Combination Therapy of Murine Mucormycosis or Aspergillosis with Iron Chelation, Polyenes, and Echinocandins
2011 ◽
Vol 55
(4)
◽
pp. 1768-1770
◽
Keyword(s):
ABSTRACTLiposomal amphotericin B (LAmB) combined wither either micafungin or deferasirox was synergistic in previous murine studies with mucormycosis or aspergillosis. We hypothesized that triple therapy using LAmB, micafungin, and deferasirox could further improve outcomes of mucormycosis or aspergillosis. Triple therapy improved survival and reduced tissue fungal burden of mice with mucormycosis and to a lesser extent with aspergillosis. Continued investigation into the use of triple therapy against mucormycosis and aspergillosis is warranted.
2008 ◽
Vol 53
(2)
◽
pp. 772-775
◽
Keyword(s):
2011 ◽
Vol 56
(1)
◽
pp. 218-230
◽
2019 ◽
Vol 221
(4)
◽
pp. 608-617
◽
2003 ◽
Vol 22
(7)
◽
pp. 653-656
◽
2019 ◽
Vol 6
(Supplement_2)
◽
pp. S576-S576
2020 ◽
Vol 103
(1)
◽
pp. 308-314
2008 ◽
Vol 52
(11)
◽
pp. 4178-4180
◽