostovar ◽  
Elena Tsisanova ◽  
...  
2001 ◽  
Vol 60 (5) ◽  
pp. 1049-1056 ◽  
Author(s):  
Carina Shayo ◽  
Natalia Fernandez ◽  
Bibiana Lemos Legnazzi ◽  
Federico Monczor ◽  
Alejandro Mladovan ◽  
...  

2018 ◽  
Vol 14 (2) ◽  
pp. 189-203 ◽  
Author(s):  
Shan Yu ◽  
Litao Sun ◽  
Yufei Jiao ◽  
Leo Tsz On Lee

Physiology ◽  
1997 ◽  
Vol 12 (4) ◽  
pp. 145-152 ◽  
Author(s):  
SSG Ferguson ◽  
J Zhang ◽  
LS Barak ◽  
MG Caron

G protein-coupled receptor kinases and arrestin proteins are well-characterized mediators of agonist-dependent G protein-coupled receptor desensitization. These proteins are now shown to play a dual role in receptor regulation by mediating both receptor uncoupling and sequestration, a process important for receptor resensitization. b-Arrestins bound to phosporylated b2-adrenergic and angiotensin II type 1A receptors act as intracellular trafficking molecules specifically targeting these receptors for dynamin-dependent clathrin-coated vesicle-mediated sequestration.


2014 ◽  
Vol 27 ◽  
pp. 10-17 ◽  
Author(s):  
Petronila Penela ◽  
Laura Nogués ◽  
Federico Mayor

2012 ◽  
Vol 6 ◽  
pp. 970-977 ◽  
Author(s):  
Tijana Bojic ◽  
Emina Sudar ◽  
Dimitri Mikhailidis ◽  
Dragan Alavantic ◽  
Esma Isenovic

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