An Electron Microscope Study of Isolated Nuclei of Liver Cells from Laboratory Animals

Science ◽  
1950 ◽  
Vol 111 (2894) ◽  
pp. 670-673 ◽  
Author(s):  
J. J. Angulo ◽  
J. H. L. Watson
1959 ◽  
Vol 6 (3) ◽  
pp. 427-430 ◽  
Author(s):  
Elizabeth H. Leduc ◽  
J. Walter Wilson

An electron microscope study of intranuclear inclusions which occur in giant cells in a transplantable mouse hepatoma and in enlarged liver cells in mice fed a diet containing bentonite demonstrates that these inclusions are formed by invaginations of the nuclear envelope, and corroborates a previous histochemical study which revealed that the contents of the inclusions are of cytoplasmic origin. In the hepatoma cells the intranuclear inclusions are abundant, small, and situated close to the border of the nucleus, and there are wide openings from the cytoplasm into the invaginations whose contents include lipid droplets, ergastoplasm, and structurally normal mitochondria. In the enlarged liver cells the inclusions are fewer in number, generally much larger than those in the hepatoma, hence they extend deeper into the nucleus, and the interior is continuous with the cytoplasm through only a small opening. Some normal ergastoplasm is present within the inclusions but all other constituents are abnormal. Both normal and degenerating mitochondria occur in the cytoplasm but only degenerating ones are found within the inclusions. Both types of inclusions arise in greatly enlarged cells in which an attempt is made to maintain the normal nuclear surface/nuclear volume ratio by the development of the invaginations of the nuclear envelope.


Author(s):  
O. E. Bradfute ◽  
R. E. Whitmoyer ◽  
L. R. Nault

A pathogen transmitted by the eriophyid mite, Aceria tulipae, infects a number of Gramineae producing symptoms similar to wheat spot mosaic virus (1). An electron microscope study of leaf ultrastructure from systemically infected Zea mays, Hordeum vulgare, and Triticum aestivum showed the presence of ovoid, double membrane bodies (0.1 - 0.2 microns) in the cytoplasm of parenchyma, phloem and epidermis cells (Fig. 1 ).


Author(s):  
A. Campos ◽  
J. Vilches ◽  
J. Gomez

Microgranules have been described with different names in keratinized and in nonkeratinized epithelium. In keratinized epithelium it seems clear that the microgranules are lamellated bodies bounded by a membrane which empty their contents into the intercellular space. Their existence in nonkeratinized epithelium is more debatable. Until now the so-called microgranules have been described in nonkeratinized bucal, lingual and cervical epithelium. In the present work we describe the morphology and nature of such structures in human vaginal epithelium.Biopsies from the midlevel of the vaginal mucosa were taken from voluntary fertile women. The specimens were divided into three groups with four vaginal specimens. The first group was obtained in the folicular phase; those of the second in the postovulatory phase and, finally, the last group corresponded to the secretory phase.


1979 ◽  
Vol 41 (04) ◽  
pp. 655-661 ◽  
Author(s):  
L Tranqui ◽  
M H Prandini ◽  
M Suscillon

1980 ◽  
Vol 42 (2) ◽  
pp. 255-268 ◽  
Author(s):  
Shuhei IMAYAMA ◽  
Hiromu KOHDA ◽  
Harukuni URABE

1987 ◽  
Vol 41 (6) ◽  
pp. 1238-1243
Author(s):  
Yohichiroh Soh ◽  
Junroh Tahara ◽  
Takashi Hayashikawa ◽  
Masatoshi Hitaka ◽  
Kohzoh Kubota ◽  
...  

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