scholarly journals Degradation of 1,4-Dioxane and Cyclic Ethers by an Isolated Fungus

2005 ◽  
Vol 71 (3) ◽  
pp. 1254-1258 ◽  
Author(s):  
Kunichika Nakamiya ◽  
Syunji Hashimoto ◽  
Hiroyasu Ito ◽  
John S. Edmonds ◽  
Masatoshi Morita
Keyword(s):  
Oxalic Acid ◽  
Ethylene Glycol ◽  
Glycolic Acid ◽  
Tricarboxylic Acid Cycle ◽  
Glyoxylic Acid ◽  
Sole Source ◽  
Cordyceps Sinensis ◽  
Mass Spectrometry Analysis ◽  
Cyclic Ethers ◽  
Rrna Gene

ABSTRACT By using 1,4-dioxane as the sole source of carbon, a 1,4-dioxane-degrading microorganism was isolated from soil. The fungus, termed strain A, was able to utilize 1,4-dioxane and many kinds of cyclic ethers as the sole source of carbon and was identified as Cordyceps sinensis from its 18S rRNA gene sequence. Ethylene glycol was identified as a degradation product of 1,4-dioxane by the use of deuterated 1,4-dioxane-d 8 and gas chromatography-mass spectrometry analysis. A degradation pathway involving ethylene glycol, glycolic acid, and oxalic acid was proposed, followed by incorporation of the glycolic acid and/or oxalic acid via glyoxylic acid into the tricarboxylic acid cycle.

scholarly journals Oxidation of Glyoxylic Acid to Oxalic Acid by Glycolic Acid Oxidase

1961 ◽  
Vol 236 (5) ◽  
pp. 1280-1284
Author(s):  
K.E. Richardson ◽  
N.E. Tolbert
Keyword(s):  
Oxalic Acid ◽  
Glycolic Acid ◽  
Glyoxylic Acid ◽  
Acid Oxidase

scholarly journals Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
B. Achappa ◽  
D. Madi ◽  
T. Kanchan ◽  
N. K. Kishanlal
Keyword(s):  
Oxalic Acid ◽  
Ethylene Glycol ◽  
Ethyl Alcohol ◽  
Glycolic Acid ◽  
Clinical Suspicion ◽  
Toxic Metabolites ◽  
Ethylene Glycol Poisoning ◽  
High Degree

Ethylene glycol poisoning is not uncommon in India. The ill effects are primarily caused by its toxic metabolites: glycolic acid and oxalic acid. A 70-year-old female presented to our hospital with ataxia after ingestion of ethylene glycol. The reported case describes the management of ethylene glycol poisoning using oral ethyl alcohol as an alternative to the recommended intravenous ethyl alcohol and fomepizole that are not available for use in India. The need for high degree of clinical suspicion, targeted investigations, and early instigation of treatment is of prime importance in cases of ethylene glycol poisoning as it can lead to long-term complications or even death.

Selective hydrogenation of oxalic acid to glycolic acid and ethylene glycol with a ruthenium catalyst

2020 ◽  
Vol 131 (1) ◽  
pp. 139-151
Author(s):  
Jackson H. S. Santos ◽  
Jadiete T. S. Gomes ◽  
Mohand Benachour ◽  
Eliane B. M. Medeiros ◽  
Cesar A. M. Abreu ◽  
...  
Keyword(s):  
Oxalic Acid ◽  
Ethylene Glycol ◽  
Selective Hydrogenation ◽  
Glycolic Acid ◽  
Ruthenium Catalyst

scholarly journals XX. On some compounds and derivatives of acid

1863 ◽  
Vol 153 ◽  
pp. 437-452
Keyword(s):  
Inorganic Chemistry ◽  
Acetic Acid ◽  
Oxalic Acid ◽  
Sulphuric Acid ◽  
Glycolic Acid ◽  
Glyoxylic Acid ◽  
Careful Study ◽  
Organic Substances ◽  
Derivatives Of

Organic substances of simple composition, like marsh-gas, ethylene, alcohol, and acetic acid, are deserving of most careful study, not merely on account of their being repre­sentative members of numerous and important classes of bodies, but also because they form connecting links between the compounds of inorganic chemistry and the more complicated forms of organic nature. Glyoxylic acid belongs to this class of bodies, because it bears the same relation to oxalic acid that sulphurous acid does to sulphuric acid, and because it stands to glycolic acid as common aldehyde, C 2 H 4 O, does to alcohol, C 2 H 6 O. These relations suggested the experiments which will be described in the following pages.

