scholarly journals Complete Genome of Acute Rheumatic Fever-Associated Serotype M5 Streptococcus pyogenes Strain Manfredo

2006 ◽  
Vol 189 (4) ◽  
pp. 1473-1477 ◽  
Author(s):  
Matthew T. G. Holden ◽  
Annabel Scott ◽  
Inna Cherevach ◽  
Tracey Chillingworth ◽  
Carol Churcher ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Streptococcus Pyogenes ◽  
Complete Genome ◽  
Acute Rheumatic Fever ◽  
Close Relationship

ABSTRACT Comparisons of the 1.84-Mb genome of serotype M5 Streptococcus pyogenes strain Manfredo with previously sequenced genomes emphasized the role of prophages in diversification of S. pyogenes and the close relationship between strain Manfredo and MGAS8232, another acute rheumatic fever-associated strain.

Bacterial Aetiology of Pharyngotonsillitis in Paediatric Age Group in a Tertiary Care Hospital in Kerala

2021 ◽  
Vol 8 (39) ◽  
pp. 3441-3447
Author(s):  
Thushara Ushakumari Bhuvanendran ◽  
Beena V.G.
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Rheumatic Fever ◽  
Streptococcus Pyogenes ◽  
Acute Rheumatic Fever ◽  
Bacterial Pathogens ◽  
Antibiotic Sensitivity ◽  
Acute Glomerulonephritis ◽  
Age Group ◽  
Common Organism

BACKGROUND Pharyngotonsillitis is defined as a spectrum of conditions ranging from inflammation primarily confined to the tonsils to pharyngitis implying generalized inflammation of the whole of pharynx. Children are more prone to get several episodes of pharyngotonsillitis per year during their school years. Pharyngitis caused by Streptococcus pyogenes can cause two non-suppurative complications, acute rheumatic fever and acute glomerulonephritis which is responsible for significant morbidity and mortality. The present study was conducted to identify the prevalence of bacterial pathogens causing pharyngotonsillitis and to study their antibiotic sensitivity pattern that would indicate the optimum line of treatment. METHOD A total of 200 children at the age group of 2 - 12 years who had clinical features of pharyngotonsillitis according to the inclusion criteria were recruited for this study over a period of one year. With the help of a disposable wooden spatula, pus from the pharyngo tonsillar region was collected and processed. Predominant isolates obtained were identified and antibiotic sensitivity was done. RESULTS Bacteria was isolated from 70 samples. Pharyngotonsillitis was found most prevalent at the age group of 8 – 10 years. Intake of cold food stuffs and passive smoking at home was found to have statistically significant association as risk factor for pharyngotonsillitis. Staphylococcus aureus was the most common organism isolated followed by Streptococcus pyogenes. The other organisms isolated were group G and C streptococci, Streptococcus pneumoniae, Pseudomonas aeruginosa and Klebsiella pneumonia sub species (spp) aerogenes. CONCLUSIONS Staphylococcus aureus was the most common organism isolated, followed by Streptococcus pyogenes. All the isolates of beta haemolytic streptococci were found to be sensitive to penicillin. There was increased incidence of resistance to macrolides among the gram-positive isolates except Streptococcus pneumoniae and it may be due to the wide spread use of macrolides injudiciously. All the bacterial pharyngotonsillitis cases were cured with the antibiotic given according to the sensitivity except one case. KEYWORDS Pharyngotonsillitis, Acute Rheumatic Fever, Acute Glomerulonephritis, Bacterial Pathogens, Antibiogram

scholarly journals The role of echocardiography in diagnosing carditis in the setting of acute rheumatic fever

2009 ◽  
Vol 19 (4) ◽  
pp. 419-420
Author(s):  
Alessandra Benettoni ◽  
Emanuela Berton ◽  
Angela De Cunto ◽  
Andrea Taddio ◽  
Loredana Lepore
Keyword(s):  
Rheumatic Fever ◽  
Acute Rheumatic Fever

Utility of Detecting sof Gene as Evidence of Streptococcus pyogenes Infection in Acute Rheumatic Fever

2019 ◽  
Vol 56 (4) ◽  
pp. 311-313
Author(s):  
Nikki Agarwal ◽  
Seema Kapoor ◽  
Ankit Mangla ◽  
Ashok Kumar ◽  
Ravi N. Mandal ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Streptococcus Pyogenes ◽  
Acute Rheumatic Fever

scholarly journals Acute Rheumatic Fever: A Disease of the Past?

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Robert L. Myette
Keyword(s):  
Case Report ◽  
Rheumatic Fever ◽  
Streptococcus Pyogenes ◽  
Acute Rheumatic Fever ◽  
Healthy Children ◽  
Marginalized Populations ◽  
Urban Hospital ◽  
Urban Centers ◽  
The Past ◽  
Delays In Diagnosis

Introduction. Acute rheumatic fever (ARF) is a manifestation of the nonsuppurative sequelae of Streptococcus pyogenes infection. Herein, two cases of ARF are presented to highlight that this disease is present in urban cities, can be diagnosed in otherwise healthy children, and that its diagnosis may be challenging, or marred with confounders, leading to delays in diagnosis. Case Report. Two unrelated children, age 7 and 9, presented to an urban hospital in Canada with unique manifestations of ARF. Diagnosis of ARF in the first patient was interrupted by a course of steroids which masked symptoms leading to therapeutic delays. The second patient presented with facial droop and symptoms thought to be viral, thus leading to misdiagnosis as Bell’s palsy. Discussion/Conclusion. ARF is more common in underserviced and marginalized populations, which may lead clinicians in urban centers to overlook signs or symptoms suggestive of ARF because they no longer see this condition routinely, or they believe it is a disease of the past.

The role of viral agents in aetiopathogenesis of acute rheumatic fever

2010 ◽  
Vol 30 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Rana Olgunturk ◽  
Ilyas Okur ◽  
Meltem Y. Cirak ◽  
Ayse Deniz Oguz ◽  
Nursel Akalin ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Acute Rheumatic Fever
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