Myo-Inositol as an Essential Growth Factor for Normal and Malignant Human Cells in Tissue Culture

Science ◽  
1956 ◽  
Vol 123 (3202) ◽  
pp. 845-847
Author(s):  
Harry Eagle ◽  
Vance I. Oyama ◽  
Mina Levy ◽  
Aaron Freeman
Keyword(s):  
Tissue Culture ◽  
Growth Factor ◽  
Human Cells ◽  
Essential Growth ◽  
Essential Growth Factor

scholarly journals myo-INOSITOL AS AN ESSENTIAL GROWTH FACTOR FOR NORMAL AND MALIGNANT HUMAN CELLS IN TISSUE CULTURE

1957 ◽  
Vol 226 (1) ◽  
pp. 191-205 ◽  
Author(s):  
Harry Eagle ◽  
Vance I. Oyama ◽  
Mina Levy ◽  
Aaron E. Freeman
Keyword(s):  
Tissue Culture ◽  
Growth Factor ◽  
Human Cells ◽  
Essential Growth ◽  
Essential Growth Factor

Myo-Inositol as an Essential Growth Factor for Normal and Malignant Human Cells in Tissue Culture

Science ◽  
1956 ◽  
Vol 123 (3202) ◽  
pp. 845-847 ◽  
Author(s):  
H. EAGLE ◽  
V. I. OYAMA ◽  
M. LEVY ◽  
A. FREEMAN
Keyword(s):  
Tissue Culture ◽  
Growth Factor ◽  
Human Cells ◽  
Essential Growth ◽  
Essential Growth Factor

BIOTIN (BIOS IIB, VITAMIN H)--AN ESSENTIAL GROWTH FACTOR FOR CERTAIN STAPHYLOCOCCI

Science ◽  
1940 ◽  
Vol 91 (2372) ◽  
pp. 576-577 ◽  
Author(s):  
J. R. PORTER ◽  
M. J. PELCZAR
Keyword(s):  
Growth Factor ◽  
Essential Growth ◽  
Essential Growth Factor

Some Chemical Properties of an Essential Growth Factor for Pathogenic Bacteria

1937 ◽  
Vol 59 (1) ◽  
pp. 170-174 ◽  
Author(s):  
Felix Saunders ◽  
I. I. Finkle ◽  
Leon Sternfeld ◽  
Stewart A. Koser
Keyword(s):  
Growth Factor ◽  
Pathogenic Bacteria ◽  
Chemical Properties ◽  
Essential Growth ◽  
Essential Growth Factor

scholarly journals 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and TGF-β3 Mediated-Mouse Embryonic Palatal Mesenchymal Cells

Dose-Response ◽  
2018 ◽  
Vol 16 (4) ◽  
pp. 155932581881063 ◽  
Author(s):  
Gao Liyun ◽  
Jie Xu ◽  
Xiao Li ◽  
Tao Wang ◽  
Weidong Wu ◽  
...  
Keyword(s):  
Growth Factor ◽  
Cleft Palate ◽  
Signaling Pathway ◽  
Transforming Growth Factor ◽  
Treated Group ◽  
Mesenchymal Cells ◽  
Smad Signaling Pathway ◽  
Tetrachlorodibenzo P Dioxin ◽  
Essential Growth ◽  
Essential Growth Factor

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a well-known environmental teratogenic agent for cleft palate. But transforming growth factor β3 (TGF-β3) is an essential growth factor for palatogenesis. This study is to clarify effects of TCDD and TGF-β3 in mouse embryonic palatal mesenchymal (MEPM) cells. The result showed that with increase of TCDD (0.5 nM-10 nM), the expression of TGF-β3 increased, but after 10 nM TCDD, the expression of TGF-β3 reduced. The viabilities of MEPM cells decreased in 10 nM TCDD-treated group. But the viabilities increased in 10 ng/mL TGF-β3-treated group, or the viabilities were between that of them in combination of 10 nM TCDD and 10 ng/mL TGF-β3-treated group. This phenomenon was the same as the motilities. In addition, we found that the expression of phosphorylated Smad2/3 and Smad7 was increased by 10 nM TCDD, 10 ng/mL TGF-β3, or combination of 10 nM TCDD and 10 ng/mL TGF-β3 induced, but the expression of Smad4 was decreased. These data revealed that the TGF-β/Smad signaling pathway affected TCDD and TGF-β3 in MEPM cells.

Sign in / Sign up

Export Citation Format

Share Document