scholarly journals Ethylene Glycol Metabolism by Pseudomonas putida

2012 ◽  
Vol 78 (24) ◽  
pp. 8531-8539 ◽  
Author(s):  
Björn Mückschel ◽  
Oliver Simon ◽  
Janosch Klebensberger ◽  
Nadja Graf ◽  
Bettina Rosche ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Pseudomonas Putida ◽  
Isocitrate Lyase ◽  
Glyoxylic Acid ◽  
Proteome Analysis ◽  
Sole Source ◽  
Malate Synthase ◽  
Targeted Mutagenesis ◽  
Initial Oxidation ◽  
Content Type

ABSTRACTIn this study, we investigated the metabolism of ethylene glycol in thePseudomonas putidastrains KT2440 and JM37 by employing growth and bioconversion experiments, directed mutagenesis, and proteome analysis. We found that strain JM37 grew rapidly with ethylene glycol as a sole source of carbon and energy, while strain KT2440 did not grow within 2 days of incubation under the same conditions. However, bioconversion experiments revealed metabolism of ethylene glycol by both strains, with the temporal accumulation of glycolic acid and glyoxylic acid for strain KT2440. This accumulation was further increased by targeted mutagenesis. The key enzymes and specific differences between the two strains were identified by comparative proteomics. InP. putidaJM37, tartronate semialdehyde synthase (Gcl), malate synthase (GlcB), and isocitrate lyase (AceA) were found to be induced in the presence of ethylene glycol or glyoxylic acid. Under the same conditions, strain KT2440 showed induction of AceA only. Despite this difference, the two strains were found to use similar periplasmic dehydrogenases for the initial oxidation step of ethylene glycol, namely, the two redundant pyrroloquinoline quinone (PQQ)-dependent enzymes PedE and PedH. From these results we constructed a new pathway for the metabolism of ethylene glycol inP. putida. Furthermore, we conclude thatPseudomonas putidamight serve as a useful platform from which to establish a whole-cell biocatalyst for the production of glyoxylic acid from ethylene glycol.

scholarly journals I. On some compounds and derivatives of glyoxylic acid

1863 ◽  
Vol 12 ◽  
pp. 429-430
Keyword(s):  
Oxalic Acid ◽  
Benzoic Acid ◽  
Glycolic Acid ◽  
Glyoxylic Acid ◽  
Benzylic Alcohol ◽  
Derivatives Of

Glyoxylic acid contains one atom of oxygen less than oxalic acid, and may be considered as glycolic acid minus two atoms of hydrogen. It therefore bears to these two acids the same relation that oil of bitter almonds does to benzoic acid and benzylic alcohol. On another occasion it has been shown to possess other properties in common with hydride of benzoyl.

scholarly journals Oxidation of salicylic acid in water by the O3 and UV/O3 processes: removal and reaction byproducts

2020 ◽  
Vol 81 (4) ◽  
pp. 753-762
Author(s):  
Chang Jing ◽  
Wang Shaopo ◽  
Zhang Yaxue ◽  
Wang Yibo ◽  
Zhang Wenjuan ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Organic Carbon ◽  
Oxalic Acid ◽  
Dissolved Organic Carbon ◽  
Total Organic Carbon ◽  
Glycolic Acid ◽  
Ph Value ◽  
Glyoxylic Acid ◽  
Carbon Reduction ◽  
Optimum Ph

Abstract In this study, the removal of salicylic acid (SA) in water by ozone (O3) and ultraviolet/ozone (UV/O3) processes was investigated. Results showed that more than 50% of SA (10 mg/L) could be effectively removed after 1 min during these two processes. However, the UV/O3 process was much more effective than the O3 process for SA mineralization, and the total organic carbon reduction after 30 min was 69.5% and 28.1%, respectively. In the two processes, the optimum pH value for SA removal was 4.3, while that for SA mineralization was 10.0. Both bicarbonate and dissolved organic carbon significantly inhibited SA removal during the two processes. Eleven oxidation byproducts were detected in O3 process, but only four byproducts were observed in UV/O3 process. Three hydroxylation aromatic products were identified as the initial byproducts during SA degradation. Glyoxylic acid monohydrate, glycolic acid, and oxalic acid were accumulated in O3 process but not observed in UV/O3 process. Oxalic acid was the only detected small molecular byproduct in UV/O3 process, and it could be further mineralized, thereby indicating that UV/O3 had a greater potential for degrading both SA and its reaction byproducts.

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