Increased Leptin Expression in Mice with Bacterial Peritonitis is Partially Regulated by Tumor Necrosis Factor Alpha
1998 ◽
Vol 66
(4)
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pp. 1800-1802
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Keyword(s):
Tnf Α
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ABSTRACT Plasma leptin and ob gene mRNA levels were increased in mice following bacterial peritonitis, and blocking an endogenous tumor necrosis factor alpha (TNF-α) response blunted the increase. However, plasma leptin concentrations did not correlate with the associated anorexia. We conclude that leptin expression is under partial regulatory control of TNF-α in peritonitis, but the anorexia is not dependent on increased leptin production.
2006 ◽
Vol 26
(24)
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pp. 9244-9255
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2001 ◽
Vol 69
(11)
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pp. 7169-7172
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2001 ◽
Vol 69
(8)
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pp. 4823-4830
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